ALCHEMIST: Bringing genomic discovery and targeted therapies to early-stage lung cancer

D. E. Gerber, G. R. Oxnard, R. Govindan

Research output: Contribution to journalArticle

32 Scopus citations


The identification of druggable molecular alterations represents one of the greatest advances in cancer treatment. Such progress is particularly evident for lung cancer, which now has numerous molecularly defined subsets such as epidermal growth factor receptor (EGFR) mutations and anaplastic lymphoma kinase (ALK) rearrangements. However, understanding of the significance of these genomic alterations is largely limited to incurable, metastatic lung cancer. ALCHEMIST (Adjuvant Lung Cancer Enrichment Marker Identification and Sequencing Trial) is a National Cancer Institute-sponsored initiative to address these questions in earlier-stage disease.

Original languageEnglish (US)
Pages (from-to)447-450
Number of pages4
JournalClinical Pharmacology and Therapeutics
Issue number5
Publication statusPublished - May 1 2015


ASJC Scopus subject areas

  • Medicine(all)

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