Acanthamoeba keratitis associated with contact lenses: Six consecutive cases of successful management

M. B. Moore, James P McCulley

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

We examined and treated six patients with acanthamoeba keratitis associated with contact lens wear from 1981 to 1988. Five patients were treated with topical neomycin-polymyxin B-gramicidin (Neosporin) and propamidine isethionate (Brolene) drops. The patients were followed up for an average of 32 months (range 16-75 months). Two patients underwent penetrating keratoplasty at 22 and 26 months after the onset of symptoms and have maintained clear grafts with no evidence of recurrence. In four patients corneal infiltrates cleared on topical medication. All six patients have 6/6 best corrected vision. Early diagnosis and medical treatment alone can result in resolution of corneal infiltrates due to acanthamoebae. With this initial therapy we have had no treatment failures.

Original languageEnglish (US)
Pages (from-to)271-275
Number of pages5
JournalBritish Journal of Ophthalmology
Volume73
Issue number4
StatePublished - 1989

Fingerprint

Acanthamoeba Keratitis
Contact Lenses
Case Management
Framycetin
Acanthamoeba
Gramicidin
Polymyxin B
Penetrating Keratoplasty
Treatment Failure
Early Diagnosis
Transplants
Recurrence
Therapeutics

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Acanthamoeba keratitis associated with contact lenses : Six consecutive cases of successful management. / Moore, M. B.; McCulley, James P.

In: British Journal of Ophthalmology, Vol. 73, No. 4, 1989, p. 271-275.

Research output: Contribution to journalArticle

@article{5ca13f88e19f48a095aae7de3cd73bc4,
title = "Acanthamoeba keratitis associated with contact lenses: Six consecutive cases of successful management",
abstract = "We examined and treated six patients with acanthamoeba keratitis associated with contact lens wear from 1981 to 1988. Five patients were treated with topical neomycin-polymyxin B-gramicidin (Neosporin) and propamidine isethionate (Brolene) drops. The patients were followed up for an average of 32 months (range 16-75 months). Two patients underwent penetrating keratoplasty at 22 and 26 months after the onset of symptoms and have maintained clear grafts with no evidence of recurrence. In four patients corneal infiltrates cleared on topical medication. All six patients have 6/6 best corrected vision. Early diagnosis and medical treatment alone can result in resolution of corneal infiltrates due to acanthamoebae. With this initial therapy we have had no treatment failures.",
author = "Moore, {M. B.} and McCulley, {James P}",
year = "1989",
language = "English (US)",
volume = "73",
pages = "271--275",
journal = "British Journal of Ophthalmology",
issn = "0007-1161",
publisher = "BMJ Publishing Group",
number = "4",

}

TY - JOUR

T1 - Acanthamoeba keratitis associated with contact lenses

T2 - Six consecutive cases of successful management

AU - Moore, M. B.

AU - McCulley, James P

PY - 1989

Y1 - 1989

N2 - We examined and treated six patients with acanthamoeba keratitis associated with contact lens wear from 1981 to 1988. Five patients were treated with topical neomycin-polymyxin B-gramicidin (Neosporin) and propamidine isethionate (Brolene) drops. The patients were followed up for an average of 32 months (range 16-75 months). Two patients underwent penetrating keratoplasty at 22 and 26 months after the onset of symptoms and have maintained clear grafts with no evidence of recurrence. In four patients corneal infiltrates cleared on topical medication. All six patients have 6/6 best corrected vision. Early diagnosis and medical treatment alone can result in resolution of corneal infiltrates due to acanthamoebae. With this initial therapy we have had no treatment failures.

AB - We examined and treated six patients with acanthamoeba keratitis associated with contact lens wear from 1981 to 1988. Five patients were treated with topical neomycin-polymyxin B-gramicidin (Neosporin) and propamidine isethionate (Brolene) drops. The patients were followed up for an average of 32 months (range 16-75 months). Two patients underwent penetrating keratoplasty at 22 and 26 months after the onset of symptoms and have maintained clear grafts with no evidence of recurrence. In four patients corneal infiltrates cleared on topical medication. All six patients have 6/6 best corrected vision. Early diagnosis and medical treatment alone can result in resolution of corneal infiltrates due to acanthamoebae. With this initial therapy we have had no treatment failures.

UR - http://www.scopus.com/inward/record.url?scp=0024564378&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0024564378&partnerID=8YFLogxK

M3 - Article

C2 - 2540794

AN - SCOPUS:0024564378

VL - 73

SP - 271

EP - 275

JO - British Journal of Ophthalmology

JF - British Journal of Ophthalmology

SN - 0007-1161

IS - 4

ER -