A method is described for the removal of specific antibody from immunized animals. Rabbits were passively immunized with antibody to BSA and bacteriophage Ï†X. Their blood was exposed to bromoacetyl cellulose-BSA thru an extracorporeal circulation or the immunoadsorbent was mixed with large aliquots of their serum in vitro before returning the serum to them. Both of these methods resulted in a 32-84% reduction of circulating anti-BSA with little or no effect on anti-Ï†X.
|Original language||English (US)|
|Number of pages||4|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Sep 1969|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)