• 32756 Citations
  • 87 h-Index
1976 …2019
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Fingerprint Dive into the research topics where Melanie H Cobb is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 9 Similar Profiles
Phosphotransferases Medicine & Life Sciences
Protein Kinases Medicine & Life Sciences
Mitogen-Activated Protein Kinases Medicine & Life Sciences
Phosphorylation Medicine & Life Sciences
Chemical activation Chemical Compounds
Mitogen-Activated Protein Kinase 1 Medicine & Life Sciences
Insulin Medicine & Life Sciences
Mitogen-Activated Protein Kinase 3 Medicine & Life Sciences

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Research Output 1976 2019

  • 32756 Citations
  • 87 h-Index
  • 266 Article
  • 2 Review article
  • 1 Short survey

Functional divergence caused by mutations in an energetic hotspot in ERK2

Taylor, C. A., Cormier, K. W., Keenan, S. E., Earnest, S., Stippec, S., Wichaidit, C., Juang, Y. C., Wang, J., Shvartsman, S. Y., Goldsmith, E. J. & Cobb, M. H., Jul 30 2019, In : Proceedings of the National Academy of Sciences of the United States of America. 116, 31, p. 15514-15523 10 p.

Research output: Contribution to journalArticle

Open Access
Mitogen-Activated Protein Kinase 1
Mutation
Hot Temperature
Dual-Specificity Phosphatases
Neoplasms

Measuring relative insulin secretion using a co-secreted luciferase surrogate

Kalwat, M. & Cobb, M. H., Jun 1 2019, In : Journal of Visualized Experiments. 2019, 148, e59926.

Research output: Contribution to journalArticle

Insulin
Luciferases
Assays
C-Peptide
Antibodies

Subtype-specific secretomic characterization of pulmonary neuroendocrine tumor cells

Wang, X. D., Hu, R., Ding, Q., Savage, T. K., Huffman, K. E., Williams, N. S., Cobb, M. H., Minna, J. D., Johnson, J. E. & Yu, Y., Dec 1 2019, In : Nature communications. 10, 1, 3201.

Research output: Contribution to journalArticle

Open Access
Neuroendocrine Cells
Neuroendocrine Tumors
Small Cell Lung Carcinoma
Tumors
Lung Neoplasms

Chromomycin A2 potently inhibits glucosestimulated insulin secretion from pancreatic β cells

Kalwat, M. A., Hwang, I. H., Macho, J., Grzemska, M. G., Yang, J. Z., McGlynn, K., MacMillan, J. B. & Cobb, M. H., Dec 1 2018, In : Journal of General Physiology. 150, 12, p. 1747-1757 11 p.

Research output: Contribution to journalArticle

Insulin
Plicamycin
Glucose
Biological Products
Islets of Langerhans
20 Citations (Scopus)

Enteroid Monolayers Reveal an Autonomous WNT and BMP Circuit Controlling Intestinal Epithelial Growth and Organization

Thorne, C. A., Chen, I. W., Sanman, L. E., Cobb, M. H., Wu, L. F. & Altschuler, S. J., Mar 12 2018, In : Developmental Cell. 44, 5, p. 624-633.e4

Research output: Contribution to journalArticle

Intestinal Mucosa
Monolayers
Tissue
Networks (circuits)
Growth