Pradeep P Mammen

  • 2616 Citations
  • 26 h-Index
19952019

Research output per year

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Research Output

  • 2616 Citations
  • 26 h-Index
  • 53 Article
  • 3 Chapter
  • 1 Conference contribution
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Article
2019

CRISPR-Cas9 corrects Duchenne muscular dystrophy exon 44 deletion mutations in mice and human cells

Min, Y. L., Li, H., Rodriguez-Caycedo, C., Mireault, A. A., Huang, J., Shelton, J. M., McAnally, J. R., Amoasii, L., Mammen, P. P., Bassel-Duby, R. S. & Olson, E. N., Jan 1 2019, In : Science Advances. 5, 3, eaav4324.

Research output: Contribution to journalArticle

Open Access
15 Scopus citations

Nitrosative stress drives heart failure with preserved ejection fraction

Schiattarella, G. G., Altamirano, F., Tong, D., French, K. M., Villalobos, E., Kim, S. Y., Luo, X., Jiang, N., May, H. I., Wang, Z., Hill, T. M., Mammen, P. P., Huang, J., Lee, D. I., Hahn, V. S., Sharma, K., Kass, D. A., Lavandero, S., Gillette, T. G. & Hill, J. A., Apr 18 2019, In : Nature. 568, 7752, p. 351-356 6 p.

Research output: Contribution to journalArticle

35 Scopus citations
2018

Correction of diverse muscular dystrophy mutations in human engineered heart muscle by single-site genome editing

Long, C., Li, H., Tiburcy, M., Rodriguez-Caycedo, C., Kyrychenko, V., Zhou, H., Zhang, Y., Min, Y. L., Shelton, J. M., Mammen, P. P. A., Liaw, N. Y., Zimmermann, W. H., Bassel-Duby, R., Schneider, J. W. & Olson, E. N., Jan 1 2018, In : Science advances. 4, 1, eaap9004.

Research output: Contribution to journalArticle

44 Scopus citations
2017

Bendopnea and risk of adverse clinical outcomes in ambulatory patients with systolic heart failure

Thibodeau, J. T., Jenny, B. E., Maduka, J. O., Divanji, P. H., Ayers, C. R., Araj, F., Amin, A. A., Morlend, R. M., Mammen, P. P. A. & Drazner, M. H., Jan 1 2017, In : American Heart Journal. 183, p. 102-107 6 p.

Research output: Contribution to journalArticle

11 Scopus citations
23 Scopus citations

Fuchs’ endothelial corneal dystrophy and RNA foci in patients with myotonic dystrophy

Mootha, V., Hansen, B., Rong, Z., Mammen, P. P., Zhou, Z., Xing, C. & Gong, X., Sep 1 2017, In : Investigative Ophthalmology and Visual Science. 58, 11, p. 4579-4585 7 p.

Research output: Contribution to journalArticle

15 Scopus citations
8 Scopus citations

Induction regimen and survival in simultaneous heart-kidney transplant recipients

Ariyamuthu, V. K., Amin, A. A., Drazner, M. H., Araj, F., Mammen, P. P. A., Ayvaci, M., Mete, M., Ozay, F., Ghanta, M., Mohan, S., Mohan, P. & Tanriover, B., Jan 1 2017, (Accepted/In press) In : Journal of Heart and Lung Transplantation.

Research output: Contribution to journalArticle

2 Scopus citations
9 Scopus citations
2015

Human ventricular unloading induces cardiomyocyte proliferation

Canseco, D. C., Kimura, W., Garg, S., Mukherjee, S., Bhattacharya, S., Abdisalaam, S., Das, S., Asaithamby, A., Mammen, P. P. A. & Sadek, H. A., Mar 10 2015, In : Journal of the American College of Cardiology. 65, 9, p. 892-900 9 p.

Research output: Contribution to journalArticle

59 Scopus citations
2014

Characterization of a Novel Symptom of Advanced Heart Failure: Bendopnea

Thibodeau, J. T., Turer, A. T., Gualano, S. K., Ayers, C. R., Velez-Martinez, M., Mishkin, J. D., Patel, P. C., Mammen, P. P. A., Markham, D. W., Levine, B. D. & Drazner, M. H., Feb 2014, In : JACC: Heart Failure. 2, 1, p. 24-31 8 p.

Research output: Contribution to journalArticle

51 Scopus citations

Cytoglobin modulates myogenic progenitor cell viability and muscle regeneration

Singh, S., Canseco, D. C., Manda, S. M., Shelton, J. M., Chirumamilla, R. R., Goetsch, S. C., Ye, Q., Gerard, R. D., Schneider, J. W., Richardson, J. A., Rothermel, B. A. & Mammen, P. P. A., 2014, In : Proceedings of the National Academy of Sciences of the United States of America. 111, 1

Research output: Contribution to journalArticle

33 Scopus citations

High-sensitivity cardiac troponin i assay to screen for acute rejection in patients with heart transplant

Patel, P. C., Hill, D. A., Ayers, C. R., Lavingia, B., Kaiser, P., Dyer, A. K., Barnes, A. P., Thibodeau, J. T., Mishkin, J. D., Mammen, P. P., Markham, D. W., Stastny, P., Ring, W. S., de Lemos, J. A. & Drazner, M. H., 2014, In : Circulation: Heart Failure. 7, 3, p. 463-469 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Spliced X-box binding protein 1 couples the unfolded protein response to hexosamine biosynthetic pathway

Wang, Z., Deng, Y., Gao, N., Pedrozo, Z., Li, D. L., Morales, C. R., Criollo, A., Luo, X., Tan, W., Jiang, N., Lehrman, M. A., Rothermel, B. A., Lee, A. H., Lavandero, S., Mammen, P. P., Ferdous, A., Gillette, T. G., Scherer, P. E. & Hill, J. A., Mar 13 2014, In : Cell. 156, 6, p. 1179-1192 14 p.

Research output: Contribution to journalArticle

141 Scopus citations

Variation of heart transplant rates in the United States during holidays

Grodin, J. L., Ayers, C. R., Thibodeau, J. T., Mishkin, J. D., Mammen, P. P. A., Markham, D. W., Drazner, M. H. & Patel, P. C., 2014, In : Clinical Transplantation. 28, 8, p. 877-882 6 p.

Research output: Contribution to journalArticle

1 Scopus citations
2013

Health insurance as a requirement to undergo cardiac transplantation: A national survey of transplant program practices

Thibodeau, J. T., Rao, M. P., Gupta, C., Ayers, C. R., Gupta, S., Mammen, P. P. A., Markham, D. W., Mishkin, J. D., Patel, P. C., King, L. P. & Drazner, M. H., Jan 2013, In : Transplantation Proceedings. 45, 1, p. 360-363 4 p.

Research output: Contribution to journalArticle

10 Scopus citations

Mice Deficient in the Respiratory Chain Gene Cox6a2 Are Protected against High-Fat Diet-Induced Obesity and Insulin Resistance

Quintens, R., Singh, S., Lemaire, K., de Bock, K., Granvik, M., Schraenen, A., Vroegrijk, I. O. C. M., Costa, V., van Noten, P., Lambrechts, D., Lehnert, S., van Lommel, L., Thorrez, L., de Faudeur, G., Romijn, J. A., Shelton, J. M., Scorrano, L., Lijnen, H. R., Voshol, P. J., Carmeliet, P. & 2 others, Mammen, P. P. A. & Schuit, F., Feb 27 2013, In : PLoS One. 8, 2, e56719.

Research output: Contribution to journalArticle

36 Scopus citations

Pulmonary veins in the normal lung and pulmonary hypertension due to left heart disease

Hunt, J. M., Bethea, B., Liu, X., Gandjeva, A., Mammen, P. P. A., Stacher, E., Gandjeva, M. R., Parish, E., Perez, M., Smith, L., Graham, B. B., Kuebler, W. M. & Tuder, R. M., Nov 15 2013, In : American Journal of Physiology - Lung Cellular and Molecular Physiology. 305, 10

Research output: Contribution to journalArticle

20 Scopus citations

Regulation of neonatal and adult mammalian heart regeneration by the miR-15 family

Porrello, E. R., Mahmoud, A. I., Simpson, E., Johnson, B. A., Grinsfelder, D., Canseco, D., Mammen, P. P., Rothermel, B. A., Olson, E. N. & Sadek, H. A., Jan 2 2013, In : Proceedings of the National Academy of Sciences of the United States of America. 110, 1, p. 187-192 6 p.

Research output: Contribution to journalArticle

331 Scopus citations

Relationship of right- to left-sided ventricular filling pressures in advanced heart failure insights from the escape trial

Drazner, M. H., Velez-Martinez, M., Ayers, C. R., Reimold, S. C., Thibodeau, J. T., Mishkin, J. D., Mammen, P. P. A., Markham, D. W. & Patel, C. B., Mar 2013, In : Circulation: Heart Failure. 6, 2, p. 264-270 7 p.

Research output: Contribution to journalArticle

47 Scopus citations

Tolerability of sirolimus: A decade of experience at a single cardiac transplant center

Thibodeau, J. T., Mishkin, J. D., Patel, P. C., Kaiser, P. A., Ayers, C. R., Mammen, P. P. A., Markham, D. W., Ring, W. S., Peltz, M. & Drazner, M. H., Nov 2013, In : Clinical Transplantation. 27, 6, p. 945-952 8 p.

Research output: Contribution to journalArticle

6 Scopus citations
2012

IIIB or not IIIB: A previously unanswered question

Thibodeau, J. T., Mishkin, J. D., Patel, P. C., Mammen, P. P. A., Markham, D. W. & Drazner, M. H., May 2012, In : Journal of Cardiac Failure. 18, 5, p. 367-372 6 p.

Research output: Contribution to journalArticle

3 Scopus citations

Sirolimus use and incidence of venous thromboembolism in cardiac transplant recipients

Thibodeau, J. T., Mishkin, J. D., Patel, P. C., Kaiser, P. A., Ayers, C. R., Mammen, P. P. A., Markham, D. W., Ring, W. S., Peltz, M. & Drazner, M. H., Nov 2012, In : Clinical Transplantation. 26, 6, p. 953-959 7 p.

Research output: Contribution to journalArticle

13 Scopus citations

The natural history of new-onset heart failure with a severely depressed left ventricular ejection fraction: Implications for timing of implantable cardioverter-defibrillator implantation

Teeter, W. A., Thibodeau, J. T., Rao, K., Brickner, M. E., Toto, K. H., Nelson, L. L., Mishkin, J. D., Ayers, C. R., Miller, J. G., Mammen, P. P. A., Patel, P. C., Markham, D. W. & Drazner, M. H., Sep 2012, In : American Heart Journal. 164, 3, p. 358-364 7 p.

Research output: Contribution to journalArticle

22 Scopus citations

Utilization of cardiac computed tomography angiography for the diagnosis of left ventricular assist device thrombosis

Mishkin, J. D., Enriquez, J. R., Meyer, D. M., Bethea, B. T., Thibodeau, J. T., Patel, P. C., Markham, D. W., Mammen, P. P. A., Velez-Martinez, M. & Drazner, M. H., Mar 2012, In : Circulation: Heart Failure. 5, 2

Research output: Contribution to journalArticle

25 Scopus citations
2011

Successful use of the Tandem Heart percutaneous ventricular assist device as a bridge to recovery for acute cellular rejection in a cardiac transplant patient

Velez-Martinez, M., Rao, K., Warner, J., Dimaio, J., Ewing, G., Mishkin, J. D., Mammen, P. P. A., Drazner, M. H., Markham, D. W. & Patel, P. C., Dec 2011, In : Transplantation Proceedings. 43, 10, p. 3882-3884 3 p.

Research output: Contribution to journalArticle

7 Scopus citations
2010

Clinical outcomes after cardiac transplantation in muscular dystrophy patients

Wu, R. S., Gupta, S., Brown, R. N., Yancy, C. W., Wald, J. W., Kaiser, P., Kirklin, N. M., Patel, P. C., Markham, D. W., Drazner, M. H., Garry, D. J. & Mammen, P. P. A., Apr 2010, In : Journal of Heart and Lung Transplantation. 29, 4, p. 432-438 7 p.

Research output: Contribution to journalArticle

51 Scopus citations

Concentric left ventricular hypertrophy as assessed by cardiac magnetic resonance imaging and risk of death in cardiac transplant recipients

Patel, P. C., Reimold, S. C., Araj, F. G., Ayers, C. R., Kaiser, P. A., Peshock, R. M., Yancy, C. W., Ring, W. S., Gupta, S., Mishkin, J. D., Mammen, P. P., Markham, D. W. & Drazner, M. H., Dec 2010, In : Journal of Heart and Lung Transplantation. 29, 12, p. 1369-1379 11 p.

Research output: Contribution to journalArticle

10 Scopus citations

Regulation of myoglobin expression

Kanatous, S. B. & Mammen, P. P. A., Aug 2010, In : Journal of Experimental Biology. 213, 16, p. 2741-2747 7 p.

Research output: Contribution to journalArticle

57 Scopus citations
2009

Association of cystatin C with left ventricular structure and function: The Dallas Heart Study

Patel, P. C., Ayers, C. R., Murphy, S. A., Peshock, R. M., Khera, A., de Lemos, J. A., Balko, J. A., Gupta, S., Mammen, P. P., Drazner, M. H. & Markham, D. W., Mar 2009, In : Circulation: Heart Failure. 2, 2, p. 98-104 7 p.

Research output: Contribution to journalArticle

81 Scopus citations

Calcineurin activates cytoglobin transcription in hypoxic myocytes

Singh, S., Manda, S. M., Sikder, D., Birrer, M. J., Rothermel, B. A., Garry, D. J. & Mammen, P. P. A., Apr 17 2009, In : Journal of Biological Chemistry. 284, 16, p. 10409-10421 13 p.

Research output: Contribution to journalArticle

25 Scopus citations

Hypoxia reprograms calcium signaling and regulates myoglobin expression

Kanatous, S. B., Mammen, P. P. A., Rosenberg, P. B., Martin, C. M., White, M. D., DiMaio, J. M., Huang, G., Muallem, S. & Garry, D. J., Mar 2009, In : American Journal of Physiology - Cell Physiology. 296, 3

Research output: Contribution to journalArticle

56 Scopus citations

Pancreatic Gout Masquerading as Pancreatic Cancer in a Heart Transplant Candidate

Gupta, S., McMahan, Z., Patel, P. C., Markham, D. W., Drazner, M. H. & Mammen, P. P. A., Oct 2009, In : Journal of Heart and Lung Transplantation. 28, 10, p. 1112-1113 2 p.

Research output: Contribution to journalArticle

9 Scopus citations

Utility of Routine Immunofluorescence Staining for C4d in Cardiac Transplant Recipients

Gupta, S., Mitchell, J. D., Lavingia, B., Ewing, G. E., Feliciano, M. N., Kaiser, P. A., Ring, W. S., Stastny, P., Patel, P. C., Markham, D. W., Mammen, P. P. A., DiMaio, J. M. & Drazner, M. H., Aug 2009, In : Journal of Heart and Lung Transplantation. 28, 8, p. 776-780 5 p.

Research output: Contribution to journalArticle

14 Scopus citations
2008

Fulminant myocarditis

Gupta, S., Markham, D. W., Drazner, M. H. & Mammen, P. P. A., 2008, In : Nature Clinical Practice Cardiovascular Medicine. 5, 11, p. 693-706 14 p.

Research output: Contribution to journalArticle

116 Scopus citations

High Incidence of Cytomegalovirus Disease in D+/R- Heart Transplant Recipients Shortly After Completion of 3 Months of Valganciclovir Prophylaxis

Gupta, S., Mitchell, J. D., Markham, D. W., Mammen, P. P. A., Patel, P. C., Kaiser, P., Ring, W. S., DiMaio, J. M. & Drazner, M. H., May 2008, In : Journal of Heart and Lung Transplantation. 27, 5, p. 536-539 4 p.

Research output: Contribution to journalArticle

26 Scopus citations

Long-term follow-up of a heart transplant recipient with documented seroconversion to HIV-positive status 1 year after transplant

Gupta, S., Markham, D. W., Mammen, P. P. A., Kaiser, P., Patel, P., Ring, W. S. & Drazner, M. H., Apr 2008, In : American Journal of Transplantation. 8, 4, p. 893-896 4 p.

Research output: Contribution to journalArticle

14 Scopus citations

Utility of the Cylex Assay in Cardiac Transplant Recipients

Gupta, S., Mitchell, J. D., Markham, D. W., Mammen, P. P. A., Patel, P. C., Kaiser, P. A., Stastny, P., Ring, W. S., DiMaio, J. M. & Drazner, M. H., Aug 2008, In : Journal of Heart and Lung Transplantation. 27, 8, p. 817-822 6 p.

Research output: Contribution to journalArticle

27 Scopus citations
2006

Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain

Mammen, P. P. A., Shelton, J. M., Ye, Q., Kanatous, S. B., McGrath, A. J., Richardson, J. A. & Garry, D. J., Dec 2006, In : Journal of Histochemistry and Cytochemistry. 54, 12, p. 1349-1361 13 p.

Research output: Contribution to journalArticle

43 Scopus citations
2005

Alternative therapies for orthotopic heart transplantation

Garry, D. J., Goetsch, S. C., McGrath, A. J. & Mammen, P. P. A., Aug 2005, In : American Journal of the Medical Sciences. 330, 2, p. 88-101 14 p.

Research output: Contribution to journalArticle

3 Scopus citations

LXRs regulate the balance between fat storage and oxidation

Kalaany, N. Y., Gauthier, K. C., Zavacki, A. M., Mammen, P. P. A., Kitazume, T., Peterson, J. A., Horton, J. D., Garry, D. J., Bianco, A. C. & Mangelsdorf, D. J., Apr 2005, In : Cell Metabolism. 1, 4, p. 231-244 14 p.

Research output: Contribution to journalArticle

225 Scopus citations

The capsaicin-sensetive afferent neuron in skeletal muscle is abnormal in heart failure

Smith, S. A., Williams, M. A., Mitchell, J. H., Mammen, P. P. A. & Garry, M. G., Apr 26 2005, In : Circulation. 111, 16, p. 2056-2065 10 p.

Research output: Contribution to journalArticle

61 Scopus citations
2003

Emerging roles for myoglobin in the heart

Garry, D. J., Kanatous, S. B. & Mammen, P. P. A., Apr 2003, In : Trends in Cardiovascular Medicine. 13, 3, p. 111-116 6 p.

Research output: Contribution to journalArticle

50 Scopus citations

Hypoxia-induced left ventricular dysfunction in myoglobin-deficient mice

Mammen, P. P. A., Kanatous, S. B., Yuhanna, I. S., Shaul, P. W., Garry, M. G., Balaban, R. S. & Garry, D. J., Nov 2003, In : American Journal of Physiology - Heart and Circulatory Physiology. 285, 5 54-5

Research output: Contribution to journalArticle

27 Scopus citations

Neuroprotection and the role of neuroglobin

Garry, D. J. & Mammen, P. P. A., Aug 2 2003, In : Lancet. 362, 9381, p. 342-343 2 p.

Research output: Contribution to journalArticle

40 Scopus citations

Role of the exercise pressor reflex in rats with dilated cardiomyopathy

Smith, S. A., Mammen, P. P. A., Mitchell, J. H. & Garry, M. G., Sep 2 2003, In : Circulation. 108, 9, p. 1126-1132 7 p.

Research output: Contribution to journalArticle

59 Scopus citations
2002

Neuroglobin, a novel member of the globin family, is expressed in focal regions of the brain

Mammen, P. P. A., Shelton, J. M., Goetsch, S. C., Williams, S. C., Richardson, J. A., Garry, M. G. & Garry, D. J., Dec 1 2002, In : Journal of Histochemistry and Cytochemistry. 50, 12, p. 1591-1598 8 p.

Research output: Contribution to journalArticle

120 Scopus citations
2001

Adaptive mechanisms that preserve cardiac function in mice without myoglobin

Meeson, A. P., Radford, N., Shelton, J. M., Mammen, P. P. A., DiMaio, J. M., Hutcheson, K., Kong, Y., Elterman, J., Williams, R. S. & Garry, D. J., Apr 13 2001, In : Circulation Research. 88, 7, p. 713-720 8 p.

Research output: Contribution to journalArticle

63 Scopus citations