• 1328 Citations
  • 15 h-Index
20062019

Research output per year

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Research Output

High-order epistasis in catalytic power of dihydrofolate reductase gives rise to a rugged fitness landscape in the presence of trimethoprim selection

Tamer, Y. T., Gaszek, I. K., Abdizadeh, H., Batur, T. A., Reynolds, K. A., Atilgan, A. R., Atilgan, C. & Toprak, E., Jan 1 2019, In : Molecular biology and evolution. 36, 7, p. 1533-1550 18 p.

Research output: Contribution to journalArticle

Open Access
  • 1 Scopus citations

    Non-antibiotic Small-Molecule Regulation of DHFR-Based Destabilizing Domains In Vivo

    Peng, H., Chau, V. Q., Phetsang, W., Sebastian, R. M., Stone, M. R. L., Datta, S., Renwick, M., Tamer, Y. T., Toprak, E., Koh, A., Blaskovich, M. A. T. & Hulleman, J. D., Dec 13 2019, In : Molecular Therapy - Methods and Clinical Development. 15, p. 27-39 13 p.

    Research output: Contribution to journalArticle

    Open Access
  • Rapid ultrasensitive detection platform for antimicrobial susceptibility testing

    Cansizoglu, M. F., Tamer, Y. T., Farid, M., Koh, A. & Toprak, E., May 1 2019, In : PLoS biology. 17, 5, p. e3000291

    Research output: Contribution to journalArticle

    Open Access
  • 3 Scopus citations

    Fighting against evolution of antibiotic resistance by utilizing evolvable antimicrobial drugs

    Cansizoglu, M. F. & Toprak, E., May 11 2017, (Accepted/In press) In : Current Genetics. p. 1-4 4 p.

    Research output: Contribution to journalArticle

  • 12 Scopus citations

    Increased substrate affinity in the Escherichia coli L28R dihydrofolate reductase mutant causes trimethoprim resistance

    Abdizadeh, H., Tamer, Y. T., Acar, O., Toprak, E., Atilgan, A. R. & Atilgan, C., 2017, In : Physical Chemistry Chemical Physics. 19, 18, p. 11416-11428 13 p.

    Research output: Contribution to journalArticle

  • 7 Scopus citations