Fingerprint The fingerprint is based on mining the text of the scientific documents related to the associated persons. Based on that an index of weighted terms is created, which defines the key subjects of research unit

Tumor Necrosis Factor-alpha Medicine & Life Sciences
Toll-Like Receptors Medicine & Life Sciences
Innate Immunity Medicine & Life Sciences
Mutation Medicine & Life Sciences
Ubiquitin Medicine & Life Sciences
Proteins Medicine & Life Sciences
Genes Medicine & Life Sciences
Ubiquitination Medicine & Life Sciences

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 1974 2019

Autophagy induction via STING trafficking is a primordial function of the cGAS pathway

Gui, X., Yang, H., Li, T., Tan, X., Shi, P., Li, M., Du, F. & Chen, Z., Mar 14 2019, In : Nature. 567, 7747, p. 262-266 5 p.

Research output: Contribution to journalLetter

Autophagy
Interferons
GMP synthase (glutamine-hydrolyzing)
Phosphotransferases
Sea Anemones

cGAS in action: Expanding roles in immunity and inflammation

Ablasser, A. & Chen, Z., Mar 8 2019, In : Science (New York, N.Y.). 363, 6431

Research output: Contribution to journalReview article

Immunity
Inflammation
DNA
Infection
Therapeutics

Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP

Shang, G., Zhang, C., Chen, Z., Bai, X. & Zhang, X., Mar 21 2019, In : Nature. 567, 7748, p. 389-393 5 p.

Research output: Contribution to journalLetter

Ligands
Chickens
Cryoelectron Microscopy
Interferon Type I
Endoplasmic Reticulum