• 8872 Citations
  • 34 h-Index
20052020

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Article
2020
Open Access

Closing the gap: Contribution of surgical best practices to outcome differences between high- and low-volume centers for lung cancer resection

von Itzstein, M. S., Lu, R., Kernstine, K. H., Halm, E. A., Wang, S., Xie, Y. & Gerber, D. E., Jun 1 2020, In : Cancer Medicine. 9, 12, p. 4137-4147 11 p.

Research output: Contribution to journalArticle

Open Access

DC-HIL/GpNMB is a negative regulator of tumor response to immune checkpoint inhibitors

Chung, J. S., Ramani, V., Kobayashi, M., Fattah, F., Popat, V., Zhang, S., Cruz, P. D., Gerber, D. E. & Ariizumi, K., Mar 15 2020, In : Clinical Cancer Research. 26, 6, p. 1449-1459 11 p.

Research output: Contribution to journalArticle

Definition and coordination of roles and responsibilities among cancer center clinic and research personnel

Craddock Lee, S. J., Reimer, T., Garcia, S., Williams, E. L., West, M., Stuart, T. & Gerber, D. E., Jan 1 2020, In : Journal of oncology practice. 16, 1, p. E64-E74

Research output: Contribution to journalArticle

Open Access

Investigational Biomarkers for Checkpoint Inhibitor Immune-Related Adverse Event Prediction and Diagnosis

von Itzstein, M. S., Khan, S. & Gerber, D. E., Jun 1 2020, In : Clinical chemistry. 66, 6, p. 779-793 15 p.

Research output: Contribution to journalArticle

Lack of Association Between Radiographic Tumor Burden and Efficacy of Immune Checkpoint Inhibitors in Advanced Lung Cancer

Popat, V., Lu, R., Ahmed, M., Park, J. Y., Xie, Y. & Gerber, D. E., Jun 1 2020, In : Oncologist. 25, 6, p. 515-522 8 p.

Research output: Contribution to journalArticle

Open Access

Late-Onset Immunotherapy Toxicity and Delayed Autoantibody Changes: Checkpoint Inhibitor–Induced Raynaud's-Like Phenomenon

Khan, S., von Itzstein, M. S., Lu, R., Bermas, B. L., Karp, D. R., Khan, S. A., Fattah, F. J., Park, J. Y., Saltarski, J. M., Gloria-McCutchen, Y., Xie, Y., Li, Q. Z., Wakeland, E. K. & Gerber, D. E., May 1 2020, In : Oncologist. 25, 5, p. e753-e757

Research output: Contribution to journalArticle

Open Access

Patient familiarity with, understanding of, and preferences for clinical trial endpoints and terminology

von Itzstein, M. S., Railey, E., Smith, M. L., White, C. B., Sledge, G. W., Howell, J. R., Lawton, W., Marinucci, D. M., Unni, N. & Gerber, D. E., Apr 15 2020, In : Cancer. 126, 8, p. 1605-1613 9 p.

Research output: Contribution to journalArticle

Phase 2 study of the focal adhesion kinase inhibitor defactinib (VS-6063) in previously treated advanced KRAS mutant non-small cell lung cancer

Gerber, D. E., Camidge, D. R., Morgensztern, D., Cetnar, J., Kelly, R. J., Ramalingam, S. S., Spigel, D. R., Jeong, W., Scaglioni, P. P., Zhang, S., Li, M., Weaver, D. T., Vaikus, L., Keegan, M., Horobin, J. C. & Burns, T. F., Jan 2020, In : Lung Cancer. 139, p. 60-67 8 p.

Research output: Contribution to journalArticle

2 Scopus citations

Phase Ia study of anti-NAPI2B antibody–drug conjugate lifastuzumab vedotin DNIB0600A in patients with non–small cell lung cancer and platinum-resistant ovarian cancer

Gerber, D. E., Infante, J. R., Gordon, M. S., Goldberg, S. B., Martín, M., Felip, E., Garcia, M. M., Schiller, J., Spigel, D. R., Cordova, J., Westcott, V., Wang, Y., Shames, D. S., Choi, Y. J., Kahn, R., Dere, R. C., Samineni, D., Xu, J., Lin, K., Wood, K. & 7 others, Royer-Joo, S., Lemahieu, V., Schuth, E., Vaze, A., Maslyar, D., Humke, E. W. & Burris, H. A., Jan 15 2020, In : Clinical Cancer Research. 26, 2, p. 364-372 9 p.

Research output: Contribution to journalArticle

Open Access
2 Scopus citations
Open Access

Rates of appropriate laxative prophylaxis for opioid-induced constipation in veterans with lung cancer: a retrospective cohort study

Brown, T. J., Keshvani, N., Gupta, A., Yang, H., Agrawal, D., Le, T. C., Gerber, D. E. & Alvarez, C. A., Jan 1 2020, (Accepted/In press) In : Supportive Care in Cancer.

Research output: Contribution to journalArticle

Stakeholder engagement to initiate lung cancer screening in an urban safety-net health system

Lee, S. J. C., Hamann, H., Browning, T., Santini, N. O., Abbara, S., Balis, D. S., Chiu, H., Moran, B. A., McGuire, M. & Gerber, D. E., Mar 2020, In : Healthcare. 8, 1, 100370.

Research output: Contribution to journalArticle

Statin Intolerance, Anti-HMGCR Antibodies, and Immune Checkpoint Inhibitor-Associated Myositis: A “Two-Hit” Autoimmune Toxicity or Clinical Predisposition?

von Itzstein, M. S., Khan, S., Popat, V., Lu, R., Khan, S., Fattah, F. J., Park, J. Y., Bermas, B. L., Karp, D. R., Ahmed, M., Saltarski, J. M., Gloria-McCutchen, Y., Xie, Y., Li, Q. Z., Wakeland, E. K. & Gerber, D. E., Jan 1 2020, (Accepted/In press) In : Oncologist.

Research output: Contribution to journalArticle

Open Access

Timing, Sites, and Correlates of Lung Cancer Recurrence

Karacz, C. M., Yan, J., Zhu, H. & Gerber, D. E., Mar 2020, In : Clinical lung cancer. 21, 2, p. 127-135.e3

Research output: Contribution to journalArticle

1 Scopus citations

Tracking the Nonenrolled: Lung Cancer Screening Patterns Among Individuals not Accrued to a Clinical Trial

Gerber, D. E., Hamann, H., Chavez, C., Dorsey, O., Santini, N. O., Browning, T., Ochoa, C. D., Adesina, J., Natchimuthu, V. S., Steen, E., Zhu, H. & Lee, S. J. C., Jan 1 2020, (Accepted/In press) In : Clinical lung cancer.

Research output: Contribution to journalArticle

Unique Patterns of Distant Metastases in HPV-Positive Head and Neck Cancer

Sacks, R., Law, J. Y., Zhu, H., Beg, M. S., Gerber, D. E., Sumer, B. D., Myers, L. L., Truelson, J. M., Nedzi, L., Sher, D., Hughes, R. S. & Khan, S. A., Feb 1 2020, In : Oncology (Switzerland). 98, 3, p. 179-185 7 p.

Research output: Contribution to journalArticle

2019

Development and Validation of a Nomogram Prognostic Model for Patients With Advanced Non-Small-Cell Lung Cancer

Wang, T., Lu, R., Lai, S., Schiller, J., Zhou, F. L., Ci, B., Wang, S., Gao, X., Yao, B., Gerber, D. E., Johnson, D. H., Xiao, G. & Xie, Y., Apr 1 2019, In : Cancer Informatics. 18

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Efficacy of EGFR plus TNF inhibition in a preclinical model of temozolomide-resistant glioblastoma

Guo, G., Gong, K., Puliyappadamba, V. T., Panchani, N., Pan, E., Mukherjee, B., Damanwalla, Z., Bharia, S., Hatanpaa, K. J., Gerber, D. E., Mickey, B. E., Patel, T. R., Sarkaria, J. N., Zhao, D., Burma, S. & Habib, A. A., Dec 1 2019, In : Neuro-oncology. 21, 12, p. 1529-1539 11 p.

Research output: Contribution to journalArticle

Open Access
1 Scopus citations

Increasing Numbers and Reported Adverse Events in Patients with Lung Cancer Undergoing Inpatient Lung Biopsies: A Population-Based Analysis

von Itzstein, M. S., Gupta, A., Mara, K. C., Khanna, S. & Gerber, D. E., Oct 1 2019, In : Lung. 197, 5, p. 593-599 7 p.

Research output: Contribution to journalArticle

1 Scopus citations

Mobile device applications for electronic patient portals in oncology

Pho, K. K., Lu, R., Gates, S., Cai, J., Xie, D., Xie, Y., Craddock Lee, S. J. & Gerber, D. E., Jan 1 2019, In : JCO Clinical Cancer Informatics. 3

Research output: Contribution to journalArticle

1 Scopus citations

NQO1-dependent, tumor-selective radiosensitization of non-small cell lung cancers

Motea, E. A., Huang, X., Singh, N., Kilgore, J. A., Williams, N. S., Xie, X. J., Gerber, D. E., Beg, M. S., Bey, E. A. & Boothman, D. A., Apr 15 2019, In : Clinical Cancer Research. 25, 8, p. 2601-2609 9 p.

Research output: Contribution to journalArticle

3 Scopus citations
1 Scopus citations

Type and case volume of health care facility influences survival and surgery selection in cases with early-stage non–small cell lung cancer

Wang, S., Lai, S., von Itzstein, M. S., Yang, L., Yang, D. M., Zhan, X., Xiao, G., Halm, E. A., Gerber, D. E. & Xie, Y., Dec 1 2019, In : Cancer. 125, 23, p. 4252-4259 8 p.

Research output: Contribution to journalArticle

1 Scopus citations

Unique mutation patterns in anaplastic thyroid cancer identified by comprehensive genomic profiling

Khan, S. A., Ci, B., Xie, Y., Gerber, D. E., Beg, M. S., Sherman, S. I., Cabanillas, M. E., Busaidy, N. L., Burtness, B. A., Heilmann, A. M., Bailey, M., Ross, J. S., Sher, D. J. & Ali, S. M., Jun 2019, In : Head and Neck. 41, 6, p. 1928-1934 7 p.

Research output: Contribution to journalArticle

3 Scopus citations

Variation in the Assessment of Immune-Related Adverse Event Occurrence, Grade, and Timing in Patients Receiving Immune Checkpoint Inhibitors

Hsiehchen, D., Watters, M. K., Lu, R., Xie, Y. & Gerber, D. E., Sep 4 2019, In : JAMA network open. 2, 9, p. e1911519

Research output: Contribution to journalArticle

Open Access
4 Scopus citations
2018

Consolidative radiotherapy for limited metastatic non-small-cell lung cancer: A phase 2 randomized clinical trial

Iyengar, P., Wardak, Z., Gerber, D. E., Tumati, V., Ahn, C., Hughes, R. S., Dowell, J. E., Cheedella, N., Nedzi, L., Westover, K. D., Pulipparacharuvil, S., Choy, H. & Timmerman, R. D., Jan 1 2018, In : JAMA oncology. 4, 1, e173501.

Research output: Contribution to journalArticle

180 Scopus citations

Development and Validation of a Nomogram Prognostic Model for SCLC Patients

Wang, S., Yang, L., Ci, B., Maclean, M., Gerber, D. E., Xiao, G. & Xie, Y., Sep 1 2018, In : Journal of Thoracic Oncology. 13, 9, p. 1338-1348 11 p.

Research output: Contribution to journalArticle

7 Scopus citations

Estimating lead-time bias in lung cancer diagnosis of patients with previous cancers

Ge, Z., Heitjan, D. F., Gerber, D. E., Xuan, L. & Pruitt, S. L., Jan 1 2018, (Accepted/In press) In : Statistics in Medicine.

Research output: Contribution to journalArticle

2 Scopus citations

How does autoimmune disease impact treatment and outcomes among patients with lung cancer? A national SEER-Medicare analysis

Khan, S. A., Pruitt, S. L., Xuan, L., Makris, U. & Gerber, D. E., Jan 1 2018, In : Lung Cancer. 115, p. 97-102 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Immune dysregulation in cancer patients developing immune-related adverse events

Khan, S., Khan, S., Luo, X., Fattah, F. J., Saltarski, J., Gloria-McCutchen, Y., Lu, R., Xie, Y., Li, Q., Wakeland, E. K. & Gerber, D. E., Jan 1 2018, (Accepted/In press) In : British Journal of Cancer.

Research output: Contribution to journalArticle

14 Scopus citations

Main bronchus location is a predictor for metastasis and prognosis in lung adenocarcinoma: A large cohort analysis

Yang, L., Wang, S., Gerber, D. E., Zhou, Y., Xu, F., Liu, J., Liang, H., Xiao, G., Zhou, Q., Gazdar, A. & Xie, Y., Jun 1 2018, In : Lung Cancer. 120, p. 22-26 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Nivolumab Plus Erlotinib in Patients With EGFR-Mutant Advanced NSCLC

Gettinger, S., Hellmann, M. D., Chow, L. Q. M., Borghaei, H., Antonia, S., Brahmer, J. R., Goldman, J. W., Gerber, D. E., Juergens, R. A., Shepherd, F. A., Laurie, S. A., Young, T. C., Li, X., Geese, W. J. & Rizvi, N., Jan 1 2018, (Accepted/In press) In : Journal of Thoracic Oncology.

Research output: Contribution to journalArticle

27 Scopus citations

Phase 1 study of ARQ 761, a β-lapachone analogue that promotes NQO1-mediated programmed cancer cell necrosis

Gerber, D. E., Beg, M. S., Fattah, F., Frankel, A. E., Fatunde, O., Arriaga, Y., Dowell, J. E., Bisen, A., Leff, R. D., Meek, C. C., Putnam, W. C., Kallem, R. R., Subramaniyan, I., Dong, Y., Bolluyt, J., Sarode, V., Luo, X., Xie, Y., Schwartz, B. & Boothman, D. A., Oct 16 2018, In : British journal of cancer. 119, 8, p. 928-936 9 p.

Research output: Contribution to journalArticle

7 Scopus citations
26 Scopus citations

Randomized phase 2 study of tivantinib plus erlotinib versus single-agent chemotherapy in previously treated KRAS mutant advanced non-small cell lung cancer

Gerber, D. E., Socinski, M. A., Neal, J. W., Wakelee, H. A., Shirai, K., Sequist, L. V., Rosovsky, R. P., Lilenbaum, R. C., Bastos, B. R., Huang, C., Johnson, M. L., Hesketh, P. J., Subramaniam, D. S., Dietrich, M. F., Chai, F., Wang, Y., Kazakin, J., Schwartz, B., Schiller, J. H., Brahmer, J. R. & 1 others, Kelly, R. J., Mar 1 2018, In : Lung Cancer. 117, p. 44-49 6 p.

Research output: Contribution to journalArticle

4 Scopus citations

Randomized phase III study of docetaxel plus bavituximab in previously treated advanced non-squamous non-small-cell lung cancer

Gerber, D. E., Horn, L., Boyer, M., Sanborn, R., Natale, R., Palmero, R., Bidoli, P., Bondarenko, I., Germonpre, P., Ghizdavescu, D., Kotsakis, A., Lena, H., Losonczy, G., Park, K., Su, W. C., Tang, M., Lai, J., Kallinteris, N. L., Shan, J. S., Reck, M. & 1 others, Spigel, D. R., Jul 1 2018, In : Annals of Oncology. 29, 7, p. 1548-1553 6 p.

Research output: Contribution to journalArticle

7 Scopus citations

Safety and efficacy of concurrent immune checkpoint inhibitors and hypofractionated body radiotherapy

Mohamad, O., Diaz de Leon, A., Schroeder, S., Leiker, A., Christie, A., Zhang-Velten, E., Trivedi, L., Khan, S., Desai, N. B., Laine, A., Albuquerque, K., Iyengar, P., Arriaga, Y., Courtney, K., Gerber, D. E., Hammers, H., Choy, H., Timmerman, R., Brugarolas, J. & Hannan, R., Jul 3 2018, In : OncoImmunology. 7, 7, e1440168.

Research output: Contribution to journalArticle

10 Scopus citations

Statistical justification of expansion cohorts in phase 1 cancer trials

Mokdad, A. A., Xie, X. J., Zhu, H., Gerber, D. E. & Heitjan, D. F., Aug 2018, In : Cancer. 124, 16, p. 3339-3345 7 p.

Research output: Contribution to journalArticle

2 Scopus citations

TNF-driven adaptive response mediates resistance to EGFR inhibition in lung cancer

Gong, K., Guo, G., Gerber, D. E., Gao, B., Peyton, M., Huang, C., Minna, J. D., Hatanpaa, K. J., Kernstine, K., Cai, L., Xie, Y., Zhu, H., Fattah, F. J., Zhang, S., Takahashi, M., Mukherjee, B., Burma, S., Dowell, J., Dao, K., Papadimitrakopoulou, V. A. & 4 others, Olivas, V., Bivona, T. G., Zhao, D. & Habib, A. A., Jun 1 2018, In : Journal of Clinical Investigation. 128, 6, p. 2500-2518 19 p.

Research output: Contribution to journalArticle

16 Scopus citations
2017

A phase ib dose-escalation study of the safety, tolerability, and pharmacokinetics of cobimetinib and duligotuzumab in patients with previously treated locally advanced ormetastatic cancers with mutant KRAS

Lieu, C. H., Hidalgo, M., Berlin, J. D., Ko, A. H., Cervantes, A., LoRusso, P., Gerber, D. E., Paul Eder, J., Gail Eckhardt, S., Kapp, A. V., Tsuhako, A., McCall, B., Pirzkall, A., Uyei, A. & Tabernero, J., Sep 1 2017, In : Oncologist. 22, 9

Research output: Contribution to journalArticle

8 Scopus citations

Cancer center clinic and research team perceptions of identity and interactions

Reimer, T., Lee, S. J. C., Garcia, S., Gill, M., Duncan, T., Williams, E. L. & Gerber, D. E., Dec 1 2017, In : Journal of Oncology Practice. 13, 12, p. e1021-e1029

Research output: Contribution to journalArticle

4 Scopus citations

Histologic transformation of EGFR mutant lung adenocarcinoma without exposure to EGFR inhibition

Le, T., Sailors, J., Oliver, D. H., Mayer, M., Hoskin, S. & Gerber, D. E., Mar 1 2017, In : Lung Cancer. 105, p. 14-16 3 p.

Research output: Contribution to journalArticle

8 Scopus citations

Nivolumab plus ipilimumab as first-line treatment for advanced non-small-cell lung cancer (CheckMate 012): results of an open-label, phase 1, multicohort study

Hellmann, M. D., Rizvi, N. A., Goldman, J. W., Gettinger, S. N., Borghaei, H., Brahmer, J. R., Ready, N. E., Gerber, D. E., Chow, L. Q., Juergens, R. A., Shepherd, F. A., Laurie, S. A., Geese, W. J., Agrawal, S., Young, T. C., Li, X. & Antonia, S. J., Jan 1 2017, In : The Lancet Oncology. 18, 1, p. 31-41 11 p.

Research output: Contribution to journalArticle

434 Scopus citations

Oncology nursing perceptions of patient electronic portal use: A qualitative analysis

Gerber, D. E., Beg, M. S., Duncan, T., Gill, M. & Lee, S. J. C., Mar 1 2017, In : Oncology Nursing Forum. 44, 2, p. 165-170 6 p.

Research output: Contribution to journalArticle

2 Scopus citations

Patient navigation for lung cancer screening in an urban safety-net system: Protocol for a pragmatic randomized clinical trial

Gerber, D. E., Hamann, H. A., Santini, N. O., Abbara, S., Chiu, H., McGuire, M., Quirk, L., Zhu, H. & Lee, S. J. C., Sep 1 2017, In : Contemporary Clinical Trials. 60, p. 78-85 8 p.

Research output: Contribution to journalArticle

6 Scopus citations

Phase 2 study of intermittent pulse dacomitinib in patients with advanced non-small cell lung cancers

Yu, H. A., Ahn, M. J., Cho, B. C., Gerber, D. E., Natale, R. B., Socinski, M. A., Giri, N., Quinn, S., Sbar, E., Zhang, H. & Giaccone, G., Oct 1 2017, In : Lung Cancer. 112, p. 195-199 5 p.

Research output: Contribution to journalArticle

5 Scopus citations

Phase II study of olaratumab with paclitaxel/carboplatin (P/C) or P/C alone in previously untreated advanced NSCLC

Gerber, D. E., Swanson, P., Lopez-Chavez, A., Wong, L., Dowlati, A., Pennell, N. A., Cronier, D. M., Qin, A., Ilaria, R., Cosaert, J., Shahir, A. & Baggstrom, M. Q., Sep 1 2017, In : Lung Cancer. 111, p. 108-115 8 p.

Research output: Contribution to journalArticle

6 Scopus citations