Acquired cutis laxa associated with heavy chain deposition disease

Cynthia R. Harrington; Tracy C. Beswick; Joseph S. Susa; Amit G. Pandya

doi:10.1016/j.jaad.2008.05.007

Acquired cutis laxa associated with heavy chain deposition disease

Cynthia R. Harrington, Tracy C. Beswick, Joseph S. Susa, Amit G. Pandya

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22 Scopus citations

Abstract

Acquired cutis laxa (generalized acquired elastolysis) is a condition of unknown etiology characterized by a degeneration of elastic fibers in the skin, resulting in laxity with reduced elastic recoil. We describe a patient with acquired cutis laxa associated with an underlying heavy chain deposition disease. Direct immunofluorescence testing of lesional skin demonstrated immunoglobulin G deposition on elastic fibers, suggesting that in some cases, cutis laxa may have an immune-mediated etiopathogenesis.

Original language	English (US)
Pages (from-to)	S99-S101
Journal	Journal of the American Academy of Dermatology
Volume	59
Issue number	5 SUPPL.
DOIs	https://doi.org/10.1016/j.jaad.2008.05.007
State	Published - Nov 2008

ASJC Scopus subject areas

Dermatology

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10.1016/j.jaad.2008.05.007

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title = "Acquired cutis laxa associated with heavy chain deposition disease",

abstract = "Acquired cutis laxa (generalized acquired elastolysis) is a condition of unknown etiology characterized by a degeneration of elastic fibers in the skin, resulting in laxity with reduced elastic recoil. We describe a patient with acquired cutis laxa associated with an underlying heavy chain deposition disease. Direct immunofluorescence testing of lesional skin demonstrated immunoglobulin G deposition on elastic fibers, suggesting that in some cases, cutis laxa may have an immune-mediated etiopathogenesis.",

author = "Harrington, {Cynthia R.} and Beswick, {Tracy C.} and Susa, {Joseph S.} and Pandya, {Amit G.}",

year = "2008",

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AU - Harrington, Cynthia R.

AU - Beswick, Tracy C.

AU - Susa, Joseph S.

AU - Pandya, Amit G.

PY - 2008/11

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N2 - Acquired cutis laxa (generalized acquired elastolysis) is a condition of unknown etiology characterized by a degeneration of elastic fibers in the skin, resulting in laxity with reduced elastic recoil. We describe a patient with acquired cutis laxa associated with an underlying heavy chain deposition disease. Direct immunofluorescence testing of lesional skin demonstrated immunoglobulin G deposition on elastic fibers, suggesting that in some cases, cutis laxa may have an immune-mediated etiopathogenesis.

AB - Acquired cutis laxa (generalized acquired elastolysis) is a condition of unknown etiology characterized by a degeneration of elastic fibers in the skin, resulting in laxity with reduced elastic recoil. We describe a patient with acquired cutis laxa associated with an underlying heavy chain deposition disease. Direct immunofluorescence testing of lesional skin demonstrated immunoglobulin G deposition on elastic fibers, suggesting that in some cases, cutis laxa may have an immune-mediated etiopathogenesis.

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IS - 5 SUPPL.

ER -

Acquired cutis laxa associated with heavy chain deposition disease

Abstract

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