### Abstract

Time-resolved imaging becomes popular in radiotherapy in that it significantly reduces blurring artifacts in volumetric images reconstructed from a set of 2D X-ray projection data. We aim at developing a neural network (NN) based machine learning algorithm that allows for reconstructing an instantaneous image from a single projection. In our approach, each volumetric image is represented as a deformation of a chosen reference image, in which the deformation is modeled as a linear combination of a few basis functions through principal component analysis (PCA). Based on this PCA deformation model, we train an ensemble of neural networks to find a mapping from a projection image to PCA coefficients. For image reconstruction, we apply the learned mapping on an instantaneous projection image to obtain the PCA coefficients, thus getting a deformation. Then, a volumetric image can be reconstructed by applying the deformation on the reference image. Experimentally, we show promising results on a set of simulated data.

Original language | English (US) |
---|---|

Title of host publication | Medical Image Understanding and Analysis - 23rd Conference, MIUA 2019, Proceedings |

Editors | Yalin Zheng, Bryan M. Williams, Ke Chen |

Publisher | Springer |

Pages | 208-219 |

Number of pages | 12 |

ISBN (Print) | 9783030393427 |

DOIs | |

State | Published - Jan 1 2020 |

Event | 23rd Conference on Medical Image Understanding and Analysis, MIUA 2019 - Liverpool, United Kingdom Duration: Jul 24 2019 → Jul 26 2019 |

### Publication series

Name | Communications in Computer and Information Science |
---|---|

Volume | 1065 CCIS |

ISSN (Print) | 1865-0929 |

ISSN (Electronic) | 1865-0937 |

### Conference

Conference | 23rd Conference on Medical Image Understanding and Analysis, MIUA 2019 |
---|---|

Country | United Kingdom |

City | Liverpool |

Period | 7/24/19 → 7/26/19 |

### Keywords

- Neural network
- Principal component analysis
- Time-resolved volumetric imaging
- X-ray projection

### ASJC Scopus subject areas

- Computer Science(all)
- Mathematics(all)

## Fingerprint Dive into the research topics of 'A Neural Network Approach for Image Reconstruction from a Single X-Ray Projection'. Together they form a unique fingerprint.

## Cite this

*Medical Image Understanding and Analysis - 23rd Conference, MIUA 2019, Proceedings*(pp. 208-219). (Communications in Computer and Information Science; Vol. 1065 CCIS). Springer. https://doi.org/10.1007/978-3-030-39343-4_18