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2020

L-Arginine sensing regulates virulence gene expression and disease progression in enteric pathogens

Menezes-Garcia, Z., Kumar, A., Zhu, W., Winter, S. E. & Sperandio, V., Jun 2 2020, In : Proceedings of the National Academy of Sciences of the United States of America. 117, 22, p. 12387-12393 7 p.

Research output: Contribution to journalArticle

Optimizing Breast Pocket Irrigation: The Breast Implant-Associated Anaplastic Large Cell Lymphoma (BIA-ALCL) Era

Culbertson, E. J., Felder-Scott, C., Deva, A. K., Greenberg, D. E. & Adams, W. P., May 16 2020, In : Aesthetic surgery journal. 40, 6, p. 619-625 7 p.

Research output: Contribution to journalArticle

Salmonella finds a way: Metabolic versatility of Salmonella enterica serovar Typhimurium in diverse host environments

Taylor, S. J. & Winter, S. E., Jun 2020, In : PLoS pathogens. 16, 6, e1008540.

Research output: Contribution to journalArticle

Open Access

VaMPR: VAriant Mapping and Prediction of antibiotic resistance via explainable features and machine learning

Kim, J., Greenberg, D. E., Pifer, R., Jiang, S., Xiao, G., Shelburne, S. A., Koh, A., Xie, Y. & Zhan, X., Jan 1 2020, In : PLoS Computational Biology. 16, 1, e1007511.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Whole-genome sequencing of Staphylococcus epidermidis bloodstream isolates from a prospective clinical trial reveals that complicated bacteraemia is caused by a limited number of closely related sequence types

Shelburne, S. A., Dib, R. W., Endres, B. T., Reitzel, R., Li, X., Kalia, A., Sahasrabhojane, P., Chaftari, A. M., Hachem, R., Vargas-Cruz, N. S., Jiang, Y., Garey, K., Fowler, V. G., Holland, T. L., Gu, J., Miller, W., Sakurai, A., Arias, C. A., Aitken, S. L., Greenberg, D. E. & 3 others, Kim, J., Flores, A. R. & Raad, I., May 2020, In : Clinical Microbiology and Infection. 26, 5, p. 646.e1-646.e8

Research output: Contribution to journalArticle

Xenosiderophore Utilization Promotes Bacteroides thetaiotaomicron Resilience during Colitis

Zhu, W., Winter, M. G., Spiga, L., Hughes, E. R., Chanin, R., Mulgaonkar, A., Pennington, J., Maas, M., Behrendt, C. L., Kim, J., Sun, X., Beiting, D. P., Hooper, L. V. & Winter, S. E., Mar 11 2020, In : Cell Host and Microbe. 27, 3, p. 376-388.e8

Research output: Contribution to journalArticle

2019

AcrAB-TolC Inhibition by Peptide-Conjugated Phosphorodiamidate Morpholino Oligomers Restores Antibiotic Activity in Vitro and in Vivo

Sturge, C. R., Felder-Scott, C. F., Pifer, R., Pybus, C., Jain, R., Geller, B. L. & Greenberg, D. E., Aug 9 2019, In : ACS infectious diseases. 5, 8, p. 1446-1455 10 p.

Research output: Contribution to journalArticle

2 Scopus citations

Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer

Zhu, W., Miyata, N., Winter, M. G., Arenales, A., Hughes, E. R., Spiga, L., Kim, J., Sifuentes-Dominguez, L., Starokadomskyy, P., Gopal, P., Byndloss, M. X., Santos, R. L., Burstein, E. & Winter, S. E., Jan 1 2019, In : Journal of Experimental Medicine. 216, 10, p. 2378-2393 16 p.

Research output: Contribution to journalArticle

Open Access
9 Scopus citations

Gypsy moth genome provides insights into flight capability and virus–host interactions

Zhang, J., Cong, Q., Rex, E. A., Hallwachs, W., Janzen, D. H., Grishin, N. V. & Gammon, D. B., Jan 29 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 5, p. 1669-1678 10 p.

Research output: Contribution to journalArticle

4 Scopus citations

Host-derived metabolites modulate transcription of salmonella genes involved in L-Lactate utilization during gut colonization

Gillis, C. C., Winter, M. G., Chanin, R. B., Zhu, W., Spiga, L. & Winter, S. E., Apr 1 2019, In : Infection and immunity. 87, 4, e00773.

Research output: Contribution to journalArticle

3 Scopus citations

IIV-6 inhibits NF-ΚB responses in drosophila

West, C., Rus, F., Chen, Y., Kleino, A., Gangloff, M., Gammon, D. B. & Silverman, N., May 2019, In : Viruses. 11, 5, 409.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations

Infection-induced intestinal dysbiosis is mediated by macrophage activation and nitrate production

Wang, S., El-Fahmawi, A., Christian, D. A., Fang, Q., Radaelli, E., Chen, L., Sullivan, M. C., Misic, A. M., Ellringer, J. A., Zhu, X. Q., Winter, S. E., Hunter, C. A. & Beiting, D. P., May 1 2019, In : mBio. 10, 3, e00935-19.

Research output: Contribution to journalArticle

Open Access
5 Scopus citations

STAT2 dependent type i interferon response promotes dysbiosis and luminal expansion of the enteric pathogen Salmonella Typhimurium

Wilson, R. P., Tursi, S. A., Rapsinski, G. J., Medeiros, N. J., Le, L. S., Kotredes, K. P., Patel, S., Liverani, E., Sun, S., Zhu, W., Kilpatrick, L., Winter, S. E., Gamero, A. M. & Tükel, Ç., Apr 2019, In : PLoS pathogens. 15, 4, e1007745.

Research output: Contribution to journalArticle

Open Access
3 Scopus citations

Transition metals and host-microbe interactions in the inflamed intestine

Zhu, W., Spiga, L. & Winter, S., Jun 1 2019, In : BioMetals. 32, 3, p. 369-384 16 p.

Research output: Contribution to journalArticle

2 Scopus citations
2018

Antimicrobial activity of ibuprofen against cystic fibrosis-associated gram-negative pathogens

Shah, P. N., Marshall-Batty, K. R., Smolen, J. A., Tagaev, J. A., Chen, Q., Rodesney, C. A., Le, H. H., Gordon, V. D., Greenberg, D. E. & Cannon, C. L., Mar 2018, In : Antimicrobial agents and chemotherapy. 62, 3, e01574-17.

Research output: Contribution to journalArticle

9 Scopus citations

Antisense Inhibitors Retain Activity in Pulmonary Models of Burkholderia Infection

Daly, S. M., Sturge, C. R., Marshall-Batty, K. R., Felder-Scott, C. F., Jain, R., Geller, B. L. & Greenberg, D. E., May 11 2018, In : ACS Infectious Diseases. 4, 5, p. 806-814 9 p.

Research output: Contribution to journalArticle

6 Scopus citations

Arbovirus infections as screening tools for the identification of viral immunomodulators and host antiviral factors

Rex, E. A., Seo, D. & Gammon, D. B., Sep 13 2018, In : Journal of Visualized Experiments. 2018, 139, e58244.

Research output: Contribution to journalArticle

1 Scopus citations

Bacteria Facilitate Enteric Virus Co-infection of Mammalian Cells and Promote Genetic Recombination

Erickson, A. K., Jesudhasan, P. R., Mayer, M. J., Narbad, A., Winter, S. E. & Pfeiffer, J. K., Jan 10 2018, In : Cell Host and Microbe. 23, 1, p. 77-88.e5

Research output: Contribution to journalArticle

47 Scopus citations

Fabrication and Microscopic and Spectroscopic Characterization of Cytocompatible Self-Assembling Antimicrobial Nanofibers

Xu, D., Chen, W., Tobin-Miyaji, Y. J., Sturge, C. R., Yang, S., Elmore, B., Singh, A., Pybus, C., Greenberg, D. E., Sellati, T. J., Qiang, W. & Dong, H., Jun 27 2018, In : ACS Infectious Diseases. 4, 9, p. 1327-1335 9 p.

Research output: Contribution to journalArticle

9 Scopus citations

Microbial Sensing by Intestinal Myeloid Cells Controls Carcinogenesis and Epithelial Differentiation

Miyata, N., Morris, L. L., Chen, Q., Thorne, C., Singla, A., Zhu, W., Winter, M., Melton, S. D., Li, H., Sifuentes-Dominguez, L., Llano, E., Huff-Hardy, K., Starokadomskyy, P., Lopez, A., Reese, T. A., Turer, E., Billadeau, D. D., Winter, S. E. & Burstein, E., Aug 28 2018, In : Cell Reports. 24, 9, p. 2342-2355 14 p.

Research output: Contribution to journalArticle

2 Scopus citations

Morpholino oligomers tested in vitro, in biofilm and in vivo against multidrug-resistant Klebsiella pneumoniae

Geller, B. L., Li, L., Martinez, F., Sully, E., Sturge, C. R., Daly, S. M., Pybus, C. & Greenberg, D. E., Jun 1 2018, In : Journal of Antimicrobial Chemotherapy. 73, 6, p. 1611-1619 9 p.

Research output: Contribution to journalArticle

5 Scopus citations

Multidrug-resistant Pseudomonas aeruginosa from sputum of patients with cystic fibrosis demonstrates a high rate of susceptibility to ceftazidime–avibactam

Atkin, S. D., Abid, S., Foster, M., Bose, M., Keller, A., Hollaway, R., Sader, H. S., Greenberg, D. E., Finklea, J. D., Castanheira, M. & Jain, R., Jan 1 2018, In : Infection and Drug Resistance. 11, p. 1499-1510 12 p.

Research output: Contribution to journalArticle

5 Scopus citations

Murine colitis reveals a disease-associated bacteriophage community

Duerkop, B. A., Kleiner, M., Paez-Espino, D., Zhu, W., Bushnell, B., Hassell, B., Winter, S. E., Kyrpides, N. C. & Hooper, L. V., Sep 1 2018, In : Nature microbiology. 3, 9, p. 1023-1031 9 p.

Research output: Contribution to journalArticle

33 Scopus citations

Precision editing of the gut microbiota ameliorates colitis

Zhu, W., Winter, M. G., Byndloss, M. X., Spiga, L., Duerkop, B. A., Hughes, E. R., Büttner, L., De Lima Romão, E., Behrendt, C. L., Lopez, C. A., Sifuentes-Dominguez, L., Huff-Hardy, K., Wilson, R. P., Gillis, C. C., Tükel, Ç., Koh, A. Y., Burstein, E., Hooper, L. V., Bäumler, A. J. & Winter, S. E., Jan 11 2018, In : Nature. 553, 7687, p. 208-211 4 p.

Research output: Contribution to journalArticle

123 Scopus citations

Remote acoustic sensing as a safety mechanism during exposure of metal implants to alternating magnetic fields

Cheng, B., Chatzinoff, Y., Szczepanski, D., Bing, C., Shaikh, S., Wyman, O., Perry, C. E., Richardson, J. A., Burns, D. K., Evers, B. M., Greenberg, D. E. & Chopra, R., May 2018, In : PloS one. 13, 5, e0197380.

Research output: Contribution to journalArticle

5 Scopus citations

Successful treatment of persistent Burkholderia cepacia complex bacteremia with ceftazidime-avibactam

Tamma, P. D., Fan, Y., Bergman, Y., Sick-Samuels, A. C., Hsu, A. J., Timp, W., Simner, P. J., Prokesch, B. C. & Greenberg, D. E., Apr 2018, In : Antimicrobial agents and chemotherapy. 62, 4, e02213-17.

Research output: Contribution to journalArticle

7 Scopus citations

Temperature-sensitive liposomal ciprofloxacin for the treatment of biofilm on infected metal implants using alternating magnetic fields

Munaweera, I., Shaikh, S., Maples, D., Nigatu, A. S., Sethuraman, S. N., Ranjan, A., Greenberg, D. E. & Chopra, R., Feb 17 2018, In : International Journal of Hyperthermia. 34, 2, p. 189-200 12 p.

Research output: Contribution to journalArticle

4 Scopus citations

Using Enteric Pathogens to Probe the Gut Microbiota

Spiga, L. & Winter, S. E., Jan 1 2018, (Accepted/In press) In : Trends in Microbiology.

Research output: Contribution to journalArticle

3 Scopus citations

Utilization of host polyamines in alternatively activated macrophages promotes chronic infection by Brucella abortus

Kerrinnes, T., Winter, M. G., Young, B. M., Diaz-Ochoa, V. E., Winter, S. E. & Tsolis, R. M., Mar 1 2018, In : Infection and immunity. 86, 3, e00458-17.

Research output: Contribution to journalArticle

3 Scopus citations
2017

17β-Estradiol dysregulates innate immune responses to Pseudomonas aeruginosa respiratory infection and is modulated by estrogen receptor antagonism

Abid, S., Xie, S. K., Bose, M., Shaul, P. W., Terada, L. S., Brody, S. L., Thomas, P. J., Katzenellenbogen, J. A., Kim, S. H., Greenberg, D. E. & Jain, R., Jan 1 2017, In : Infection and immunity. 85, 10, e00422-17.

Research output: Contribution to journalArticle

15 Scopus citations

An Oxidative Central Metabolism Enables Salmonella to Utilize Microbiota-Derived Succinate

Spiga, L., Winter, M. G., Furtado de Carvalho, T., Zhu, W., Hughes, E. R., Gillis, C. C., Behrendt, C. L., Kim, J., Chessa, D., Andrews-Polymenis, H. L., Beiting, D. P., Santos, R. L., Hooper, L. V. & Winter, S. E., Sep 13 2017, In : Cell Host and Microbe. 22, 3, p. 291-301.e6

Research output: Contribution to journalArticle

37 Scopus citations

Antibiotic-Induced Depletion of Anti-inflammatory Clostridia Is Associated with the Development of Graft-versus-Host Disease in Pediatric Stem Cell Transplantation Patients

Simms-Waldrip, T. R., Sunkersett, G., Coughlin, L. A., Savani, M. R., Arana, C., Kim, J., Kim, M., Zhan, X., Greenberg, D. E., Xie, Y., Davies, S. M. & Koh, A., May 1 2017, In : Biology of Blood and Marrow Transplantation. 23, 5, p. 820-829 10 p.

Research output: Contribution to journalArticle

39 Scopus citations

Caenorhabditis elegans as an emerging model for virus-host interactions

Gammon, D. B., Dec 1 2017, In : Journal of Virology. 91, 23, e00509-17.

Research output: Contribution to journalArticle

7 Scopus citations

Dysbiosis-Associated Change in Host Metabolism Generates Lactate to Support Salmonella Growth

Gillis, C. C., Hughes, E. R., Spiga, L., Winter, M. G., Zhu, W., Furtado de Carvalho, T., Chanin, R. B., Behrendt, C. L., Hooper, L. V., Santos, R. L. & Winter, S. E., Jan 1 2017, (Accepted/In press) In : Cell Host and Microbe.

Research output: Contribution to journalArticle

34 Scopus citations

Employing high-frequency alternating magnetic fields for the non-invasive treatment of prosthetic joint infections

Chopra, R., Shaikh, S., Chatzinoff, Y., Munaweera, I., Cheng, B., Daly, S. M., Xi, Y., Bing, C., Burns, D. & Greenberg, D. E., Dec 1 2017, In : Scientific reports. 7, 1, 7520.

Research output: Contribution to journalArticle

12 Scopus citations

Identification and whole genome sequencing of the first case of Kosakonia radicincitans causing a human bloodstream infection

Bhatti, M. D., Kalia, A., Sahasrabhojane, P., Kim, J., Greenberg, D. E. & Shelburne, S. A., Jan 24 2017, In : Frontiers in Microbiology. 8, JAN, 62.

Research output: Contribution to journalArticle

7 Scopus citations

Inhibition of pseudomonas aeruginosa by peptide-conjugated phosphorodiamidate morpholino oligomers

Howard, J. J., Sturge, C. R., Moustafa, D. A., Daly, S. M., Marshall-Batty, K. R., Felder, C. F., Zamora, D., Yabe-Gill, M., Labandeira-Rey, M., Bailey, S. M., Wong, M., Goldberg, J. B., Geller, B. L. & Greenberg, D. E., Apr 1 2017, In : Antimicrobial Agents and Chemotherapy. 61, 4, e01938.

Research output: Contribution to journalArticle

21 Scopus citations

MCR-1 inhibition with peptide-conjugated phosphorodiamidate morpholino oligomers restores sensitivity to polymyxin in escherichia coli

Daly, S. M., Sturge, C. R., Felder-Scott, C. F., Geller, B. L. & Greenberg, D. E., Nov 1 2017, In : mBio. 8, 6, e01315-17.

Research output: Contribution to journalArticle

20 Scopus citations

Microbial Respiration and Formate Oxidation as Metabolic Signatures of Inflammation-Associated Dysbiosis

Hughes, E. R., Winter, M. G., Duerkop, B. A., Spiga, L., Furtado de Carvalho, T., Zhu, W., Gillis, C. C., Büttner, L., Smoot, M. P., Behrendt, C. L., Cherry, S., Santos, R. L., Hooper, L. V. & Winter, S. E., Feb 8 2017, In : Cell Host and Microbe. 21, 2, p. 208-219 12 p.

Research output: Contribution to journalArticle

76 Scopus citations

Microbiota-derived short-chain fatty acids modulate expression of Campylobacter jejuni determinants required for commensalism and virulence

Luethy, P. M., Huynh, S., Ribardo, D. A., Winter, S. E., Parker, C. T. & Hendrixson, D. R., May 1 2017, In : mBio. 8, 3, e00407-17.

Research output: Contribution to journalArticle

22 Scopus citations

Paneth cells secrete lysozyme via secretory autophagy during bacterial infection of the intestine

Bel, S., Pendse, M., Wang, Y., Ii, Y., Ruhn, K. A., Hassell, B., Leal, T., Winter, S. E., Xavier, R. J. & Hooper, L. V., Sep 8 2017, In : Science. 357, 6355, p. 1047-1052 6 p.

Research output: Contribution to journalArticle

100 Scopus citations

Peptide-conjugated phosphorodiamidate morpholino oligomer (PPMO) restores carbapenem susceptibility to NDM-1-positive pathogens in vitro and in vivo

Sully, E. K., Geller, B. L., Li, L., Moody, C. M., Bailey, S. M., Moore, A. L., Wong, M., Nordmann, P., Daly, S. M., Sturge, C. R. & Greenberg, D. E., Mar 1 2017, In : The Journal of antimicrobial chemotherapy. 72, 3, p. 782-790 9 p.

Research output: Contribution to journalArticle

18 Scopus citations

Respiration of Microbiota-Derived 1,2-propanediol Drives Salmonella Expansion during Colitis

Faber, F., Thiennimitr, P., Spiga, L., Byndloss, M. X., Litvak, Y., Lawhon, S., Andrews-Polymenis, H. L., Winter, S. E. & Bäumler, A. J., Jan 2017, In : PLoS pathogens. 13, 1, e1006129.

Research output: Contribution to journalArticle

48 Scopus citations

The Antiviral RNA Interference Response Provides Resistance to Lethal Arbovirus Infection and Vertical Transmission in Caenorhabditis elegans

Gammon, D. B., Ishidate, T., Li, L., Gu, W., Silverman, N. & Mello, C. C., Mar 20 2017, In : Current Biology. 27, 6, p. 795-806 12 p.

Research output: Contribution to journalArticle

19 Scopus citations

The Growing Threat of Antimicrobial Resistance

Munita, J. M., Shelburne, S., Greenberg, D. E. & Arias, C. A., Feb 1 2017, In : Texas Medicine. 113, 2, p. 48-52 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Whole-genome sequencing accurately identifies resistance to extended-spectrum β-lactams for major gram-negative bacterial pathogens

Shelburne, S. A., Kim, J., Munita, J. M., Sahasrabhojane, P., Shields, R. K., Press, E. G., Li, X., Arias, C. A., Cantarel, B., Jiang, Y., Kim, M. S., Aitken, S. L. & Greenberg, D. E., 2017, In : Clinical Infectious Diseases. 65, 5, p. 738-745 8 p.

Research output: Contribution to journalArticle

16 Scopus citations
2016

Bacterial adrenergic sensors regulate virulence of enteric pathogens in the gut

Moreira, C. G., Russell, R., Mishra, A. A., Narayanan, S., Ritchie, J. M., Waldor, M. K., Curtis, M. M., Winter, S. E., Weinshenker, D. & Sperandio, V., 2016, In : mBio. 7, 3, e00826-16.

Research output: Contribution to journalArticle

37 Scopus citations

Depletion of Butyrate-Producing Clostridia from the Gut Microbiota Drives an Aerobic Luminal Expansion of Salmonella

Rivera-Chávez, F., Zhang, L. F., Faber, F., Lopez, C. A., Byndloss, M. X., Olsan, E. E., Xu, G., Velazquez, E. M., Lebrilla, C. B., Winter, S. E. & Bäumler, A. J., Apr 13 2016, In : Cell Host and Microbe. 19, 4, p. 443-454 12 p.

Research output: Contribution to journalArticle

208 Scopus citations

Energy taxis toward host-derived nitrate supports a salmonella pathogenicity island 1-independent mechanism of invasion

Rivera-Chávez, F., Lopez, C. A., Zhang, L. F., García-Pastor, L., Chávez-Arroyo, A., Lokken, K. L., Tsolis, R. M., Winter, S. E. & Bäumler, A. J., Jul 1 2016, In : mBio. 7, 4, e00960-16.

Research output: Contribution to journalArticle

21 Scopus citations

Iron acquisition pathways and colonization of the inflamed intestine by Salmonella enterica serovar Typhimurium

Costa, L. F., Mol, J. P. S., Silva, A. P. C., Macêdo, A. A., Silva, T. M. A., Alves, G. E. S., Winter, S., Winter, M. G., Velazquez, E. M., Byndloss, M. X., Bäumler, A. J., Tsolis, R. M., Paixão, T. A. & Santos, R. L., Feb 17 2016, (Accepted/In press) In : International Journal of Medical Microbiology.

Research output: Contribution to journalArticle

8 Scopus citations