An acute bout of whole body passive hyperthermia increases plasma leptin, but does not alter glucose or insulin responses in obese type 2 diabetics and healthy adults

Eric Rivas, Dan E. Newmire, Craig G. Crandall, Philip L. Hooper, Vic Ben-Ezra

Research output: Contribution to journalArticle

8 Scopus citations

Abstract

Acute and chronic hyperthermic treatments in diabetic animal models repeatedly improve insulin sensitivity and glycemic control. Therefore, the purpose of this study was to test the hypothesis that an acute 1 h bout of hyperthermic treatment improves glucose, insulin, and leptin responses to an oral glucose challenge (OGTT) in obese type 2 diabetics and healthy humans. Nine obese (45±7.1% fat mass) type 2 diabetics (T2DM: 50.1±12y, 7.5±1.8% HbA1c) absent of insulin therapy and nine similar aged (41.1±13.7y) healthy non-obese controls (HC: 33.4±7.8% fat mass, P

Original languageEnglish (US)
Pages (from-to)26-33
Number of pages8
JournalJournal of Thermal Biology
Volume59
DOIs
StatePublished - Jul 1 2016

Keywords

  • Diabetes
  • Glycemic control
  • Hyperthermia
  • Leptin
  • Obesity
  • Thermal stress

ASJC Scopus subject areas

  • Physiology
  • Developmental Biology
  • Biochemistry
  • Agricultural and Biological Sciences(all)

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