TY - JOUR
T1 - A strategy for founding a global lymphocyte proteinpaedia and gene catalogue
AU - Lefkovits, Ivan
AU - Kettman, John R.
AU - Coleclough, Christopher
PY - 1990
Y1 - 1990
N2 - In this article, Ivan Lefkovits, John Kettman and Christopher Coleclough describe a strategy for a comprehensive analysis of the genes active in lymphocytes. It allows direct access to the coding sequence of any gene, provided that the two-dimensional gel spot coordinate position is known. The authors have constructed representative lymphocyte cDNA libraries and partitioned them into many sectors, each containing a unique set of cDNA clones. Data from the analysis of natural lymphocyte protein is compiled into a 'proteinpaedia', which is matched to a gene catalogue comprising the partitioned recombinant phage collection.
AB - In this article, Ivan Lefkovits, John Kettman and Christopher Coleclough describe a strategy for a comprehensive analysis of the genes active in lymphocytes. It allows direct access to the coding sequence of any gene, provided that the two-dimensional gel spot coordinate position is known. The authors have constructed representative lymphocyte cDNA libraries and partitioned them into many sectors, each containing a unique set of cDNA clones. Data from the analysis of natural lymphocyte protein is compiled into a 'proteinpaedia', which is matched to a gene catalogue comprising the partitioned recombinant phage collection.
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M3 - Article
SN - 1471-4906
VL - 11
SP - 157
EP - 162
JO - Trends in Immunology
JF - Trends in Immunology
IS - C
ER -