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External positions

Children's Research Institute

Fingerprint Dive into the research topics where Ralph J DeBerardinis is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 36 Similar Profiles
Neoplasms Medicine & Life Sciences
Metabolism Chemical Compounds
Glutamine Medicine & Life Sciences
Glucose Medicine & Life Sciences
Glycolysis Medicine & Life Sciences
Growth Medicine & Life Sciences
Tumors Chemical Compounds
Cells Chemical Compounds

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Research Output 1996 2019

Gluconeogenesis
Pyruvic Acid
Hepatocellular Carcinoma
Oxidoreductases
Pyruvate Carboxylase

AIF: an acquired metabolic liability in lung cancer

Faubert, B., DeBerardinis, R. J. & Minna, J. D., Jan 1 2019, In : Cell Research.

Research output: Contribution to journalArticle

Open Access
Lung Neoplasms
1 Citation (Scopus)

A novel mitochondrial inhibitor blocks MAPK pathway and overcomes MAPK inhibitor resistance in melanoma

Gopal, Y. N. V., Gammon, S., Prasad, R., Knighton, B., Pisaneschi, F., Roszik, J., Feng, N., Johnson, S., Pramanik, S., Sudderth, J., Sui, D., Hudgens, C., Fischer, G. M., Deng, W., Reuben, A., Peng, W., Wang, J., McQuade, J. L., Tetzlaff, M. T., Di Francesco, M. E. & 4 others, Marszalek, J., Piwnica-Worms, D., DeBerardinis, R. J. & Davies, M. A., Nov 1 2019, In : Clinical Cancer Research. 25, 21, p. 6429-6442 14 p.

Research output: Contribution to journalArticle

Oxidative Phosphorylation
Melanoma
AMP-Activated Protein Kinases
Glucose
Metabolomics

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, B. P. C., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access
Carbamyl Phosphate
Lung Neoplasms
DNA
pyrimidine
phosphorylethanolamine
7 Citations (Scopus)

Autophagy Regulation of Metabolism Is Required for CD8 + T Cell Anti-tumor Immunity

DeVorkin, L., Pavey, N., Carleton, G., Comber, A., Ho, C., Lim, J., McNamara, E., Huang, H., Kim, P., Zacharias, L. G., Mizushima, N., Saitoh, T., Akira, S., Beckham, W., Lorzadeh, A., Moksa, M., Cao, Q., Murthy, A., Hirst, M., DeBerardinis, R. J. & 1 others, Lum, J. J., Apr 9 2019, In : Cell Reports. 27, 2, p. 502-513.e5

Research output: Contribution to journalArticle

Open Access
T-cells
Autophagy
Metabolism
Tumors
Immunity