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Research Output 1998 2019

  • 1021 Citations
  • 10 h-Index
  • 22 Article
  • 1 Chapter
  • 1 Short survey
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Article
2019

Hand2 Selectively Reorganizes Chromatin Accessibility to Induce Pacemaker-like Transcriptional Reprogramming

Fernandez-Perez, A., Sathe, A. A., Bhakta, M., Leggett, K., Xing, C. & Munshi, N. V., May 21 2019, In : Cell Reports. 27, 8, p. 2354-2369.e7

Research output: Contribution to journalArticle

Open Access
Pacemakers
Muscle Cells
Chromatin
Desmosomes
Sarcomeres

PAN-INTACT enables direct isolation of lineage-specific nuclei from fibrous tissues

Bhattacharyya, S., Sathe, A. A., Bhakta, M., Xing, C. & Munshi, N. V., Apr 1 2019, In : PloS one. 14, 4, e0214677.

Research output: Contribution to journalArticle

Open Access
Tissue
Chromatin
Transposases
Endothelial cells
cells
1 Citation (Scopus)

Rational Reprogramming of Cellular States by Combinatorial Perturbation

Duan, J., Li, B., Bhakta, M., Xie, S., Zhou, P., Munshi, N. V. & Hon, G., Jun 18 2019, In : Cell Reports. 27, 12, p. 3486-3499.e6

Research output: Contribution to journalArticle

Open Access
Transcription Factors
Regenerative Medicine
Libraries
Cellular Reprogramming
Atlases

Using Gjd3-CreEGFP mice to examine atrioventricular node morphology and composition

Bhattacharyya, S., Duan, J., Wang, L., Li, B., Bhakta, M., Fernandez-Perez, A., Hon, G. & Munshi, N. V., Dec 1 2019, In : Scientific Reports. 9, 1, 2106.

Research output: Contribution to journalArticle

Atrioventricular Node
Microdissection
Atlases
Cardiac Myocytes
Confocal Microscopy
2018

Functional cargo delivery into mouse and human fibroblasts using a versatile microfluidic device

Lam, K. H., Fernandez-Perez, A., Schmidtke, D. W. & Munshi, N. V., Sep 1 2018, In : Biomedical Microdevices. 20, 3, 52.

Research output: Contribution to journalArticle

Lab-On-A-Chip Devices
Polydimethylsiloxane
Fibroblasts
Microfluidics
Costs and Cost Analysis

High content analysis identifies unique morphological features of reprogrammed cardiomyocytes

Sutcliffe, M. D., Tan, P. M., Fernandez-Perez, A., Nam, Y. J., Munshi, N. V. & Saucerman, J. J., Dec 1 2018, In : Scientific Reports. 8, 1, 1258.

Research output: Contribution to journalArticle

Cardiac Myocytes
Sarcomeres
Cell Shape
Gene Expression Profiling
Cell Size

pouC Regulates Expression of bmp4 During Atrioventricular Canal Formation in Zebrafish

Bhakta, M., Padanad, M. S., Harris, J. P., Lubczyk, C., Amatruda, J. F. & Munshi, N. V., Jan 1 2018, (Accepted/In press) In : Developmental Dynamics.

Research output: Contribution to journalArticle

Zebrafish
Morphogenesis
Heart Diseases
POU Domain Factors
Cardiac Myocytes
2017
3 Citations (Scopus)

Assessing cardiomyocyte subtypes following transcription factor-mediated reprogramming of mouse embryonic fibroblasts

Fernandez-Perez, A. & Munshi, N. V., Mar 22 2017, In : Journal of Visualized Experiments. 2017, 121, e55456.

Research output: Contribution to journalArticle

Transcription factors
Fibroblasts
Cardiac Myocytes
Transcription Factors
Muscle Cells
4 Citations (Scopus)

Phenotypically silent Cre recombination within the postnatal ventricular conduction system

Bhattacharyya, S., Bhakta, M. & Vilas Munshi, N., Mar 1 2017, In : PLoS One. 12, 3, e0174517.

Research output: Contribution to journalArticle

Untranslated Regions
Genetic Recombination
mice
position effect (genetics)
3' Untranslated Regions
1 Citation (Scopus)

The promise of cardiac regeneration by in situ lineage conversion

Nam, Y. J. & Munshi, N. V., Mar 7 2017, In : Circulation. 135, 10, p. 914-916 3 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Regeneration
Fibroblasts
Myocardial Infarction
Cicatrix
2016
4 Citations (Scopus)

CRISPR (Clustered Regularly Interspaced Palindromic Repeat)/Cas9 System: A Revolutionary Disease-Modifying Technology

Munshi, N. V., Sep 13 2016, In : Circulation. 134, 11, p. 777-779 3 p.

Research output: Contribution to journalArticle

2015
4 Citations (Scopus)

MyoR modulates cardiac conduction by repressing Gata4

Harris, J. P., Bhakta, M., Bezprozvannaya, S., Wang, L., Lubczyk, C., Olson, E. N. & Munshi, N. V., 2015, In : Molecular and Cellular Biology. 35, 4, p. 649-661 13 p.

Research output: Contribution to journalArticle

Atrioventricular Node
Transcription Factors
Gene Expression
Population
2014
11 Citations (Scopus)

Improving cardiac rhythm with a biological pacemaker

Munshi, N. V. & Olson, E. N., 2014, In : Science. 345, 6194, p. 268-269 2 p.

Research output: Contribution to journalArticle

cardiology
disease treatment
Biological Clocks
electronic equipment
Heart Block
69 Citations (Scopus)

Induction of diverse cardiac cell types by reprogramming fibroblasts with cardiac transcription factors

Nam, Y. J., Lubczyk, C., Bhakta, M., Zang, T., Fernandez-Perez, A., McAnally, J., Bassel-Duby, R., Olson, E. N. & Munshi, N. V., Nov 1 2014, In : Development (Cambridge). 141, 22, p. 4267-4278 12 p.

Research output: Contribution to journalArticle

Cardiac Myocytes
Transcription Factors
Fibroblasts
Phenotype
Stem Cells
2012
50 Citations (Scopus)

Gene regulatory networks in cardiac conduction system development

Munshi, N. V., May 25 2012, In : Circulation Research. 110, 11, p. 1525-1537 13 p.

Research output: Contribution to journalArticle

Gene Regulatory Networks
Genetic Techniques
Cardiac Myocytes
Muscle Cells
Cardiac Arrhythmias
2009
45 Citations (Scopus)

Cx30.2 enhancer analysis identifies Gata4 as a novel regulator of atrioventricular delay

Munshi, N. V., McAnally, J., Bezprozvannaya, S., Berry, J. M., Richardson, J. A., Hill, J. A. & Olson, E. N., Aug 1 2009, In : Development. 136, 15, p. 2665-2674 10 p.

Research output: Contribution to journalArticle

Connexins
Regulator Genes
Cardiac Myocytes
Cardiac Arrhythmias
Genes
2001
168 Citations (Scopus)

Coordination of a transcriptional switch by HMGI(Y) acetylation

Munshi, N., Agalioti, T., Lomvardas, S., Merika, M., Chen, G. & Thanos, D., Aug 10 2001, In : Science. 293, 5532, p. 1133-1136 4 p.

Research output: Contribution to journalArticle

CREB-Binding Protein
Acetylation
Lysine
Interferons
HMGA1a Protein
2000
133 Citations (Scopus)

An Ikaros-containing chromatin-remodeling complex in adult-type erythroid cells

O'Neill, D. W., Schoetz, S. S., Lopez, R. A., Castle, M., Rabinowitz, L., Shor, E., Krawchuk, D., Goll, M. G., Renz, M., Seelig, H. P., Han, S., Seong, R. H., Park, S. D., Agalioti, T., Munshi, N., Thanos, D., Erdjument-Bromage, H., Tempst, P. & Bank, A., 2000, In : Molecular and Cellular Biology. 20, 20, p. 7572-7582 11 p.

Research output: Contribution to journalArticle

Erythroid Cells
Chromatin Assembly and Disassembly
Globins
Nucleosomes
Mi-2 Nucleosome Remodeling and Deacetylase Complex
36 Citations (Scopus)

The architectural transcription factor high mobility group I(Y) participates in photoreceptor-specific gene expression

Chau, K. Y., Munshi, N., Keane-Myers, A., Cheung-Chau, K. W., Kwong-Fuk Tai, A., Manfioletti, G., Dorey, C. K., Thanos, D., Zack, D. J. & Ono, S. J., Oct 1 2000, In : Journal of Neuroscience. 20, 19, p. 7317-7324 8 p.

Research output: Contribution to journalArticle

Transcription Factors
Gene Expression
Rhodopsin
HMGA1a Protein
Proteins
1999
56 Citations (Scopus)

The IFN-β enhancer: A paradigm for understanding activation and repression of inducible gene expression

Munshi, N., Yie, J., Merika, M., Senger, K., Lomvardas, S., Agalioti, T. & Thanos, D., 1999, In : Cold Spring Harbor Symposia on Quantitative Biology. 64, p. 149-159 11 p.

Research output: Contribution to journalArticle

TFII Transcription Factors
Gene expression regulation
DNA Polymerase II
Transcription Factor TFIID
High Mobility Group Proteins
142 Citations (Scopus)

The role of HMG I(Y) in the assembly and function of the IFN-β enhanceosome

Yie, J., Merika, M., Munshi, N., Chen, G. & Thanos, D., Jun 1 1999, In : EMBO Journal. 18, 11, p. 3074-3089 16 p.

Research output: Contribution to journalArticle

HMGA1a Protein
Interferons
Transcription
Proteins
Nucleoproteins
1998
293 Citations (Scopus)

Acetylation of HMG I(Y) by CBP turns off IFNβ expression by disrupting the enhanceosome

Munshi, N., Merika, M., Yie, J., Senger, K., Chen, G. & Thanos, D., Oct 1998, In : Molecular Cell. 2, 4, p. 457-467 11 p.

Research output: Contribution to journalArticle

Acetylation
Virus Activation
Acetyltransferases
Transcriptional Activation
Lysine