Age less than two years is not a risk factor for mortality after mitral valve replacement in children

Daniela Y. Rafii, Ryan R Davies, Sheila J. Carroll, Jan M. Quaegebeur, Jonathan M. Chen

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Abstract

Background Outcomes for mitral valve replacement (MVR) in the pediatric population are generally reported as poor, particularly in patients less than 2 years old. We compared long-term morbidity and mortality associated with MVR between patients less than 2 years old and patients 2 to 18 years old. Methods We evaluated pediatric patients undergoing MVR from March 1990 to November 2007 at our institution. Morbidity and mortality was compared between patients less than 2 years and patients 2 to 18 years old. Primary endpoints measured were postoperative survival, long-term survival, reoperation, cerebrovascular accident or transient ischemic attack, and significant bleeding events. Results Forty-five patients underwent 54 MVRs. Median age was 3.1 years; 18 patients were under 2 years. Median follow-up time was 5.4 years. There was no statistically significant difference between long-term or short-term survival between the two age groups, with 30-day survival of 89% (younger patients) versus 100% (older patients), and 10-year survival of 82% (younger patients) versus 85% (older patients). Freedom from reoperation for the younger age group was 40% at 10 years versus 96% for the older patients, p = 0.003. Conclusions In our population, there was no statistically significant difference in survival between patients less than 2 years and patients 2 to 18 years. In children undergoing MVR, age less than 2 years remains a risk factor for reoperation but not for mortality.

Original languageEnglish (US)
Pages (from-to)1228-1234
Number of pages7
JournalAnnals of Thoracic Surgery
Volume91
Issue number4
DOIs
StatePublished - Apr 1 2011

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Mitral Valve
Mortality
Survival
Reoperation
Age Groups
Pediatrics
Morbidity
Transient Ischemic Attack
Population
Stroke

ASJC Scopus subject areas

  • Surgery
  • Pulmonary and Respiratory Medicine
  • Cardiology and Cardiovascular Medicine

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Age less than two years is not a risk factor for mortality after mitral valve replacement in children. / Rafii, Daniela Y.; Davies, Ryan R; Carroll, Sheila J.; Quaegebeur, Jan M.; Chen, Jonathan M.

In: Annals of Thoracic Surgery, Vol. 91, No. 4, 01.04.2011, p. 1228-1234.

Research output: Contribution to journalArticle

Rafii, Daniela Y. ; Davies, Ryan R ; Carroll, Sheila J. ; Quaegebeur, Jan M. ; Chen, Jonathan M. / Age less than two years is not a risk factor for mortality after mitral valve replacement in children. In: Annals of Thoracic Surgery. 2011 ; Vol. 91, No. 4. pp. 1228-1234.
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