• 4092 Citations
  • 34 h-Index
19992019

Research output per year

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Research Output

  • 4092 Citations
  • 34 h-Index
  • 93 Article
  • 7 Conference contribution
  • 2 Chapter
  • 1 Review article
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Article

[68Ga]-HP-DO3A-nitroimidazole: A promising agent for PET detection of tumor hypoxia

Wu, Y., Hao, G., Ramezani, S., Saha, D., Zhao, D., Sun, X. & Sherry, A. D., Nov 1 2015, In : Contrast Media and Molecular Imaging. 10, 6, p. 465-472 8 p.

Research output: Contribution to journalArticle

3 Scopus citations

64Cu-labeled folate-conjugated shell cross-linked nanoparticles for tumor imaging and radiotherapy: Synthesis, radiolabeling, and biologic evaluation

Rossin, R., Pan, D., Qi, K., Turner, J. L., Sun, X., Wooley, K. L. & Welch, M. J., 2005, In : Journal of Nuclear Medicine. 46, 7, p. 1210-1218 9 p.

Research output: Contribution to journalArticle

154 Scopus citations

A cell permeable peptide analog as a potential-specific PET imaging probe for prostate cancer detection

Hao, G., Zhou, J., Guo, Y., Long, M. A., Anthony, T., Stanfield, J., Hsieh, J. T. & Sun, X., Nov 2011, In : Amino Acids. 41, 5, p. 1093-1101 9 p.

Research output: Contribution to journalArticle

13 Scopus citations

A comparative study of trans- and cis-isomers of a bone-seeking agent, DO2A2P

Hao, G., Liu, W., Hassan, G., Öz, O. K., Kovacs, Z. & Sun, X., Feb 1 2015, In : Bioorganic and Medicinal Chemistry Letters. 25, 3, p. 571-574 4 p.

Research output: Contribution to journalArticle

2 Scopus citations

Advances in molecular imaging of pancreatic beta cells

Lin, M., Lubag, A., McGuire, M. J., Seliounine, S. Y., Tsyganov, E. N., Antich, P. P., Sherry, A. D., Brown, K. C. & Sun, X., 2008, In : Frontiers in Bioscience. 13, 12, p. 4558-4575 18 p.

Research output: Contribution to journalArticle

22 Scopus citations
6 Scopus citations

An Adipose Tissue Atlas: An Image-Guided Identification of Human-like BAT and Beige Depots in Rodents

Zhang, F., Hao, G., Shao, M., Nham, K., An, Y., Wang, Q., Zhu, Y., Kusminski, C., Hassan, G., Gupta, R. K., Zhai, Q., Sun, X., Scherer, P. E. & Oz, O. K., Jan 9 2018, In : Cell Metabolism. 27, 1, p. 252-262.e3

Research output: Contribution to journalArticle

27 Scopus citations

Analysis of oligo-arginine cell-permeable peptides uptake by prostate cells

Zhou, J., Liu, W., Pong, R. C., Hao, G., Sun, X. & Hsieh, J. T., Apr 2012, In : Amino Acids. 42, 4, p. 1253-1260 8 p.

Research output: Contribution to journalArticle

16 Scopus citations

An assessment of the effects of shell cross-linked nanoparticle size, core composition, and surface PEGylation on in vivo biodistribution

Sun, X., Rossin, R., Turner, J. L., Becker, M. L., Joralemon, M. J., Welch, M. J. & Wooley, K. L., Sep 1 2005, In : Biomacromolecules. 6, 5, p. 2541-2554 14 p.

Research output: Contribution to journalArticle

170 Scopus citations

An osteoclast-targeting agent for imaging and therapy of bone metastasis

Liu, W., Hajibeigi, A., Lin, M., Rostollan, C. L., Kovacs, Z., Öz, O. K. & Sun, X., Sep 1 2008, In : Bioorganic and Medicinal Chemistry Letters. 18, 17, p. 4789-4793 5 p.

Research output: Contribution to journalArticle

14 Scopus citations

Antitumor activity and molecular dynamics simulations of paclitaxel-laden triazine dendrimers

Lim, J., Lo, S. T., Hill, S., Pavan, G. M., Sun, X. & Simanek, E. E., Mar 5 2012, In : Molecular Pharmaceutics. 9, 3, p. 404-412 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

A silver-linked supramolecular cluster encapsulating a cesium cation

Sun, X., Johnson, D. W., Raymond, K. N. & Wong, E. H., Aug 13 2001, In : Inorganic Chemistry. 40, 17, p. 4504-4506 3 p.

Research output: Contribution to journalArticle

51 Scopus citations

A transistor-like pH nanoprobe for tumour detection and image-guided surgery

Zhao, T., Huang, G., Li, Y., Yang, S., Ramezani, S., Lin, Z., Wang, Y., Ma, X., Zeng, Z., Luo, M., De Boer, E., Xie, X. J., Thibodeaux, J., Brekken, R. A., Sun, X., Sumer, B. D. & Gao, J., Jan 10 2017, In : Nature Biomedical Engineering. 1, 1, 0006.

Research output: Contribution to journalArticle

50 Scopus citations

Attention-deficit/hyperactivity phenotype in mice lacking the cyclin-dependent kinase 5 cofactor p35

Drerup, J. M., Hayashi, K., Cui, H., Mettlach, G. L., Long, M. A., Marvin, M., Sun, X., Goldberg, M. S., Lutter, M. & Bibb, J. A., Dec 15 2010, In : Biological Psychiatry. 68, 12, p. 1163-1171 9 p.

Research output: Contribution to journalArticle

34 Scopus citations

Biological assessment of triazine dendrimer: Toxicological profiles, solution behavior, biodistribution, drug release and efficacy in a PEGylated, paclitaxel construct

Lo, S. T., Stern, S., Clogston, J. D., Zheng, J., Adiseshaiah, P. P., Dobrovolskaia, M., Lim, J., Patri, A. K., Sun, X. & Simanek, E. E., Aug 2 2010, In : Molecular Pharmaceutics. 7, 4, p. 993-1006 14 p.

Research output: Contribution to journalArticle

37 Scopus citations

Bombesin functionalized 64 Cu-copper sulfide nanoparticles for targeted imaging of orthotopic prostate cancer

Cai, H., Xie, F., Mulgaonkar, A., Chen, L., Sun, X., Hsieh, J. T., Peng, F., Tian, R., Li, L., Wu, C. & Ai, H., Jan 1 2018, In : Nanomedicine. 13, 14

Research output: Contribution to journalArticle

6 Scopus citations

Click-chemistry strategy for labeling antibodies with copper-64 via a cross-bridged tetraazamacrocyclic chelator scaffold

Kumar, A., Hao, G., Liu, L., Ramezani, S., Hsieh, J. T., Öz, O. K. & Sun, X., Apr 15 2015, In : Bioconjugate Chemistry. 26, 4, p. 782-789 8 p.

Research output: Contribution to journalArticle

15 Scopus citations

Comparative evaluation of two venous sampling techniques for the assessment of pancreatic insulin and zinc release upon glucose challenge

Pillai, A. K., Silvers, W., Christensen, P., Riegel, M., Adams-Huet, B., Lingvay, I., Sun, X. & Öz, O. K., 2015, In : Journal of Diabetes Research. 2015, 789359.

Research output: Contribution to journalArticle

Comparative in Vivo Stability of Copper-64-Labeled Cross-Bridged and Conventional Tetraazamacrocyclic Complexes

Boswell, C. A., Sun, X., Niu, W., Weisman, G. R., Wong, E. H., Rheingold, A. L. & Anderson, C. J., Mar 11 2004, In : Journal of Medicinal Chemistry. 47, 6, p. 1465-1474 10 p.

Research output: Contribution to journalArticle

369 Scopus citations

Control of cerebral ischemia with magnetic nanoparticles

Jia, J. M., Chowdary, P. D., Gao, X., Ci, B., Li, W., Mulgaonkar, A., Plautz, E. J., Hassan, G., Kumar, A., Stowe, A. M., Yang, S. H., Zhou, W., Sun, X., Cui, B. & Ge, W. P., Feb 1 2017, In : Nature Methods. 14, 2, p. 160-166 7 p.

Research output: Contribution to journalArticle

12 Scopus citations

C-terminal variable AGES domain of Thymosin β4: The molecule's primary contribution in support of post-ischemic cardiac function and repair

Hinkel, R., Ball, H. L., DiMaio, J. M., Shrivastava, S., Thatcher, J. E., Singh, A. N., Sun, X., Faskerti, G., Olson, E. N., Kupatt, C. & Bock-Marquette, I., Oct 1 2015, In : Journal of Molecular and Cellular Cardiology. 87, p. 113-125 13 p.

Research output: Contribution to journalArticle

12 Scopus citations

Cyclization of RGD peptide sequences via the macrocyclic chelator DOTA for integrin imaging

Hao, G., Sun, X., Do, Q. N., Ocampo-García, B., Vilchis-Juárez, A., Ferro-Flores, G. & De León-Rodríguez, L. M., Dec 14 2012, In : Dalton Transactions. 41, 46, p. 14051-14054 4 p.

Research output: Contribution to journalArticle

8 Scopus citations

Dendrimer nanoscaffolds for potential theranostics of prostate cancer with a focus on radiochemistry

Lo, S. T., Kumar, A., Hsieh, J. T. & Sun, X., 2013, In : Molecular Pharmaceutics. 10, 3, p. 793-812 20 p.

Research output: Contribution to journalArticle

62 Scopus citations

Dendrimers terminated with dichlorotriazine groups provide a route to compositional diversity

Patra, S., Kozura, B., Huang, A. Y. T., Enciso, A. E., Sun, X., Hsieh, J. T., Kao, C. L., Chen, H. T. & Simanek, E. E., Aug 2 2013, In : Organic Letters. 15, 15, p. 3808-3811 4 p.

Research output: Contribution to journalArticle

15 Scopus citations
4 Scopus citations
4 Scopus citations

Design, synthesis, characterization, and biological evaluation of triazine dendrimers bearing paclitaxel using ester and ester/disulfide linkages

Lim, J., Chouai, A., Lo, S. T., Liu, W., Sun, X. & Simanek, E. E., Nov 18 2009, In : Bioconjugate Chemistry. 20, 11, p. 2154-2161 8 p.

Research output: Contribution to journalArticle

66 Scopus citations

Design, synthesis and biological assessment of a triazine dendrimer with approximately 16 paclitaxel groups and 8 PEG groups

Lee, C., Lo, S. T., Lim, J., Da Costa, V. C. P., Ramezani, S., Öz, O. K., Pavan, G. M., Annunziata, O., Sun, X. & Simanek, E. E., Dec 2 2013, In : Molecular Pharmaceutics. 10, 12, p. 4452-4461 10 p.

Research output: Contribution to journalArticle

29 Scopus citations

Design of a Small-Molecule Drug Conjugate for Prostate Cancer Targeted Theranostics

Kumar, A., Mastren, T., Wang, B., Hsieh, J. T., Hao, G. & Sun, X., Jul 20 2016, In : Bioconjugate Chemistry. 27, 7, p. 1681-1689 9 p.

Research output: Contribution to journalArticle

16 Scopus citations

Differential expression of cell cycle regulators in CDK5-dependent medullary thyroid carcinoma tumorigenesis

Pozo, K., Hillmann, A., Augustyn, A., Plattner, F., Hai, T., Singh, T., Ramezani, S., Sun, X., Pfragner, R., Minna, J. D., Cote, G. J., Chen, H., Bibb, J. A. & Nwariaku, F. E., 2015, In : Oncotarget. 6, 14, p. 12080-12093 14 p.

Research output: Contribution to journalArticle

14 Scopus citations

Dimerization of a phage-display selected peptide for imaging of αvβ6- integrin: Two approaches to the multivalent effect

Singh, A. N., McGuire, M. J., Li, S., Hao, G., Kumar, A., Sun, X. & Brown, K. C., 2014, In : Theranostics. 4, 7, p. 745-760 16 p.

Research output: Contribution to journalArticle

18 Scopus citations

Effect of Trans-2,3-dimethoxycinnamoyl azide on enhancing antitumor activity of romidepsin on human bladder cancer

Fan, J., Stanfield, J., Guo, Y., Karam, J. A., Frenkel, E., Sun, X. & Hsieh, J. T., Feb 15 2008, In : Clinical Cancer Research. 14, 4, p. 1200-1207 8 p.

Research output: Contribution to journalArticle

9 Scopus citations

Enantiopure bifunctional chelators for copper radiopharmaceuticals - Does chirality matter in radiotracer design?

Singh, A. N., Dakanali, M., Hao, G., Ramezani, S., Kumar, A. & Sun, X., Jun 10 2014, In : European Journal of Medicinal Chemistry. 80, p. 308-315 8 p.

Research output: Contribution to journalArticle

7 Scopus citations

Exploiting incommensurate symmetry numbers: Rational design and assembly of M2M′3L6 supramolecular clusters with C3h symmetry

Sun, X., Johnson, D. W., Caulder, D. L., Powers, R. E., Raymond, K. N. & Wong, E. H., May 3 1999, In : Angewandte Chemie - International Edition. 38, 9, p. 1303-1307 5 p.

Research output: Contribution to journalArticle

78 Scopus citations

Folic acid-CdTe quantum dot conjugates and their applications for cancer cell targeting

Suriamoorthy, P., Zhang, X., Hao, G., Joly, A. G., Singh, S., Hossu, M., Sun, X. & Chen, W., Dec 2010, In : Cancer Nanotechnology. 1, 1-6, p. 19-28 10 p.

Research output: Contribution to journalArticle

38 Scopus citations

Glucose metabolism via the pentose phosphate pathway, glycolysis and Krebs cycle in an orthotopic mouse model of human brain tumors

Marin-Valencia, I., Cho, S. K., Rakheja, D., Hatanpaa, K. J., Kapur, P., Mashimo, T., Jindal, A., Vemireddy, V., Good, L. B., Raisanen, J. M., Sun, X., Mickey, B. E., Choi, C., Takahashi, M., Togao, O., Pascual, J. M., DeBerardinis, R. J., Maher, E. A., Malloy, C. R. & Bachoo, R., Oct 2012, In : NMR in Biomedicine. 25, 10, p. 1177-1186 10 p.

Research output: Contribution to journalArticle

43 Scopus citations

Glutathione-coated luminescent gold nanoparticles: A surface ligand for minimizing serum protein adsorption

Vinluan, R. D., Liu, J., Zhou, C., Yu, M., Yang, S., Kumar, A., Sun, S., Dean, A., Sun, X. & Zheng, J., Aug 13 2014, In : ACS Applied Materials and Interfaces. 6, 15, p. 11829-11833 5 p.

Research output: Contribution to journalArticle

28 Scopus citations

Gold nanotags for combined multi-colored Raman spectroscopy and x-ray computed tomography

Xiao, M., Nyagilo, J., Arora, V., Kulkarni, P., Xu, D., Sun, X. & Davé, D. P., 2010, In : Nanotechnology. 21, 3, 035101.

Research output: Contribution to journalArticle

51 Scopus citations

Highly specific PET imaging of prostate tumors in mice with an iodine-124-labeled antibody fragment that targets phosphatidylserine

Stafford, J. H., Hao, G., Best, A. M., Sun, X. & Thorpe, P. E., Dec 19 2013, In : PLoS One. 8, 12, e84864.

Research output: Contribution to journalArticle

14 Scopus citations

Hollow gold nanoparticles as biocompatible radiosensitizer: An in vitro proof of concept study

Huang, C., Kearney, V., Moeendarbari, S., Jiang, R., Christensen, P., Tekade, R., Sun, X., Mao, W. & Hao, Y., 2015, In : Journal of Nano Research. 32, p. 106-112 7 p.

Research output: Contribution to journalArticle

14 Scopus citations

Hollow gold nanoparticles as efficient in vivo radiosensitizing agents for radiation therapy of breast cancer

Mulgaonkar, A., Moeendarbari, S., Silvers, W., Hassan, G., Sun, X., Hao, Y. & Mao, W., May 1 2017, In : Journal of Biomedical Nanotechnology. 13, 5, p. 566-574 9 p.

Research output: Contribution to journalArticle

12 Scopus citations

Imaging copper metabolism imbalance in Atp7b-/-knockout mouse model of Wilson's disease with PET-CT and orally administered 64CuCl2

Peng, F., Lutsenko, S., Sun, X. & Muzik, O., Oct 2012, In : Molecular Imaging and Biology. 14, 5, p. 600-607 8 p.

Research output: Contribution to journalArticle

21 Scopus citations

Imparting multivalency to a bifunctional chelator: A scaffold design for targeted PET imaging probes

Liu, W., Hao, G., Long, M. A., Anthony, T., Hsieh, J. T. & Sun, X., Sep 21 2009, In : Angewandte Chemie - International Edition. 48, 40, p. 7346-7349 4 p.

Research output: Contribution to journalArticle

58 Scopus citations

Interactions of Renal-Clearable Gold Nanoparticles with Tumor Microenvironments: Vasculature and Acidity Effects

Yu, M., Zhou, C., Liu, L., Zhang, S., Sun, S., Hankins, J. D., Sun, X. & Zheng, J., Apr 3 2017, In : Angewandte Chemie - International Edition. 56, 15, p. 4314-4319 6 p.

Research output: Contribution to journalArticle

22 Scopus citations

In vivo behavior of copper-64-labeled methanephosphonate tetraaza macrocyclic ligands

Sun, X., Wuest, M., Kovacs, Z., Sherry, A. D., Motekaitis, R., Wang, Z., Martell, A. E., Welch, M. J. & Anderson, C. J., Jan 1 2003, In : Journal of Biological Inorganic Chemistry. 8, 1-2, p. 217-225 9 p.

Research output: Contribution to journalArticle

65 Scopus citations

In vivo evaluation of copper-64-labeled monooxo-tetraazamacrocyclic ligands

Sun, X., Kim, J., Martell, A. E., Welch, M. J. & Anderson, C. J., Nov 2004, In : Nuclear Medicine and Biology. 31, 8, p. 1051-1059 9 p.

Research output: Contribution to journalArticle

21 Scopus citations

In vivo evaluation of medical device-associated inflammation using a macrophage-specific positron emission tomography (PET) imaging probe

Zhou, J., Hao, G., Weng, H., Tsai, Y. T., Baker, D. W., Sun, X. & Tang, L., Apr 1 2013, In : Bioorganic and Medicinal Chemistry Letters. 23, 7, p. 2044-2047 4 p.

Research output: Contribution to journalArticle

12 Scopus citations

Labeling of adenovirus particles with PARACEST agents

Vasalatiy, O., Gerard, R. D., Zhao, P., Sun, X. & Sherry, A. D., Mar 2008, In : Bioconjugate Chemistry. 19, 3, p. 598-606 9 p.

Research output: Contribution to journalArticle

40 Scopus citations

Lin28b is sufficient to drive liver cancer and necessary for its maintenance in murine models

Nguyen, L. H., Robinton, D. A., Seligson, M. T., Wu, L., Li, L., Rakheja, D., Comerford, S. A., Ramezani, S., Sun, X., Parikh, M. S., Yang, E. H., Powers, J. T., Shinoda, G., Shah, S. P., Hammer, R. E., Daley, G. Q. & Zhu, H., Aug 11 2014, In : Cancer Cell. 26, 2, p. 248-261 14 p.

Research output: Contribution to journalArticle

93 Scopus citations

Luminescent gold nanoparticles with efficient renal clearance

Zhou, C., Long, M., Qin, Y., Sun, X. & Zheng, J., Mar 28 2011, In : Angewandte Chemie - International Edition. 50, 14, p. 3168-3172 5 p.

Research output: Contribution to journalArticle

255 Scopus citations