• 2547 Citations
  • 25 h-Index
20052019
If you made any changes in Pure, your changes will be visible here soon.

Personal profile

External positions

Children's Research Institute

Fingerprint Dive into the research topics where Zeping Hu is active. These topic labels come from the works of this person. Together they form a unique fingerprint.

  • 2 Similar Profiles
irinotecan Medicine & Life Sciences
Pharmacokinetics Chemical Compounds
Metabolomics Medicine & Life Sciences
Neoplasms Medicine & Life Sciences
Hypericum Medicine & Life Sciences
Rats Chemical Compounds
Thalidomide Medicine & Life Sciences
High performance liquid chromatography Chemical Compounds

Network Recent external collaboration on country level. Dive into details by clicking on the dots.

Research Output 2005 2019

  • 2547 Citations
  • 25 h-Index
  • 49 Article
  • 1 Comment/debate

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359)

Kim, J., Hu, Z., Cai, L., Li, K., Choi, E., Faubert, B., Bezwada, D., Rodriguez-Canales, J., Villalobos, P., Lin, Y. F., Ni, M., Huffman, K. E., Girard, L., Byers, L. A., Unsal-Kacmaz, K., Peña, C. G., Heymach, J. V., Wauters, E., Vansteenkiste, J., Castrillon, D. H. & 6 others, Chen, P. B., Wistuba, I., Lambrechts, D., Xu, J., Minna, J. D. & DeBerardinis, R. J., May 16 2019, In : Nature. 569, 7756, p. E4

Research output: Contribution to journalComment/debate

Open Access
Carbamyl Phosphate
Lung Neoplasms
DNA
pyrimidine
phosphorylethanolamine
1 Citation (Scopus)

Emerging Applications of Metabolomics in Clinical Pharmacology

Pang, H., Jia, W. & Hu, Z., Jan 1 2019, In : Clinical pharmacology and therapeutics.

Research output: Contribution to journalArticle

Metabolomics
Clinical Pharmacology
Pharmaceutical Preparations
Technology
Metabolic Networks and Pathways

MYC-driven small-cell lung cancer is metabolically distinct and vulnerable to arginine depletion

Chalishazar, M. D., Wait, S. J., Huang, F., Ireland, A. S., Mukhopadhyay, A., Lee, Y., Schuman, S. S., Guthrie, M. R., Berrett, K. C., Vahrenkamp, J. M., Hu, Z., Kudla, M., Modzelewska, K., Wang, G., Ingolia, N. T., Gertz, J., Lum, D. H., Cosulich, S. C., Bomalaski, J. S., DeBerardinis, R. J. & 1 others, Oliver, T. G., Aug 15 2019, In : Clinical Cancer Research. 25, 16, p. 5107-5121 15 p.

Research output: Contribution to journalArticle

Open Access
Small Cell Lung Carcinoma
Arginine
Heterografts
Cell Line
Neoplasms
2 Citations (Scopus)

Targeting the Oncogene KRAS Mutant Pancreatic Cancer by Synergistic Blocking of Lysosomal Acidification and Rapid Drug Release

Kong, C., Li, Y., Liu, Z., Ye, J., Wang, Z., Zhang, L., Kong, W., Liu, H., Liu, C., Pang, H., Hu, Z., Gao, J. & Qian, F., Jan 1 2019, In : ACS Nano.

Research output: Contribution to journalArticle

oncogenes
Acidification
Micelles
drugs
cancer
2 Citations (Scopus)

Arginine deficiency is involved in thrombocytopenia and immunosuppression in severe fever with thrombocytopenia syndrome

Li, X. K., Lu, Q. B., Chen, W. W., Xu, W., Liu, R., Zhang, S. F., Du, J., Li, H., Yao, K., Zhai, D., Zhang, P. H., Xing, B., Cui, N., Yang, Z. D., Yuan, C., Zhang, X. A., Xu, Z., Cao, W. C., Hu, Z. & Liu, W., Sep 19 2018, In : Science Translational Medicine. 10, 459, eaat4162.

Research output: Contribution to journalArticle

Thrombocytopenia
Immunosuppression
Arginine
Fever
Arginase