• 5459 Citations
  • 35 h-Index
1984 …2018
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Fingerprint Dive into the research topics where Thomas M Wilkie is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 7 Similar Profiles
GTP-Binding Proteins Medicine & Life Sciences
RGS Proteins Medicine & Life Sciences
GTP-Binding Protein Regulators Medicine & Life Sciences
GTPase-Activating Proteins Medicine & Life Sciences
Protein Subunits Medicine & Life Sciences
Gq-G11 GTP-Binding Protein alpha Subunits Medicine & Life Sciences
G-Protein-Coupled Receptors Medicine & Life Sciences
Genes Medicine & Life Sciences

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Research Output 1984 2018

  • 5459 Citations
  • 35 h-Index
  • 62 Article
1 Citation (Scopus)

Malnutrition in Pancreatic Ductal Adenocarcinoma (PDA): Dietary Pancreatic Enzymes Improve Short-Term Health but Stimulate Tumor Growth

Zolghadri, Y., Pal Choudhuri, S., Ocal, O., Layeghi-Ghalehsoukhteh, S., Berhe, F., Hale, M. A. & Wilkie, T. M., Mar 1 2018, In : American Journal of Pathology. 188, 3, p. 616-626 11 p.

Research output: Contribution to journalArticle

Malnutrition
Adenocarcinoma
Health
Enzymes
Growth

The curious case of Gαs gain-of-function in neoplasia

Innamorati, G., Wilkie, T. M., Kantheti, H. S., Valenti, M. T., Dalle Carbonare, L., Giacomello, L., Parenti, M., Melisi, D. & Bassi, C., Mar 15 2018, In : BMC Cancer. 18, 1, 293.

Research output: Contribution to journalArticle

Mutation
Neoplasms
Polyostotic Fibrous Dysplasia
Phenotype
Poisons
17 Citations (Scopus)

The synthetic diazonamide DZ-2384 has distinct effects on microtubule curvature and dynamics without neurotoxicity

Wieczorek, M., Tcherkezian, J., Bernier, C., Prota, A. E., Chaaban, S., Rolland, Y., Godbout, C., Hancock, M. A., Arezzo, J. C., Ocal, O., Rocha, C., Olieric, N., Hall, A., Ding, H., Bramoullé, A., Annis, M. G., Zogopoulos, G., Harran, P. G., Wilkie, T. M., Brekken, R. A. & 5 others, Siegel, P. M., Steinmetz, M. O., Shore, G. C., Brouhard, G. J. & Roulston, A., Nov 16 2016, In : Science Translational Medicine. 8, 365

Research output: Contribution to journalArticle

Microtubules
Tubulin
Vinca
Vinca Alkaloids
Safety
7 Citations (Scopus)

A rapid in vivo screen for pancreatic ductal adenocarcinoma therapeutics

Ocal, O., Pashkov, V., Kollipara, R. K., Zolghadri, Y., Cruz, V. H., Hale, M. A., Heath, B. R., Artyukhin, A. B., Christie, A. L., Tsoulfas, P., Lorens, J. B., Swift, G. H., Brekken, R. A. & Wilkie, T. M., Oct 1 2015, In : DMM Disease Models and Mechanisms. 8, 10, p. 1201-1211 11 p.

Research output: Contribution to journalArticle

Tumors
Adenocarcinoma
Neoplasms
gemcitabine
G-Protein-Coupled Receptors
6 Citations (Scopus)

The G protein Gα11 is essential for hypertrophic signalling in diabetic myocardium

Reuter, H., Seuthe, K., Korkmaz, Y., Grönke, S., Hoyer, D. P., Rottlaender, D., Zobel, C., Addicks, K., Hoyer, J., Grimminger, P., Brabender, J., Wilkie, T. M. & Erdmann, E., Aug 20 2013, In : International Journal of Cardiology. 167, 4, p. 1476-1485 10 p.

Research output: Contribution to journalArticle

Gq-G11 GTP-Binding Protein alpha Subunits
Knockout Mice
Myocardium
Calcineurin
Cardiomegaly