• 2817 Citations
  • 20 h-Index
19982019
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Fingerprint Dive into the research topics where David G McFadden is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 3 Similar Profiles
Basic Helix-Loop-Helix Transcription Factors Medicine & Life Sciences
Thyroid Neoplasms Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Branchial Region Medicine & Life Sciences
Neural Crest Medicine & Life Sciences
Endothelin-1 Medicine & Life Sciences
Limb Buds Medicine & Life Sciences
Transcription Factors Medicine & Life Sciences

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Research Output 1998 2019

  • 2817 Citations
  • 20 h-Index
  • 21 Article
  • 2 Review article

Engineering Forward Genetics into Cultured Cancer Cells for Chemical Target Identification

Povedano, J. M., Liou, J., Wei, D., Srivatsav, A., Kim, J., Xie, Y., Nijhawan, D. & McFadden, D. G., Sep 19 2019, In : Cell Chemical Biology. 26, 9, p. 1315-1321.e3

Research output: Contribution to journalArticle

DNA Mismatch Repair
Genetic Engineering
Cultured Cells
Cells
Repair
1 Citation (Scopus)

Short Review: Genomic Alterations in Hürthle Cell Carcinoma

Ganly, I. & McFadden, D. G., Apr 1 2019, In : Thyroid. 29, 4, p. 471-479 9 p.

Research output: Contribution to journalReview article

Carcinoma
Neoplasms
Exome
RNA Sequence Analysis
Mitochondrial Genome
21 Citations (Scopus)

Widespread Chromosomal Losses and Mitochondrial DNA Alterations as Genetic Drivers in Hürthle Cell Carcinoma

Gopal, R. K., Kübler, K., Calvo, S. E., Polak, P., Livitz, D., Rosebrock, D., Sadow, P. M., Campbell, B., Donovan, S. E., Amin, S., Gigliotti, B. J., Grabarek, Z., Hess, J. M., Stewart, C., Braunstein, L. Z., Arndt, P. F., Mordecai, S., Shih, A. R., Chaves, F., Zhan, T. & 11 others, Lubitz, C. C., Kim, J., Iafrate, A. J., Wirth, L., Parangi, S., Leshchiner, I., Daniels, G. H., Mootha, V. K., Dias-Santagata, D., Getz, G. & McFadden, D. G., Aug 13 2018, In : Cancer Cell. 34, 2, p. 242-255.e5

Research output: Contribution to journalArticle

Mitochondrial DNA
Thyroid Neoplasms
Carcinoma
Electron Transport Complex I
Haploidy
49 Citations (Scopus)

Mutational landscape of EGFR-, MYC-, and Kras-driven genetically engineered mouse models of lung adenocarcinoma

McFadden, D. G., Politi, K., Bhutkar, A., Chen, F. K., Song, X., Pirun, M., Santiago, P. M., Kim-Kiselak, C., Platt, J. T., Lee, E., Hodges, E., Rosebrock, A. P., Bronson, R. T., Socci, N. D., Hannon, G. J., Jacks, T. & Varmus, H., Oct 18 2016, In : Proceedings of the National Academy of Sciences of the United States of America. 113, 42, p. E6409-E6417

Research output: Contribution to journalArticle

Epidermal Growth Factor Receptor
Neoplasms
Mutation
Oncogenes
Adenocarcinoma of lung
61 Citations (Scopus)

Small cell lung cancer: Can recent advances in biology and molecular biology be translated into improved outcomes?

Bunn, P. A., Minna, J. D., Augustyn, A., Gazdar, A. F., Ouadah, Y., Krasnow, M. A., Berns, A., Brambilla, E., Rekhtman, N., Massion, P. P., Niederst, M., Peifer, M., Yokota, J., Govindan, R., Poirier, J. T., Byers, L. A., Wynes, M. W., McFadden, D. G., MacPherson, D., Hann, C. L. & 34 others, Farago, A. F., Dive, C., Teicher, B. A., Peacock, C. D., Johnson, J. E., Cobb, M. H., Wendel, H. G., Spigel, D., Sage, J., Yang, P., Pietanza, M. C., Krug, L. M., Heymach, J., Ujhazy, P., Zhou, C., Goto, K., Dowlati, A., Christensen, C. L., Park, K., Einhorn, L. H., Edelman, M. J., Giaccone, G., Gerber, D. E., Salgia, R., Owonikoko, T., Malik, S., Karachaliou, N., Gandara, D. R., Slotman, B. J., Blackhall, F., Goss, G., Thomas, R., Rudin, C. M. & Hirsch, F. R., 2016, In : Journal of Thoracic Oncology. 11, 4, p. 453-474 22 p.

Research output: Contribution to journalArticle