A clinical test useful for predicting the development of acute hypertension in pregnancy

N. F. Gant, S. Chand, R. J. Worley, P. J. Whalley, U. D. Crosby, P. C. MacDonald

Research output: Contribution to journalArticle

177 Citations (Scopus)

Abstract

93% of nulliparous, normotensive young women who subsequently developed pregnancy induced hypertension demonstrated an increase in diastolic blood pressure of at least 20 mm Hg when turned from the lateral recumbent to the supine position between the 28th and 32nd wks of gestation. Conversely, 91% of women who did not demonstrate such a rise in diastolic blood pressure when turned to the supine position did not become hypertensive during that pregnancy. Additionally, very close correlations were demonstrated between a positive supine pressor response and increased sensitivity to intravenously infused angiotensin II, and between a negative supine pressor response and increased resistance to angiotensin II.

Original languageEnglish (US)
Pages (from-to)1-7
Number of pages7
JournalAmerican Journal of Obstetrics and Gynecology
Volume120
Issue number1
StatePublished - 1974

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Blood Pressure
Hypertension
Pregnancy
Supine Position
Angiotensin II
Pregnancy Induced Hypertension

ASJC Scopus subject areas

  • Medicine(all)
  • Obstetrics and Gynecology

Cite this

A clinical test useful for predicting the development of acute hypertension in pregnancy. / Gant, N. F.; Chand, S.; Worley, R. J.; Whalley, P. J.; Crosby, U. D.; MacDonald, P. C.

In: American Journal of Obstetrics and Gynecology, Vol. 120, No. 1, 1974, p. 1-7.

Research output: Contribution to journalArticle

Gant, N. F. ; Chand, S. ; Worley, R. J. ; Whalley, P. J. ; Crosby, U. D. ; MacDonald, P. C. / A clinical test useful for predicting the development of acute hypertension in pregnancy. In: American Journal of Obstetrics and Gynecology. 1974 ; Vol. 120, No. 1. pp. 1-7.
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