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External positions

Children's Research Institute

Fingerprint Dive into the research topics where Ralph J DeBerardinis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 29 Similar Profiles
Neoplasms Medicine & Life Sciences
Metabolism Chemical Compounds
Glutamine Medicine & Life Sciences
Glycolysis Medicine & Life Sciences
Growth Medicine & Life Sciences
Glucose Medicine & Life Sciences
Tumors Chemical Compounds
Cells Chemical Compounds

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Research Output 1996 2019

AIF: an acquired metabolic liability in lung cancer

Faubert, B., DeBerardinis, R. J. & Minna, J. D., Jan 1 2019, In : Cell Research.

Research output: Contribution to journalArticle

Open Access
Lung Neoplasms

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, P. B., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access
Carbamyl Phosphate
Lung Neoplasms
DNA
pyrimidine
phosphorylethanolamine
4 Citations (Scopus)

Autophagy Regulation of Metabolism Is Required for CD8 + T Cell Anti-tumor Immunity

DeVorkin, L., Pavey, N., Carleton, G., Comber, A., Ho, C., Lim, J., McNamara, E., Huang, H., Kim, P., Zacharias, L. G., Mizushima, N., Saitoh, T., Akira, S., Beckham, W., Lorzadeh, A., Moksa, M., Cao, Q., Murthy, A., Hirst, M., DeBerardinis, R. J. & 1 others, Lum, J. J., Apr 9 2019, In : Cell Reports. 27, 2, p. 502-513.e5

Research output: Contribution to journalArticle

Open Access
T-cells
Autophagy
Metabolism
Tumors
Immunity
15 Citations (Scopus)

Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

Vriens, K., Christen, S., Parik, S., Broekaert, D., Yoshinaga, K., Talebi, A., Dehairs, J., Escalona-Noguero, C., Schmieder, R., Cornfield, T., Charlton, C., Romero-Pérez, L., Rossi, M., Rinaldi, G., Orth, M. F., Boon, R., Kerstens, A., Kwan, S. Y., Faubert, B., Méndez-Lucas, A. & 26 others, Kopitz, C. C., Chen, T., Fernandez-Garcia, J., Duarte, J. A. G., Schmitz, A. A., Steigemann, P., Najimi, M., Hägebarth, A., Van Ginderachter, J. A., Sokal, E., Gotoh, N., Wong, K. K., Verfaillie, C., Derua, R., Munck, S., Yuneva, M., Beretta, L., DeBerardinis, R. J., Swinnen, J. V., Hodson, L., Cassiman, D., Verslype, C., Christian, S., Grünewald, S., Grünewald, T. G. P. & Fendt, S. M., Feb 21 2019, In : Nature. 566, 7744, p. 403-406 4 p.

Research output: Contribution to journalLetter

Fatty Acids
Neoplasms
Stearoyl-CoA Desaturase
Palmitates
Lipid Metabolism
1 Citation (Scopus)

Functional Assessment of Lipoyltransferase-1 Deficiency in Cells, Mice, and Humans

Ni, M., Solmonson, A., Pan, C., Yang, C., Li, D., Notzon, A., Cai, L., Guevara, G., Zacharias, L. G., Faubert, B., Vu, H. S., Jiang, L., Ko, B., Morales, N. M., Pei, J., Dias do Vale, G., Rakheja, D., Grishin, N. V., McDonald, J. G., Gotway, G. K. & 3 others, McNutt, M. C., Pascual, J. M. & DeBerardinis, R. J., Apr 30 2019, In : Cell Reports. 27, 5, p. 1376-1386.e6

Research output: Contribution to journalArticle

Open Access
Functional assessment
Inborn Errors Metabolism
Metabolomics
Genomics
Metabolism