Digestive & Liver Diseases

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2019

Effect of NGM282, an FGF19 analogue, in primary sclerosing cholangitis: A multicenter, randomized, double-blind, placebo-controlled phase II trial

Hirschfield, G. M., Chazouillères, O., Drenth, J. P., Thorburn, D., Harrison, S. A., Landis, C. S., Mayo, M. J., Muir, A. J., Trotter, J. F., Leeming, D. J., Karsdal, M. A., Jaros, M. J., Ling, L., Kim, K. H., Rossi, S. J., Somaratne, R. M., DePaoli, A. M. & Beuers, U., Mar 2019, In : Journal of Hepatology. 70, 3, p. 483-493 11 p.

Research output: Contribution to journalArticle

25 Scopus citations

Primary Biliary Cholangitis: 2018 Practice Guidance from the American Association for the Study of Liver Diseases

Lindor, K. D., Bowlus, C. L., Boyer, J., Levy, C. & Mayo, M. J., Jan 2019, In : Hepatology. 69, 1, p. 394-419 26 p.

Research output: Contribution to journalArticle

76 Scopus citations
2018

Major hepatic complications in ursodeoxycholic acid-treated patients with primary biliary cholangitis: Risk factors and time trends in incidence and outcome

Harms, M. H., Lammers, W. J., Thorburn, D., Corpechot, C., Invernizzi, P., Janssen, H. L. A., Battezzati, P. M., Nevens, F., Lindor, K. D., Floreani, A., Ponsioen, C. Y., Mayo, M. J., Dalekos, G. N., Bruns, T., Parés, A., Mason, A. L., Verhelst, X., Kowdley, K. V., Goet, J. C., Hirschfield, G. M. & 2 others, Hansen, B. E. & Van Buuren, H. R., Feb 1 2018, In : American Journal of Gastroenterology. 113, 2, p. 254-264 11 p.

Research output: Contribution to journalArticle

24 Scopus citations

Milder disease stage in patients with primary biliary cholangitis over a 44-year period: A changing natural history

on behalf of the GLOBAL PBC Study Group, May 2018, In : Hepatology. 67, 5, p. 1920-1930 11 p.

Research output: Contribution to journalArticle

13 Scopus citations
2016

Stratification of hepatocellular carcinoma risk in primary biliary cirrhosis: A multicentre international study

Trivedi, P. J., Lammers, W. J., Van Buuren, H. R., Parés, A., Floreani, A., Janssen, H. L. A., Invernizzi, P., Battezzati, P. M., Ponsioen, C. Y., Corpechot, C., Poupon, R., Mayo, M. J., Burroughs, A. K., Nevens, F., Mason, A. L., Kowdley, K. V., Lleo, A., Caballeria, L., Lindor, K. D., Hansen, B. E. & 1 others, Hirschfield, G. M., Feb 1 2016, In : Gut. 65, 2, p. 321-329 9 p.

Research output: Contribution to journalArticle

75 Scopus citations

Terlipressin Plus Albumin Is More Effective Than Albumin Alone in Improving Renal Function in Patients with Cirrhosis and Hepatorenal Syndrome Type 1

Boyer, T. D., Sanyal, A. J., Wong, F., Frederick, R. T., Lake, J. R., O'Leary, J. G., Ganger, D., Jamil, K., Pappas, S. C., Sigal, S. H., Munoz, S. J., Patel, V., Kwo, P. Y., Bajaj, J. S., Hassanein, T. I., Shetty, K., Satoskar, R., Reddy, K. R., Mayo, M., Araya, V. & 46 others, Hashemi, N., Feyssa, E., Rossaro, L., Kravetz, D., Grewal, P., Subramanian, R., Korenblat, K., Genyk, Y. S., Regenstein, F., Buell, J. F., Shores, N. J., Emre, S. H., Duchini, A., Zaman, A., Olivera-Martinez, M. A., Porayko, M. K., Befeler, A. S., Reddy, K. G., Del Pilar Hernandez, M., Zucker, S. D., Vargas, H. E., Curry, M., Said, A., Kowdley, K. V., Box, T., Barnes, D. S., Pépin, M. N., Rudraraju, M., Angulo, P., Monsour, H. P., Wolf, D., Howell, C., Regenstein, F. G., Sanchez, A., Elbeshbeshy, H., Fallon, M. B., Swales, C., Sass, D. A., Sotil, E. U., McGuire, B., Gilroy, R. K., Guerrero, J. A., Wong, M. N., Shaikh, O., Gonzalez, S. & Kayali, Z., Jun 1 2016, In : Gastroenterology. 150, 7, p. 1579-1589.e2

Research output: Contribution to journalArticle

84 Scopus citations

The beneficial effect of beta-blockers in patients with cirrhosis, portal hypertension and ascites

Aday, A. W., Mayo, M. J., Elliott, A. & Rockey, D. C., 2016, In : American Journal of the Medical Sciences. 351, 2, p. 169-176 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Updated Etiology and Significance of Elevated Bilirubin During Pregnancy: Changes Parallel Shift in Demographics and Vaccination Status

Duraiswamy, S., Sheffield, J. S., Mcintire, D., Leveno, K. & Mayo, M. J., Sep 1 2016, (Accepted/In press) In : Digestive Diseases and Sciences. p. 1-9 9 p.

Research output: Contribution to journalArticle

Ustekinumab for patients with primary biliary cholangitis who have an inadequate response to ursodeoxycholic acid: A proof-of-concept study

PURIFI Study Group, Jul 1 2016, In : Hepatology. 64, 1, p. 189-199 11 p.

Research output: Contribution to journalArticle

52 Scopus citations
2015

Development and Validation of a Scoring System to Predict Outcomes of Patients with Primary Biliary Cirrhosis Receiving Ursodeoxycholic Acid Therapy

Lammers, W. J., Hirschfield, G. M., Corpechot, C., Nevens, F., Lindor, K. D., Janssen, H. L. A., Floreani, A., Ponsioen, C. Y., Mayo, M. J., Invernizzi, P., Battezzati, P. M., Parés, A., Burroughs, A. K., Mason, A. L., Kowdley, K. V., Kumagi, T., Harms, M. H., Trivedi, P. J., Poupon, R., Cheung, A. & 4 others, Lleo, A., Caballeria, L., Hansen, B. E. & Van Buuren, H. R., Dec 1 2015, In : Gastroenterology. 149, 7, p. 1804-1812.e4

Research output: Contribution to journalArticle

149 Scopus citations

Development of a successful scholarly activity and research program for subspecialty trainees

Mayo, M. J. & Rockey, D. C., Sep 8 2015, In : American Journal of the Medical Sciences. 350, 3, p. 222-227 6 p.

Research output: Contribution to journalArticle

5 Scopus citations

Does preeclampsia involve the pancreas? A report of original research

Nelson, D. B., Duraiswamy, S., McIntire, D. D., Mayo, M. J. & Leveno, K. J., May 1 2015, In : Journal of Maternal-Fetal and Neonatal Medicine. 28, 7, p. 836-838 3 p.

Research output: Contribution to journalArticle

3 Scopus citations

Efficacy of obeticholic acid in patients with primary biliary cirrhosis and inadequate response to ursodeoxycholic acid

Hirschfield, G. M., Mason, A., Luketic, V., Lindor, K., Gordon, S. C., Mayo, M., Kowdley, K. V., Vincent, C., Bodhenheimer, H. C., Parés, A., Trauner, M., Marschall, H. U., Adorini, L., Sciacca, C., Beecher-Jones, T., Castelloe, E., Böhm, O. & Shapiro, D., Apr 1 2015, In : Gastroenterology. 148, 4, p. 751-761.e8

Research output: Contribution to journalArticle

274 Scopus citations

Predicting outcomes of primary biliary cholangitis using the GLOBE score

Mayo, M. J., Dec 1 2015, In : Gastroenterology and Hepatology. 11, 12, p. 842-844 3 p.

Research output: Contribution to journalArticle

2 Scopus citations
2014

Genome-wide analysis of DNA methylation, copy number variation, and gene expression in monozygotic twins discordant for primary biliary cirrhosis

Selmi, C., Cavaciocchi, F., Lleo, A., Cheroni, C., De Francesco, R., Lombardi, S. A., De Santis, M., Meda, F., Raimondo, M. G., Crotti, C., Folci, M., Zammataro, L., Mayo, M. J., Bach, N., Shimoda, S., Gordon, S. C., Miozzo, M., Invernizzi, P., Podda, M., Scavelli, R. & 3 others, Martin, M. R., LaSalle, J. M. & Gershwin, M. E., 2014, In : Frontiers in immunology. 5, MAR, Article 128.

Research output: Contribution to journalArticle

40 Scopus citations

Levels of alkaline phosphatase and bilirubin are surrogate end points of outcomes of patients with primary biliary cirrhosis: An international follow-up study

Global PBC Study Group, Dec 1 2014, In : Gastroenterology. 147, 6, p. 1338-1349.e5

Research output: Contribution to journalArticle

172 Scopus citations
2011

Azathioprine metabolite measurements are not useful for following treatment of autoimmune hepatitis in Alaska Native and other non-Caucasian people

Ferucci, E. D., Hurlburt, K. J., Mayo, M. J., Livingston, S., Deubner, H., Gove, J., Plotnik, J. & McMahon, B. J., Jan 2011, In : Canadian Journal of Gastroenterology. 25, 1, p. 21-27 7 p.

Research output: Contribution to journalArticle

Open Access
14 Scopus citations

Epigenetic investigation of variably X chromosome inactivated genes in monozygotic female twins discordant for primary biliary cirrhosis

Mitchell, M. M., Lleo, A., Zammataro, L., Mayo, M. J., Invernizzi, P., Bach, N., Shimoda, S., Gordon, S. C., Podda, M., Eric Gershwin, M., Selmi, C. & LaSalle, J. M., Jan 2011, In : Epigenetics. 6, 1, p. 95-102 8 p.

Research output: Contribution to journalArticle

63 Scopus citations

Management of autoimmune hepatitis

Mayo, M. J., May 1 2011, In : Current Opinion in Gastroenterology. 27, 3, p. 224-230 7 p.

Research output: Contribution to journalArticle

12 Scopus citations
2010

Acute Pancreatitis During Pregnancy

Tang, S. J., Rodriguez-Frias, E., Singh, S., Mayo, M. J., Jazrawi, S. F., Sreenarasimhaiah, J., Lara, L. F. & Rockey, D. C., Jan 1 2010, In : Clinical Gastroenterology and Hepatology. 8, 1, p. 85-90 6 p.

Research output: Contribution to journalArticle

49 Scopus citations

American association for the study of liver diseases endpoints conference: Design and endpoints for clinical trials in primary biliary cirrhosis

Silveira, M. G., Brunt, E. M., Heathcote, J., Gores, G. J., Lindor, K. D. & Mayo, M. J., Jul 1 2010, In : Hepatology. 52, 1, p. 349-359 11 p.

Research output: Contribution to journalArticle

57 Scopus citations

The 5-D itch scale: A new measure of pruritus

Elman, S., Hynan, L. S., Gabriel, V. & Mayo, M. J., Mar 2010, In : British Journal of Dermatology. 162, 3, p. 587-593 7 p.

Research output: Contribution to journalArticle

193 Scopus citations
2009

Hereditary haemorrhagic telangiectasia involving the bone marrow and liver

Willis, J., Mayo, M. J., Rogers, T. E. & Chen, W., Apr 1 2009, In : British Journal of Haematology. 145, 2, 1 p.

Research output: Contribution to journalArticle

2 Scopus citations

Repair-related activation of hedgehog signaling promotes cholangiocyte chemokine production

Omenetti, A., Syn, W. K., Jung, Y., Francis, H., Porrello, A., Witek, R. P., Choi, S. S., Yang, L., Mayo, M. J., Gershwin, M. E., Alpini, G. & Diehl, A. M., Nov 26 2009, In : Hepatology. 50, 2, p. 518-527 10 p.

Research output: Contribution to journalArticle

79 Scopus citations

Safety and utility of ERCP during pregnancy

Tang, S. J., Mayo, M. J., Rodriguez-Frias, E., Armstrong, L., Tang, L., Sreenarasimhaiah, J., Lara, L. F. & Rockey, D. C., Mar 1 2009, In : Gastrointestinal endoscopy. 69, 3, p. 453-461 9 p.

Research output: Contribution to journalArticle

81 Scopus citations
2008

Prediction of clinical outcomes in primary biliary cirrhosis by serum enhanced liver fibrosis assay

Mayo, M. J., Parkes, J., Adams-Huet, B., Combes, B., Mills, A. S., Markin, R. S., Rubin, R., Wheeler, D., Contos, M., West, A. B., Saldana, S., Getachew, Y., Butsch, R., Luketic, V., Peters, M., Di Bisceglie, A., Bass, N., Lake, J., Boyer, T., Martinez, E. & 4 others, Boyer, J., Garcia-Tsao, G., Barnes, D. & Rosenberg, W. M., Nov 1 2008, In : Hepatology. 48, 5, p. 1549-1557 9 p.

Research output: Contribution to journalArticle

135 Scopus citations
2007

Quality of life and everyday activities in patients with primary biliary cirrhosis

Selmi, C., Gershwin, M. E., Lindor, K. D., Worman, H. J., Gold, E. B., Watnik, M., Utts, J., Invernizzi, P., Kaplan, M. M., Vierling, J. M., Bowlus, C. L., Silveira, M. G., Bossi, I., Askari, F., Bach, N., Bass, N., Benson, G. D., Blei, A., Branch, A. D., Capozza, T. & 19 others, Clain, D. J., Gish, R., Green, R., Harrison, M. E., Herrine, S., Keeffe, E. B., Khazai, N., Kowdley, K. V., Krawitt, E. L., Lake, J., LaBrecque, D., Luketic, V., Mason, A., Mayo, M. J., McCashland, T., Munoz, S., Pockros, P., Rockey, D. & Smith, A. D., Dec 1 2007, In : Hepatology. 46, 6, p. 1836-1843 8 p.

Research output: Contribution to journalArticle

23 Scopus citations

Sertraline as a first-line treatment for cholestatic pruritus

Mayo, M. J., Handem, I., Saldana, S., Jacobe, H., Getachew, Y. & Rush, A. J., Mar 1 2007, In : Hepatology. 45, 3, p. 666-674 9 p.

Research output: Contribution to journalArticle

189 Scopus citations
2006

The relationship between hepatic immunoglobulin production and CD154 expression in chronic liver diseases

Mayo, M. J., Mosby, J. M., Jeyarajah, R., Combes, B., Khilnani, S., Al-Halimi, M., Handem, I., Grammer, A. C. & Lipsky, P. E., Mar 1 2006, In : Liver International. 26, 2, p. 187-196 10 p.

Research output: Contribution to journalArticle

9 Scopus citations
2005

Methotrexate (MTX) plus ursodeoxycholic acid (UDCA) in the treatment of primary biliary cirrhosis

Combes, B., Emerson, S. S., Flye, N. L., Munoz, S. J., Luketic, V. A., Mayo, M. J., McCashland, T. M., Zetterman, R. K., Peters, M. G., Di Bisceglie, A. M., Benner, K. G., Kowdley, K. V., Carithers, R. L., Rosoff, L., Garcia-Tsao, G., Boyer, J. L., Boyer, T. D., Martinez, E. J., Bass, N. M., Lake, J. R. & 10 others, Barnes, D. S., Bonacini, M., Lindsay, K. L., Mills, A. S., Markin, R. S., Rubin, R., West, A. B., Wheeler, D. E., Contos, M. J. & Hofmann, A. F., Nov 1 2005, In : Hepatology. 42, 5, p. 1184-1193 10 p.

Research output: Contribution to journalArticle

94 Scopus citations

Patients and patience: The pitfalls of primary biliary cirrhosis trials

Mayo, M. J., Dec 1 2005, In : Nature Clinical Practice Gastroenterology and Hepatology. 2, 12, p. 552-553 2 p.

Research output: Contribution to journalArticle

4 Scopus citations
2004

Primary biliary cirrhosis in monozygotic and dizygotic twins: Genetics, epigenetics, and environment

Selmi, C., Mayo, M. J., Bach, N., Ishibashi, H., Invernizzi, P., Gish, R. G., Gordon, S. C., Wright, H. I., Zweiban, B., Podda, M. & Gershwin, M. E., Aug 2004, In : Gastroenterology. 127, 2, p. 485-492 8 p.

Research output: Contribution to journalArticle

347 Scopus citations
2003

Extrahepatic manifestations of hepatitis C infection

Mayo, M. J., Mar 1 2003, In : American Journal of the Medical Sciences. 325, 3, p. 135-148 14 p.

Research output: Contribution to journalArticle

115 Scopus citations
95 Scopus citations
2001

RAG1 and RAG2 expression by B cell subsets from human tonsil and peripheral blood

Girschick, H. J., Grammer, A. C., Nanki, T., Mayo, M. & Lipsky, P. E., Jan 1 2001, In : Journal of Immunology. 166, 1, p. 377-386 10 p.

Research output: Contribution to journalArticle

Open Access
57 Scopus citations

Similar T-cell oligoclonality in antimitochondrial antibody-positive and -negative primary biliary cirrhosis

Mayo, M. J., Lipsky, P. E., Miller, S. N., Stastny, P. & Combes, B., Apr 7 2001, In : Digestive Diseases and Sciences. 46, 2, p. 345-351 7 p.

Research output: Contribution to journalArticle

5 Scopus citations
1999

Association of clonally expanded T cells with the syndrome of primary biliary cirrhosis and limited scleroderma

Mayo, M. J., Jenkins, R. N., Combes, B. & Lipsky, P. E., Jun 7 1999, In : Hepatology. 29, 6, p. 1635-1642 8 p.

Research output: Contribution to journalArticle

35 Scopus citations
1996

T-cell receptor Vβ gene utilization in primary biliary cirrhosis

Mayo, M. J., Combes, B. & Jenkins, R. N., Nov 1996, In : Hepatology. 24, 5, p. 1148-1155 8 p.

Research output: Contribution to journalArticle

10 Scopus citations