A Method of Removal of Specific Antibody from Immunized Rabbits

M. W. Graf, J. W. Uhr

Research output: Contribution to journalArticle

Abstract

A method is described for the removal of specific antibody from immunized animals. Rabbits were passively immunized with antibody to BSA and bacteriophage φX. Their blood was exposed to bromoacetyl cellulose-BSA thru an extracorporeal circulation or the immunoadsorbent was mixed with large aliquots of their serum in vitro before returning the serum to them. Both of these methods resulted in a 32-84% reduction of circulating anti-BSA with little or no effect on anti-φX.

Original languageEnglish (US)
Pages (from-to)1231-1234
Number of pages4
JournalProceedings of the Society for Experimental Biology and Medicine
Volume131
Issue number4
DOIs
StatePublished - Sep 1969

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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