Research Output per year
Fingerprint Dive into the research topics where Rolf A Brekken is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Vascular Endothelial Growth Factor A
Medicine & Life Sciences
Neoplasms
Medicine & Life Sciences
Pancreatic Neoplasms
Medicine & Life Sciences
Tumors
Chemical Compounds
Vascular Endothelial Growth Factor Receptor-2
Medicine & Life Sciences
Blood Vessels
Medicine & Life Sciences
Growth
Medicine & Life Sciences
Adenocarcinoma
Medicine & Life Sciences
Network
Recent external collaboration on country level. Dive into details by clicking on the dots.
Research Output 1998 2019
2-Amino-2,3-dihydro-1 H-indene-5-carboxamide-Based Discoidin Domain Receptor 1 (DDR1) Inhibitors: Design, Synthesis, and in Vivo Antipancreatic Cancer Efficacy
Zhu, D., Huang, H., Pinkas, D. M., Luo, J., Ganguly, D., Fox, A. E., Arner, E., Xiang, Q., Tu, Z. C., Bullock, A. N., Brekken, R. A., Ding, K. & Lu, X., Jan 1 2019, (Accepted/In press) In : Journal of Medicinal Chemistry.Research output: Contribution to journal › Article
Pancreatic Neoplasms
Neoplasms
Epithelial-Mesenchymal Transition
Inhibitory Concentration 50
Phosphotransferases
APR-246 alone and in combination with a phosphatidylserine-targeting antibody inhibits lung metastasis of human triple-negative breast cancer cells in nude mice
Liang, Y., Besch-Williford, C., Cook, M. T., Belenchia, A., Brekken, R. A. & Hyder, S. M., Jan 1 2019, In : Breast Cancer: Targets and Therapy. 11, p. 249-259 11 p.Research output: Contribution to journal › Article
Open Access
Triple Negative Breast Neoplasms
Phosphatidylserines
Nude Mice
Neoplasm Metastasis
Lung
Axl-mediated activation of TBK1 drives epithelial plasticity in pancreatic cancer
Cruz, V. H., Arner, E. N., Du, W., Bremauntz, A. E. & Brekken, R. A., Jan 1 2019, In : JCI Insight. 4, 9, e126117.Research output: Contribution to journal › Article
Pancreatic Neoplasms
Phosphotransferases
Adenocarcinoma
Epithelial-Mesenchymal Transition
Pharmacology
Cellular heterogeneity during mouse pancreatic ductal adenocarcinoma progression at single-cell resolution
Hosein, A. N., Huang, H., Wang, Z., Parmar, K., Du, W., Huang, J., Maitra, A., Olson, E. N., Verma, U. & Brekken, R. A., Jul 23 2019, In : JCI Insight. 4, 16, e129212.Research output: Contribution to journal › Article
Open Access
Adenocarcinoma
Fibroblasts
Neoplasms
Stromal Cells
Population
Cyclooxygenase-2 inhibition potentiates the efficacy of vascular endothelial growth factor blockade and promotes an immune stimulatory microenvironment in preclinical models of pancreatic cancer
Zhang, Y., Kirane, A., Huang, H., Sorrelle, N. B., Burrows, F. J., Dellinger, M. T. & Brekken, R. A., Feb 1 2019, In : Molecular Cancer Research. 17, 2, p. 348-355 8 p.Research output: Contribution to journal › Article
Cyclooxygenase 2
Pancreatic Neoplasms
Vascular Endothelial Growth Factor A
Adenocarcinoma
Therapeutics