• 10989 Citations
  • 55 h-Index
1982 …2020

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Article
2020

Global activation of oncogenic pathways underlies therapy resistance in diffuse midline glioma

Georgescu, M. M., Islam, M. Z., Li, Y., Circu, M. L., Traylor, J., Notarianni, C. M., Kline, C. N. & Burns, D. K., Jul 17 2020, In : Acta Neuropathologica Communications. 8, 1, 111.

Research output: Contribution to journalArticle

Open Access
2019

Cell-of-origin susceptibility to glioblastoma formation declines with neural lineage restriction

Alcantara Llaguno, S., Sun, D., Pedraza, A. M., Vera, E., Wang, Z., Burns, D. K. & Parada, L. F., Apr 1 2019, In : Nature neuroscience. 22, 4, p. 545-555 11 p.

Research output: Contribution to journalArticle

13 Scopus citations

Distinct expression patterns of carbonic anhydrase IX in clear cell, microcystic, and angiomatous meningiomas

Chkheidze, R., Cimino, P. J., Hatanpaa, K. J., White, C. L., Ferreira, M., Piccirillo, S. G. M., Li, L., Rajaram, S., Nyagilo, J. O., Burns, D. K., Raisanen, J. M. & Cai, C., Dec 1 2019, In : Journal of neuropathology and experimental neurology. 78, 12, p. 1081-1088 8 p.

Research output: Contribution to journalArticle

1 Scopus citations
2018

BRAF mutation leading to central nervous system rosai-dorfman disease

Richardson, T. E., Wachsmann, M., Oliver, D., Abedin, Z., Ye, D., Burns, D. K., Raisanen, J. M., Greenberg, B. M. & Hatanpaa, K. J., Jul 1 2018, In : Annals of Neurology. 84, 1, p. 147-152 6 p.

Research output: Contribution to journalArticle

6 Scopus citations
3 Scopus citations

Remote acoustic sensing as a safety mechanism during exposure of metal implants to alternating magnetic fields

Cheng, B., Chatzinoff, Y., Szczepanski, D., Bing, C., Shaikh, S., Wyman, O., Perry, C. E., Richardson, J. A., Burns, D. K., Evers, B. M., Greenberg, D. E. & Chopra, R., May 2018, In : PloS one. 13, 5, e0197380.

Research output: Contribution to journalArticle

5 Scopus citations
2017
6 Scopus citations

Assessment of acute thermal damage volumes in muscle using magnetization-prepared 3D T2-weighted imaging following MRI-guided high-intensity focused ultrasound therapy

Staruch, R. M., Nofiele, J., Walker, J., Bing, C., Madhuranthakam, A. J., Bailey, A., Kim, Y. S., Chhabra, A., Burns, D. & Chopra, R., Aug 2017, In : Journal of Magnetic Resonance Imaging. 46, 2, p. 354-364 11 p.

Research output: Contribution to journalArticle

3 Scopus citations

Employing high-frequency alternating magnetic fields for the non-invasive treatment of prosthetic joint infections

Chopra, R., Shaikh, S., Chatzinoff, Y., Munaweera, I., Cheng, B., Daly, S. M., Xi, Y., Bing, C., Burns, D. & Greenberg, D. E., Dec 1 2017, In : Scientific reports. 7, 1, 7520.

Research output: Contribution to journalArticle

12 Scopus citations

High-dose methotrexate with leucovorin rescue: For monumentally severe CNS inflammatory syndromes

Beh, S. C., Kildebeck, E., Narayan, R., Desena, A., Schell, D., Rowe, E. S., Rowe, V., Burns, D. K., Whitworth, L. A., Frohman, T. C., Greenberg, B. & Frohman, E., Jan 15 2017, In : Journal of the Neurological Sciences. 372, p. 187-195 9 p.

Research output: Contribution to journalArticle

6 Scopus citations
3 Scopus citations
2016

Olig2-Dependent Reciprocal Shift in PDGF and EGF Receptor Signaling Regulates Tumor Phenotype and Mitotic Growth in Malignant Glioma

Lu, F., Chen, Y., Zhao, C., Wang, H., He, D., Xu, L., Wang, J., He, X., Deng, Y., Lu, E. E., Liu, X., Verma, R., Bu, H., Drissi, R., Fouladi, M., Stemmer-Rachamimov, A. O., Burns, D., Xin, M., Rubin, J. B., Bahassi, E. M. & 3 others, Canoll, P., Holland, E. C. & Lu, Q. R., May 9 2016, In : Cancer Cell. 29, 5, p. 669-683 15 p.

Research output: Contribution to journalArticle

43 Scopus citations
2015

Adult Lineage-Restricted CNS Progenitors Specify Distinct Glioblastoma Subtypes

Alcantara Llaguno, S. R., Wang, Z., Sun, D., Chen, J., Xu, J., Kim, E., Hatanpaa, K. J., Raisanen, J. M., Burns, D. K., Johnson, J. E. & Parada, L. F., Oct 12 2015, In : Cancer Cell. 28, 4, p. 429-440 12 p., 2152.

Research output: Contribution to journalArticle

82 Scopus citations

A PAX1 enhancer locus is associated with susceptibility to idiopathic scoliosis in females

TSRHC Scoliosis Clinical Group & Japan Scoliosis Clinical Research Group, 2015, In : Nature communications. 6, 6452.

Research output: Contribution to journalArticle

65 Scopus citations

Atypical Presentation for Friedreich Ataxia in a Child

Caron, E., Burns, D., Castro, D. & Iannaccone, S. T., Sep 8 2015, In : Journal of Clinical Neuromuscular Disease. 17, 1, p. 13-17 5 p.

Research output: Contribution to journalArticle

4 Scopus citations
5 Scopus citations

Non-Invasive Targeted Peripheral Nerve Ablation Using 3D MR Neurography and MRI-Guided High-Intensity Focused Ultrasound (MR-HIFU): Pilot Study in a Swine Model

Huisman, M., Staruch, R. M., Ladouceur-Wodzak, M., Van Den Bosch, M. A., Burns, D. K., Chhabra, A. & Chopra, R., Dec 1 2015, In : PloS one. 10, 12, e0144742.

Research output: Contribution to journalArticle

8 Scopus citations

The defining pathology of the new clinical and histopathologic entity ACTA2-related cerebrovascular disease

Georgescu, M. M., Pinho, M. D. C., Richardson, T. E., Torrealba, J., Buja, L. M., Milewicz, D. M., Raisanen, J. M. & Burns, D. K., Dec 4 2015, In : Acta neuropathologica communications. 3, p. 81 1 p.

Research output: Contribution to journalArticle

14 Scopus citations
2014

Expression of MAP 2 by haemangioblastomas: An immunohistochemical study with implications for diagnosis

Malafronte, P. J., LePage, E. M., Hatanpaa, K. J., Burns, D. K., White, C. L. & Raisanen, J., Aug 2014, In : Pathology. 46, 5, p. 450-451 2 p.

Research output: Contribution to journalArticle

Hepatic entrapment of esterified cholesterol drives continual expansion of whole body sterol pool in lysosomal acid lipase-deficient mice

Lopez, A. M., Posey, K. S., Repa, J. J., Turley, S. D., Aqul, A., Taylor, A. M., Repa, J. J., Burns, D. K. & Taylor, A. M., Oct 15 2014, In : American Journal of Physiology - Gastrointestinal and Liver Physiology. 307, 8, p. G836-G847

Research output: Contribution to journalArticle

16 Scopus citations
19 Scopus citations
35 Scopus citations

The G protein α subunit Gαs is a tumor suppressor in Sonic hedgehog-driven medulloblastoma

He, X., Zhang, L., Chen, Y., Remke, M., Shih, D., Lu, F., Wang, H., Deng, Y., Yu, Y., Xia, Y., Wu, X., Ramaswamy, V., Hu, T., Wang, F., Zhou, W., Burns, D. K., Kim, S. H., Kool, M., Pfister, S. M., Weinstein, L. S. & 7 others, Pomeroy, S. L., Gilbertson, R. J., Rubin, J. B., Hou, Y., Wechsler-Reya, R., Taylor, M. D. & Lu, Q. R., Sep 1 2014, In : Nature medicine. 20, 9, p. 1035-1042 8 p.

Research output: Contribution to journalArticle

58 Scopus citations
2013

An elderly woman with difficulty reading and abnormal eye movements

Desestret, V., Streichenberger, N., Panouillères, M., Pélisson, D., Plus, B., Duyckaerts, C., Burns, D. K., Scheiber, C., Vighetto, A. & Tilikete, C., Sep 1 2013, In : Journal of Neuro-Ophthalmology. 33, 3, p. 296-301 6 p.

Research output: Contribution to journalArticle

1 Scopus citations

Progressive leg pain and weakness

Navalkele, D. D., Georgescu, M. M., Burns, D. K., Greenberg, T. & Vernino, S., Apr 2013, In : JAMA neurology. 70, 4, p. 510-514 5 p.

Research output: Contribution to journalArticle

Somatic gain-of-function mutations in PIK3CA in patients with macrodactyly

Rios, J. J., Paria, N., Burns, D. K., Israel, B. A., Cornelia, R., Wise, C. A. & Ezaki, M., Feb 1 2013, In : Human molecular genetics. 22, 3, p. 444-451 8 p., dds440.

Research output: Contribution to journalArticle

87 Scopus citations

TDP-43, an ALS Linked Protein, Regulates Fat Deposition and Glucose Homeostasis

Stallings, N. R., Puttaparthi, K., Dowling, K. J., Luther, C. M., Burns, D. K., Davis, K. & Elliott, J. L., Aug 13 2013, In : PloS one. 8, 8, e71793.

Research output: Contribution to journalArticle

39 Scopus citations
2012

A calcium channel mutant mouse model of hypokalemic periodic paralysis

Wu, F., Mi, W., Hernández-Ochoa, E. O., Burns, D. K., Fu, Y., Gray, H. F., Struyk, A. F., Schneider, M. F. & Cannon, S. C., Dec 3 2012, In : Journal of Clinical Investigation. 122, 12, p. 4580-4591 12 p.

Research output: Contribution to journalArticle

57 Scopus citations

A restricted cell population propagates glioblastoma growth after chemotherapy

Chen, J., Li, Y., Yu, T. S., McKay, R. M., Burns, D. K., Kernie, S. G. & Parada, L. F., Aug 23 2012, In : Nature. 488, 7412, p. 522-526 5 p.

Research output: Contribution to journalArticle

1153 Scopus citations

Solitary Liver Mass in a Patient With Hepatitis C

Renthal, N. E., Tsai, J. P. Y. & Burns, D. K., May 2012, In : Clinical Gastroenterology and Hepatology. 10, 5, p. e46

Research output: Contribution to journalArticle

The nuclear receptor TLX is required for gliomagenesis within the adult neurogenic niche

Zou, Y., Niu, W., Qin, S., Downes, M., Burns, D. K. & Zhang, C. L., Dec 1 2012, In : Molecular and cellular biology. 32, 23, p. 4811-4820 10 p.

Research output: Contribution to journalArticle

25 Scopus citations
2011

A sodium channel knockin mutant (NaV1.4-R669H) mouse model of hypokalemic periodic paralysis

Wu, F., Mi, W., Burns, D. K., Fu, Y., Gray, H. F., Struyk, A. F. & Cannon, S. C., Oct 3 2011, In : Journal of Clinical Investigation. 121, 10, p. 4082-4094 13 p.

Research output: Contribution to journalArticle

47 Scopus citations

Purkinje cell-specific males absent on the first (mMof) gene deletion results in an ataxia-telangiectasia-like neurological phenotype and backward walking in mice

Kumar, R., Hunt, C. R., Gupta, A., Nannepaga, S., Pandita, R. K., Shay, J. W., Bachoo, R., Ludwig, T., Burns, D. K. & Pandita, T. K., Mar 1 2011, In : Proceedings of the National Academy of Sciences of the United States of America. 108, 9, p. 3636-3641 6 p.

Research output: Contribution to journalArticle

34 Scopus citations

Tsc1 mutant neural stem/progenitor cells exhibit migration deficits and give rise to subependymal lesions in the lateral ventricle

Zhou, J., Shrikhande, G., Xu, J., Mckay, R. M., Burns, D. K., Johnson, J. E. & Parada, L. F., Aug 1 2011, In : Genes and Development. 25, 15, p. 1595-1600 6 p.

Research output: Contribution to journalArticle

72 Scopus citations

Unesterified cholesterol accumulation in late endosomes/lysosomes causes neurodegeneration and is prevented by driving cholesterol export from this compartment

Aqul, A., Liu, B., Ramirez, C. M., Pieper, A. A., Estill, S. J., Burns, D. K., Liu, B., Repa, J. J., Turley, S. D. & Dietschy, J. M., Jun 22 2011, In : Journal of Neuroscience. 31, 25, p. 9404-9413 10 p.

Research output: Contribution to journalArticle

97 Scopus citations
2010

Ataxia and progressive encephalopathy in a 4-year-old girl

Spears, M. D., Melton, S. D., Mao, Q., Payne, D., Rakheja, D., Hatanpaa, K. J., Burns, D. K., Sequeiros, J. & Alonso, I., Jan 1 2010, In : Laboratory Medicine. 41, 1, p. 5-9 5 p.

Research output: Contribution to journalArticle

1 Scopus citations

Autoantibody profiles in two patients with non-autoimmune muscle disease implicate a role for gliadin autoreactivity

Olsen, N. J., Prather, H., Li, Q. Z. & Burns, D. K., Mar 1 2010, In : Neuromuscular Disorders. 20, 3, p. 188-191 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Fetal akinesia deformation sequence and neuroaxonal dystrophy without PLA2G6 mutation

Rakheja, D., Uddin, N., Mitui, M., Cope-Yokoyama, S., Hogan, R. N. & Burns, D. K., Nov 1 2010, In : Pediatric and Developmental Pathology. 13, 6, p. 492-496 5 p.

Research output: Contribution to journalArticle

3 Scopus citations

Progressive motor weakness in transgenic mice expressing human TDP-43

Stallings, N. R., Puttaparthi, K., Luther, C. M., Burns, D. K. & Elliott, J. L., Nov 1 2010, In : Neurobiology of Disease. 40, 2, p. 404-414 11 p.

Research output: Contribution to journalArticle

124 Scopus citations

Weekly cyclodextrin administration normalizes cholesterol metabolism in nearly every organ of the niemann-pick type C1 mouse and markedly prolongs life

Ramirez, C. M., Liu, B., Taylor, A. M., Repa, J. J., Burns, D. K., Weinberg, A. G., Turley, S. D. & Dietschy, J. M., Oct 1 2010, In : Pediatric Research. 68, 4, p. 309-315 7 p.

Research output: Contribution to journalArticle

107 Scopus citations
2009

Cell of Origin and Microenvironment Contribution for NF1-Associated Dermal Neurofibromas

Le, L. Q., Shipman, T., Burns, D. K. & Parada, L. F., May 8 2009, In : Cell Stem Cell. 4, 5, p. 453-463 11 p.

Research output: Contribution to journalArticle

109 Scopus citations

Malignant Astrocytomas Originate from Neural Stem/Progenitor Cells in a Somatic Tumor Suppressor Mouse Model

Alcantara Llaguno, S., Chen, J., Kwon, C. H., Jackson, E. L., Li, Y., Burns, D. K., Alvarez-Buylla, A. & Parada, L. F., Jan 6 2009, In : Cancer Cell. 15, 1, p. 45-56 12 p.

Research output: Contribution to journalArticle

405 Scopus citations

Neuroanatomic profile of polyglutamine immunoreactivity inhuntington disease brains

Herndon, E. S., Hladik, C. L., Shang, P., Burns, D. K., Raisanen, J. & White, C. L., Mar 1 2009, In : Journal of neuropathology and experimental neurology. 68, 3, p. 250-261 12 p.

Research output: Contribution to journalArticle

31 Scopus citations
255 Scopus citations
2008

A homoplasmic mtDNA variant can influence the phenotype of the pathogenic m.7472Cins MTTS1 mutation: Are two mutations better than one?

Swalwell, H., Blakely, E. L., Sutton, R., Tonska, K., Elstner, M., He, L., Taivassalo, T., Burns, D. K., Turnbull, D. M., Haller, R. G., Davidson, M. M. & Taylor, R. W., 2008, In : European Journal of Human Genetics. 16, 10, p. 1265-1274 10 p.

Research output: Contribution to journalArticle

27 Scopus citations

Induction of Abnormal Proliferation by Nonmyelinating Schwann Cells Triggers Neurofibroma Formation

Zheng, H., Chang, L., Patel, N., Yang, J., Lowe, L., Burns, D. K. & Zhu, Y., Feb 5 2008, In : Cancer Cell. 13, 2, p. 117-128 12 p.

Research output: Contribution to journalArticle

100 Scopus citations

Nf1-Dependent Tumors Require a Microenvironment Containing Nf1+/-- and c-kit-Dependent Bone Marrow

Yang, F. C., Ingram, D. A., Chen, S., Zhu, Y., Yuan, J., Li, X., Yang, X., Knowles, S., Horn, W., Li, Y., Zhang, S., Yang, Y., Vakili, S. T., Yu, M., Burns, D., Robertson, K., Hutchins, G., Parada, L. F. & Clapp, D. W., Oct 31 2008, In : Cell. 135, 3, p. 437-448 12 p.

Research output: Contribution to journalArticle

243 Scopus citations

Pten haploinsufficiency accelerates formation of high-grade astrocytomas

Kwon, C. H., Zhao, D., Chen, J., Alcantara, S., Li, Y., Burns, D. K., Mason, R. P., Lee, E. Y. H. P., Wu, H. & Parada, L. F., May 1 2008, In : Cancer research. 68, 9, p. 3286-3294 9 p.

Research output: Contribution to journalArticle

174 Scopus citations
2007

HSV-1 ICP34.5 Confers Neurovirulence by Targeting the Beclin 1 Autophagy Protein

Orvedahl, A., Alexander, D., Tallóczy, Z., Sun, Q., Wei, Y., Zhang, W., Burns, D., Leib, D. A. & Levine, B., Mar 15 2007, In : Cell Host and Microbe. 1, 1, p. 23-35 13 p.

Research output: Contribution to journalArticle

548 Scopus citations

The werner syndrome helicase is a cofactor for HIV-1 long terminal repeat transactivation and retroviral replication

Sharma, A., Awasthi, S., Harrod, C. K., Matlock, E. F., Khan, S., Xu, L., Chan, S., Yang, H., Thammavaram, C. K., Rasor, R. A., Burns, D. K., Skiest, D. J., Van Lint, C., Girard, A. M., McGee, M., Monnat, R. J. & Harrod, R., Apr 20 2007, In : Journal of Biological Chemistry. 282, 16, p. 12048-12057 10 p.

Research output: Contribution to journalArticle

18 Scopus citations