Acetaminophen hepatotoxicity in the alcoholic

F. T. Wootton, W. M. Lee

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

In a retrospective review from 1987 to 1989, we identified seven alcoholics who had severe acute hepatocellular injury soon after using acetaminophen for therapeutic purposes and who had no suicidal intent. All had markedly elevated serum transaminase values (aspartate aminotransferase > 4000 U/L) and prolonged prothrombin times. Three died. Use of acetaminophen by the alcoholic patient is potentially lethal.

Original languageEnglish (US)
Pages (from-to)1047-1049
Number of pages3
JournalSouthern Medical Journal
Volume83
Issue number9
StatePublished - 1990

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Alcoholics
Acetaminophen
Prothrombin Time
Aspartate Aminotransferases
Transaminases
Wounds and Injuries
Serum
Therapeutics

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Acetaminophen hepatotoxicity in the alcoholic. / Wootton, F. T.; Lee, W. M.

In: Southern Medical Journal, Vol. 83, No. 9, 1990, p. 1047-1049.

Research output: Contribution to journalArticle

Wootton, FT & Lee, WM 1990, 'Acetaminophen hepatotoxicity in the alcoholic', Southern Medical Journal, vol. 83, no. 9, pp. 1047-1049.
Wootton, F. T. ; Lee, W. M. / Acetaminophen hepatotoxicity in the alcoholic. In: Southern Medical Journal. 1990 ; Vol. 83, No. 9. pp. 1047-1049.
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