A Review of Current Keloid Management: Mainstay Monotherapies and Emerging Approaches

Emily E. Limmer, Donald A. Glass

Research output: Contribution to journalReview article

Abstract

Commonly affecting those with skin of color, keloids are an aberrant wound response that leads to wound tissue expanding above and beyond the original cutaneous injury. Keloids are notoriously and particularly difficult to treat because of their tendency to recur after excision. The current standard of care is intralesional steroid (triamcinolone acetonide). However, because no therapy has yet proven to be fully curative, keloid treatments have expanded to include a number of options, from injections to multimodal approaches. This review details current treatment of keloids with injections (bleomycin, verapamil, hyaluronic acid and hyaluronidase, botulinum toxin, and collagenase), cryotherapy, laser, radiofrequency ablation, radiation, extracorporeal shockwave therapy, pentoxifylline, and dupilumab.

Original languageEnglish (US)
Pages (from-to)931-948
Number of pages18
JournalDermatology and Therapy
Volume10
Issue number5
DOIs
StateAccepted/In press - 2020

Keywords

  • CO laser
  • Cryotherapy
  • Intralesional injection
  • Keloid
  • Multimodal approach
  • Pulse dye laser
  • Radiation
  • Radiofrequency ablation
  • Wound healing

ASJC Scopus subject areas

  • Dermatology

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