Acrokeratosis Verruciformis (Hopf) and Darier's Disease: Genetic Evidence for a Unitary Origin

James H. Herndon, Jean D. Wilson

Research output: Contribution to journalArticle

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Twelve members of a single family were found to exhibit a disorder of keratinization. Seven of these persons had findings characteristic of Ackrokeratosis Verruciformis (Hopf), one member or possibly two had Darier's disease, and three of the family had minor disturbances of keratinization. It was proposed that these disorders represent variable manifestations of a single underlying genetic defect in keratin formation.

Original languageEnglish (US)
Pages (from-to)305-310
Number of pages6
JournalArchives of Dermatology
Issue number3
Publication statusPublished - 1966


ASJC Scopus subject areas

  • Dermatology

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