A multiple echo pulse sequence for diffusion tensor imaging and its application in excised rat spinal cords

Vikas Gulani, Gary A. Iwamoto, Hong Jiang, Joshua S. Shimony, Andrew G. Webb, Paul C. Lauterbur

Research output: Contribution to journalArticle

54 Scopus citations

Abstract

A new imaging sequence for rapid determination of the apparent self- diffusion tensor of water was developed and tested on fixed excised rat spinal cords. To reduce the time required to determine the tensor, the sequence utilized a new single-shot approach with multiple spin echoes. An assumption of cylindrical symmetry in the sample was made, thus requiring the measurement of only four of the six unique elements of the tensor. This assumption was found experimentally to be valid, and the results obtained using the new sequence were found to be quantitatively the same as results obtained using a standard spin-echo sequence.

Original languageEnglish (US)
Pages (from-to)868-873
Number of pages6
JournalMagnetic resonance in medicine
Volume38
Issue number6
DOIs
StatePublished - Dec 1997

Keywords

  • Diffusion MRI
  • Diffusion tensor
  • Multiple echoes
  • Spinal cord

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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