• 2791 Citations
  • 28 h-Index
19942018
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Research Output 1994 2018

  • 2791 Citations
  • 28 h-Index
  • 63 Article
  • 5 Conference contribution
  • 1 Comment/debate
4 Citations (Scopus)
ligaments
Ligaments
Tissue
shear
Decomposition

Viscoelastic properties of human aryepiglottic fold and ventricular fold tissues at phonatory frequencies

Kimura, M. & Chan, R. W., Jan 1 2018, (Accepted/In press) In : Laryngoscope.

Research output: Contribution to journalArticle

Vocal Cords
Mucous Membrane
Phonation
Laryngectomy
Elastic Modulus
2017
3 Citations (Scopus)
Statistical methods
Tissue
Animals
Rheometers
Elastic moduli
2014
5 Citations (Scopus)

Collagen microstructure in the vocal ligament: Initial results on the potential effects of smoking

Kelleher, J. E., Siegmund, T. & Chan, R. W., 2014, In : Laryngoscope. 124, 9

Research output: Contribution to journalArticle

Vocal Cords
Collagen
Smoking
Cohort Studies
Retrospective Studies

Comparison of two laryngeal tissue fiber constitutive models

Hunter, E. J., Palaparthi, A. K. R., Siegmund, T. & Chan, R. W., Feb 2014, In : Mechanics of Time-Dependent Materials. 18, 1, p. 179-196 18 p.

Research output: Contribution to journalArticle

Constitutive models
Tissue
Fibers
Shear viscosity
Parameterization
2 Citations (Scopus)

Strain modulations as a mechanism to reduce stress relaxation in laryngeal tissues

Hunter, E. J., Siegmund, T. & Chan, R. W., Mar 10 2014, In : PLoS One. 9, 3, e90762.

Research output: Contribution to journalArticle

stress relaxation
Vocal Cords
Stress relaxation
Modulation
Tissue
2013
16 Citations (Scopus)

Empirical measurements of biomechanical anisotropy of the human vocal fold lamina propria

Kelleher, J. E., Siegmund, T., Du, M., Naseri, E. & Chan, R. W., Jun 2013, In : Biomechanics and Modeling in Mechanobiology. 12, 3, p. 555-567 13 p.

Research output: Contribution to journalArticle

Lamina
Vocal Cords
Anisotropy
Indentation
Mucous Membrane
9 Citations (Scopus)

The anisotropic hyperelastic biomechanical response of the vocal ligament and implications for frequency regulation: A case study

Kelleher, J. E., Siegmund, T., Du, M., Naseri, E. & Chan, R. W., Mar 2013, In : Journal of the Acoustical Society of America. 133, 3, p. 1625-1636 12 p.

Research output: Contribution to journalArticle

frequency control
ligaments
elongation
shear
continuums
2012
4 Citations (Scopus)

Could spatial heterogeneity in human vocal fold elastic properties improve the quality of phonation?

Kelleher, J. E., Siegmund, T. & Chan, R. W., 2012, In : Annals of Biomedical Engineering. 40, 12, p. 2708-2718 11 p.

Research output: Contribution to journalArticle

Spatial distribution
Elastic moduli
Acoustics
Mucous Membrane
10 Citations (Scopus)

Modulating phonation through alteration of vocal fold medial surface contour

Mau, T., Muhlestein, J., Callahan, S. & Chan, R. W., Sep 2012, In : Laryngoscope. 122, 9, p. 2005-2014 10 p.

Research output: Contribution to journalArticle

Phonation
Vocal Cords
Pressure
Hyaluronic Acid
Durapatite
2011
29 Citations (Scopus)

Injection of human mesenchymal stem cells improves healing of vocal folds after scar excision - A xenograft analysis

Svensson, B., Nagubothu, S. R., Cedervall, J., Chan, R. W., Le Blanc, K., Kimura, M., Ährlund-Richter, L., Tolf, A. & Hertegård, S., Oct 2011, In : Laryngoscope. 121, 10, p. 2185-2190 6 p.

Research output: Contribution to journalArticle

Vocal Cords
Mesenchymal Stromal Cells
Heterografts
Cicatrix
Injections
9 Citations (Scopus)

Local vascularized flaps for augmentation of reinke's space

Dailey, S. H., Gunderson, M., Chan, R., Torrealba, J., Kimura, M. & Welham, N. V., Feb 2011, In : Laryngoscope. 121, SUPPL. 3

Research output: Contribution to journalArticle

Thyroid Gland
Larynx
Vocal Cords
Mucous Membrane
Deglutition
17 Citations (Scopus)

Optical measurements of vocal fold tensile properties: Implications for phonatory mechanics

Kelleher, J. E., Siegmund, T., Chan, R. W. & Henslee, E. A., Jun 3 2011, In : Journal of Biomechanics. 44, 9, p. 1729-1734 6 p.

Research output: Contribution to journalArticle

Vocal Cords
Mechanics
Tensile properties
Tissue
Cartilage
15 Citations (Scopus)

Phonation threshold pressure and flow in excised human larynges

Mau, T., Muhlestein, J., Callahan, S., Weinheimer, K. T. & Chan, R. W., Aug 2011, In : Laryngoscope. 121, 8, p. 1743-1751 9 p.

Research output: Contribution to journalArticle

Phonation
Larynx
Pressure
5 Citations (Scopus)

Rheometric properties of canine vocal fold tissues: Variation with anatomic location

Kimura, M., Mau, T. & Chan, R. W., Jun 2011, In : Auris Nasus Larynx. 38, 3, p. 367-372 6 p.

Research output: Contribution to journalArticle

Anatomic Variation
Vocal Cords
Canidae
Laryngeal Muscles
Vibration
13 Citations (Scopus)

Viscoelastic properties of fresh human lenses under 40 years of age: Implications for the aetiology of presbyopia

Schachar, R. A., Chan, R. W. & Fu, M., Jul 2011, In : British Journal of Ophthalmology. 95, 7, p. 1010-1013 4 p.

Research output: Contribution to journalArticle

Presbyopia
Lenses
Elastic Modulus
Cadaver
Viscosity
2010
32 Citations (Scopus)

A bovine acellular scaffold for vocal fold reconstruction in a rat model

Xu, C. C., Chan, R. W., Weinberger, D. G., Efune, G. & Pawlowski, K. S., Jan 2010, In : Journal of Biomedical Materials Research - Part A. 92, 1, p. 18-32 15 p.

Research output: Contribution to journalArticle

Scaffolds
Rats
Collagen
Glycosaminoglycans
Tissue Scaffolds

Acellular tissue engineering scaffolds for vocal fold regeneration

Chan, R. W., 2010, 2010 4th International Conference on Bioinformatics and Biomedical Engineering, iCBBE 2010. 5517382

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Tissue Scaffolds
Vocal Cords
Tissue Engineering
Scaffolds (biology)
Umbilical Veins
17 Citations (Scopus)

Arytenoid adduction for correcting vocal fold asymmetry: High-speed imaging

Kimura, M., Imagawa, H., Nito, T., Sakakibara, K. I., Chan, R. W. & Tayama, N., 2010, In : Annals of Otology, Rhinology and Laryngology. 119, 7, p. 439-446 8 p.

Research output: Contribution to journalArticle

Vocal Cords
Vibration
Paralysis
Phonation
Larynx
17 Citations (Scopus)

Collagen injection for correcting vocal fold asymmetry: High-speed imaging

Kimura, M., Nito, T., Imagawa, H., Sakakibara, K. I., Chan, R. W. & Tayama, N., Jun 2010, In : Annals of Otology, Rhinology and Laryngology. 119, 6, p. 359-368 10 p.

Research output: Contribution to journalArticle

Vocal Cords
Vibration
Collagen
Injections
Paralysis
21 Citations (Scopus)

Controlled release of hepatocyte growth factor from a bovine acellular scaffold for vocal fold reconstruction

Xu, C. C., Chan, R. W., Weinberger, D. G., Efune, G. & Pawlowski, K. S., Jun 15 2010, In : Journal of Biomedical Materials Research - Part A. 93, 4, p. 1335-1347 13 p.

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Scaffolds
Rats
Surgery
Hyaluronic acid
21 Citations (Scopus)

Spatially varying properties of the vocal ligament contribute to its eigenfrequency response

Kelleher, J. E., Zhang, K., Siegmund, T. & Chan, R. W., Nov 2010, In : Journal of the Mechanical Behavior of Biomedical Materials. 3, 8, p. 600-609 10 p.

Research output: Contribution to journalArticle

Ligaments
Anisotropy
Elastic moduli
Geometry
Shear deformation
1 Citation (Scopus)

The human umbilical vein as a biologic scaffold for vocal fold reconstruction

Chan, R. W., 2010, Proceedings of the 2010 IEEE 36th Annual Northeast Bioengineering Conference, NEBEC 2010. 5458281

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Scaffolds
Scaffolds (biology)
Fibroblasts
Tissue
Tissue engineering
32 Citations (Scopus)

Viscoelastic properties of phonosurgical biomaterials at phonatory frequencies

Kimura, M., Mau, T. & Chan, R. W., Apr 2010, In : Laryngoscope. 120, 4, p. 764-768 5 p.

Research output: Contribution to journalArticle

Vocal Cords
Biocompatible Materials
Mucous Membrane
Elastic Modulus
Hyaluronic Acid
2009
10 Citations (Scopus)

Biomechanics of fundamental frequency regulation: Constitutive modeling of the vocal fold lamina propria

Chan, R. W., Siegmund, T. & Zhang, K., 2009, In : Logopedics Phoniatrics Vocology. 34, 4, p. 181-189 9 p.

Research output: Contribution to journalArticle

Vocal Cords
Biomechanical Phenomena
Mucous Membrane
Laryngeal Muscles
Phonation

Controlled release of hepatocyte growth factor from a bovine acellular scaffoldfor vocal fold reconstruction

Xu, C. C., Chan, R. W., Weinberger, D. G., Efune, G. & Pawlowski, K. S., 2009, In : Laryngoscope. 119, SUPPL.3

Research output: Contribution to journalArticle

Hepatocyte Growth Factor
Vocal Cords
20 Citations (Scopus)

Modeling of the transient responses of the vocal fold lamina propria

Zhang, K., Siegmund, T. & Chan, R. W., Jan 2009, In : Journal of the Mechanical Behavior of Biomedical Materials. 2, 1, p. 93-104 12 p.

Research output: Contribution to journalArticle

Ligaments
Transient analysis
Stress relaxation
Creep
Tissue
12 Citations (Scopus)

Predictions of Fundamental Frequency Changes During Phonation Based on a Biomechanical Model of the Vocal Fold Lamina Propria

Zhang, K., Siegmund, T., Chan, R. W. & Fu, M., May 2009, In : Journal of Voice. 23, 3, p. 277-282 6 p.

Research output: Contribution to journalArticle

Phonation
Vocal Cords
Mucous Membrane
Structural Models
Vibration

Stereoscopic high-speed digital imaging of neoglottic vibration in esophageal speech

Kimura, M., Imagawa, H., Sakakibara, K. I., Nito, T., Tayama, N. & Chan, R. W., 2009, In : Laryngoscope. 119, SUPPL.3

Research output: Contribution to journalArticle

Esophageal Speech
Vibration
16 Citations (Scopus)

The human umbilical vein with wharton's jelly as an allogeneic, acellular construct for vocal fold restoration

Chan, R. W., Rodriguez, M. L. & McFetridge, P. S., Nov 1 2009, In : Tissue Engineering - Part A. 15, 11, p. 3537-3546 10 p.

Research output: Contribution to journalArticle

Wharton Jelly
Umbilical Veins
Vocal Cords
Fibroblasts
Restoration
2008
65 Citations (Scopus)
rheometers
shear
shear properties
audio frequencies
piezoelectric transducers
13 Citations (Scopus)

Collagen injection as a supplement to arytenoid adduction for vocal fold paralysis

Kimura, M., Nito, T., Imagawa, H., Tayama, N. & Chan, R. W., Jun 2008, In : Annals of Otology, Rhinology and Laryngology. 117, 6, p. 430-436 7 p.

Research output: Contribution to journalArticle

Vocal Cords
Paralysis
Collagen
Injections
Voice Quality
15 Citations (Scopus)

Pore architecture of a bovine acellular vocal fold scaffold

Xu, C. C. & Chan, R. W., Nov 1 2008, In : Tissue Engineering - Part A.. 14, 11, p. 1893-1903 11 p.

Research output: Contribution to journalArticle

Vocal Cords
Scaffolds
Porosity
Permeability
Pore size
2007
90 Citations (Scopus)

A biodegradable, acellular xenogeneic scaffold for regeneration of the vocal fold lamina propria

Xu, C. C., Chan, R. W. & Tirunagari, N., Mar 2007, In : Tissue Engineering. 13, 3, p. 551-566 16 p.

Research output: Contribution to journalArticle

Vocal Cords
Scaffolds
Regeneration
Mucous Membrane
Fibroblasts
21 Citations (Scopus)

A two-layer composite model of the vocal fold lamina propria for fundamental frequency regulation

Zhang, K., Siegmund, T. & Chan, R. W., 2007, In : Journal of the Acoustical Society of America. 122, 2, p. 1090-1101 12 p.

Research output: Contribution to journalArticle

frequency control
ligaments
composite materials
larynx
tensile deformation
73 Citations (Scopus)

Relative contributions of collagen and elastin to elasticity of the vocal fold under tension

Chan, R. W., Fu, M., Young, L. & Tirunagari, N., Aug 2007, In : Annals of Biomedical Engineering. 35, 8, p. 1471-1483 13 p.

Research output: Contribution to journalArticle

Elastin
Ligaments
Collagen
Elasticity
Tensile strain
14 Citations (Scopus)

Viscoelastic shear properties of the fresh porcine lens

Schachar, R. A., Chan, R. W. & Fu, M., Mar 2007, In : British Journal of Ophthalmology. 91, 3, p. 366-368 3 p.

Research output: Contribution to journalArticle

Lenses
Swine
Elastic Modulus
Viscosity
Cataract
2006
44 Citations (Scopus)

A constitutive model of the human vocal fold cover for fundamental frequency regulation

Zhang, K., Siegmund, T. & Chan, R. W., Feb 2006, In : Journal of the Acoustical Society of America. 119, 2, p. 1050-1062 13 p.

Research output: Contribution to journalArticle

frequency control
tensile deformation
epithelium
confidence
strings
89 Citations (Scopus)

Dependence of phonation threshold pressure on vocal tract acoustics and vocal fold tissue mechanics

Chan, R. W. & Titze, I. R., Apr 2006, In : Journal of the Acoustical Society of America. 119, 4, p. 2351-2362 12 p.

Research output: Contribution to journalArticle

reactance
thresholds
acoustics
energy transfer
shear properties
18 Citations (Scopus)

Elasticity of the human false vocal fold

Chan, R. W., Fu, M. & Tirunagari, N., May 2006, In : Annals of Otology, Rhinology and Laryngology. 115, 5, p. 370-381 12 p.

Research output: Contribution to journalArticle

Vocal Cords
Elastic Modulus
Elasticity
Phonation
Orosomucoid
2005

An expanded network model for the characterization of vocal fold deformation

Zhang, K., Siegmund, T. & Chan, R., 2005, Proceedings of the 2005 Summer Bioengineering Conference. Vol. 2005. p. 820-821 2 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2004
124 Citations (Scopus)

Characterization of chronic vocal fold scarringin a rabbit model

Rousseau, B., Hirano, S., Chan, R. W., Welham, N. V., Thibeault, S. L., Ford, C. N. & Bless, D. M., Mar 2004, In : Journal of Voice. 18, 1, p. 116-124 9 p.

Research output: Contribution to journalArticle

Vocal Cords
Rabbits
Mucous Membrane
Elastin
Collagen
39 Citations (Scopus)
viscoelasticity
shear properties
frequency ranges
shear
larynx
89 Citations (Scopus)

Prevention of Vocal Fold Scarring by Topical Injection of Hepatocyte Factor in A Rabbit Model

Hirano, S., Bless, D. M., Rousseau, B., Welham, N., Montequin, D., Chan, R. W. & Ford, C. N., Mar 2004, In : Laryngoscope. 114, 3, p. 548-556 9 p.

Research output: Contribution to journalArticle

Vocal Cords
Hepatocyte Growth Factor
Cicatrix
Hepatocytes
Rabbits

Structural constitutive characterization of the vocal fold: Modeling the fibrous and the interstitial matrix proteins

Chan, R. W., Siegmund, T. H., Zhang, K., Tirunagari, N. & Fu, M., 2004, Advances in Bioengineering, BED. American Society of Mechanical Engineers (ASME), p. 317-318 2 p. IMECE2004-61298

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Proteins
13 Citations (Scopus)

Vocal fold tissue failure: Preliminary data and constitutive modeling

Chan, R. W. & Siegmund, T., Aug 2004, In : Journal of Biomechanical Engineering. 126, 4, p. 466-474 9 p.

Research output: Contribution to journalArticle

Vocal Cords
Tissue
Extracellular Matrix
Phonation
Mucous Membrane
2003
17 Citations (Scopus)

An investigation of cricoarytenoid joint mechanics using simulated muscle forces

Berry, D. A., Montequin, D. W., Chan, R. W., Titze, I. R. & Hoffman, H. T., 2003, In : Journal of Voice. 17, 1, p. 47-62 16 p.

Research output: Contribution to journalArticle

Larynx
Mechanics
Arytenoid Cartilage
Joints
Voice Quality
152 Citations (Scopus)

Characterization of vocal fold scarring in a canine model

Rousseau, B., Hirano, S., Scheidt, T. D., Welham, N. V., Thibeault, S. L., Chan, R. W. & Bless, D. M., Apr 1 2003, In : Laryngoscope. 113, 4, p. 620-627 8 p.

Research output: Contribution to journalArticle

Vocal Cords
Elastin
Cicatrix
Canidae
Collagen
81 Citations (Scopus)

Effect of postmortem changes and freezing on the viscoelastic properties of vocal fold tissues

Chan, R. W. & Titze, I. R., 2003, In : Annals of Biomedical Engineering. 31, 4, p. 482-491 10 p.

Research output: Contribution to journalArticle

Freezing
Elasticity
Viscosity
Tissue
Cooling