Acute tubulointerstitial nephritis

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Acute tubulointerstitial nephritis (ATIN) is a common disorder characterized by a spectrum of clinical manifestations ranging from asymptomatic urinary abnormalities to acute oliguric renal failure. Tubular dysfunction out of proportion to the degree of renal failure is an important clue to the diagnosis. This review describes its pathogenesis, pathophysiology, diagnosis, differential diagnosis and therapy, emphasizing the drug-induced form of ATIN.

Original languageEnglish (US)
Pages (from-to)392-410
Number of pages19
JournalAmerican Journal of the Medical Sciences
Volume299
Issue number6
StatePublished - 1990

Fingerprint

Acute Kidney Injury
Renal Insufficiency
Differential Diagnosis
Drug Therapy
Acute Tubulointerstitial Nephritis

Keywords

  • Acute renal failure
  • Drugs
  • Hyperkalemic hyperchloremic metabolic acidosis
  • Tubulointerstitial nephritis

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Acute tubulointerstitial nephritis. / Toto, R. D.

In: American Journal of the Medical Sciences, Vol. 299, No. 6, 1990, p. 392-410.

Research output: Contribution to journalArticle

@article{5ab8498670454ddca00e0ea6132b0e73,
title = "Acute tubulointerstitial nephritis",
abstract = "Acute tubulointerstitial nephritis (ATIN) is a common disorder characterized by a spectrum of clinical manifestations ranging from asymptomatic urinary abnormalities to acute oliguric renal failure. Tubular dysfunction out of proportion to the degree of renal failure is an important clue to the diagnosis. This review describes its pathogenesis, pathophysiology, diagnosis, differential diagnosis and therapy, emphasizing the drug-induced form of ATIN.",
keywords = "Acute renal failure, Drugs, Hyperkalemic hyperchloremic metabolic acidosis, Tubulointerstitial nephritis",
author = "Toto, {R. D.}",
year = "1990",
language = "English (US)",
volume = "299",
pages = "392--410",
journal = "The American journal of the medical sciences",
issn = "0002-9629",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

TY - JOUR

T1 - Acute tubulointerstitial nephritis

AU - Toto, R. D.

PY - 1990

Y1 - 1990

N2 - Acute tubulointerstitial nephritis (ATIN) is a common disorder characterized by a spectrum of clinical manifestations ranging from asymptomatic urinary abnormalities to acute oliguric renal failure. Tubular dysfunction out of proportion to the degree of renal failure is an important clue to the diagnosis. This review describes its pathogenesis, pathophysiology, diagnosis, differential diagnosis and therapy, emphasizing the drug-induced form of ATIN.

AB - Acute tubulointerstitial nephritis (ATIN) is a common disorder characterized by a spectrum of clinical manifestations ranging from asymptomatic urinary abnormalities to acute oliguric renal failure. Tubular dysfunction out of proportion to the degree of renal failure is an important clue to the diagnosis. This review describes its pathogenesis, pathophysiology, diagnosis, differential diagnosis and therapy, emphasizing the drug-induced form of ATIN.

KW - Acute renal failure

KW - Drugs

KW - Hyperkalemic hyperchloremic metabolic acidosis

KW - Tubulointerstitial nephritis

UR - http://www.scopus.com/inward/record.url?scp=0025299030&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0025299030&partnerID=8YFLogxK

M3 - Article

VL - 299

SP - 392

EP - 410

JO - The American journal of the medical sciences

JF - The American journal of the medical sciences

SN - 0002-9629

IS - 6

ER -