A concise synthesis of (R)-hydroxy-E,Z-diene fatty acids: preparation of 12(R)-hete, tetranor-12(R)-hete, and 13(R)-hode

Sun Lumin, J R Falck, Michal L. Schwartzman

Research output: Contribution to journalArticle

12 Scopus citations

Abstract

Chiral E-enals derived from functionalized 2-deoxy-D-ribofuranoses by ylide-induced β-elimination were exploited for the synthesis of fatty acid metabolites containing the (R)-hydroxy-E,Z-diene subunit.

Original languageEnglish (US)
Pages (from-to)2315-2318
Number of pages4
JournalTetrahedron Letters
Volume32
Issue number21
DOIs
StatePublished - May 20 1991

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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