A convenient synthesis of unsymmetric polyfluoroethers

J. R. Falck, Jurong Yu, Hyun Sung Cho

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Condensation of alcohols with commercial polyfluorinated primary, secondary, and tertiary alcohols under modified Mitsunobu conditions affords unsymmetric polyfluoroethers in moderate to excellent yields.

Original languageEnglish (US)
Pages (from-to)5997-6000
Number of pages4
JournalTetrahedron Letters
Issue number33
StatePublished - Aug 15 1994


  • 1
  • 1′-(azodicarbonyl)dipiperidine
  • Mitsunobu
  • condensation
  • etherification
  • fluoroalcohol
  • tributylphosphine

ASJC Scopus subject areas

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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