An experimental study on the noise correlation properties of CBCT projection data

Hua Zhang, Luo Ouyang, Jianhua Ma, Jing Huang, Wufan Chen, Jing Wang

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this study, we systematically investigated the noise correlation properties among detector bins of CBCT projection data by analyzing repeated projection measurements. The measurements were performed on a TrueBeam on-board CBCT imaging system with a 4030CB flat panel detector. An anthropomorphic male pelvis phantom was used to acquire 500 repeated projection data at six different dose levels from 0.1 mAs to 1.6 mAs per projection at three fixed angles. To minimize the influence of the lag effect, lag correction was performed on the consecutively acquired projection data. The noise correlation coefficient between detector bin pairs was calculated from the corrected projection data. The noise correlation among CBCT projection data was then incorporated into the covariance matrix of the penalized weighted least-squares (PWLS) criterion for noise reduction of low-dose CBCT. The analyses of the repeated measurements show that noise correlation coefficients are non-zero between the nearest neighboring bins of CBCT projection data. The average noise correlation coefficients for the first- and second- order neighbors are 0.20 and 0.06, respectively. The noise correlation coefficients are independent of the dose level. Reconstruction of the pelvis phantom shows that the PWLS criterion with consideration of noise correlation results in a lower noise level as compared to the PWLS criterion without considering the noise correlation at the matched resolution.

Original languageEnglish (US)
Title of host publicationMedical Imaging 2014
Subtitle of host publicationPhysics of Medical Imaging
PublisherSPIE
ISBN (Print)9780819498267
DOIs
StatePublished - Jan 1 2014
EventMedical Imaging 2014: Physics of Medical Imaging - San Diego, CA, United States
Duration: Feb 17 2014Feb 20 2014

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume9033
ISSN (Print)1605-7422

Other

OtherMedical Imaging 2014: Physics of Medical Imaging
CountryUnited States
CitySan Diego, CA
Period2/17/142/20/14

Keywords

  • PWLS
  • low-dose CBCT
  • noise correlation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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    Zhang, H., Ouyang, L., Ma, J., Huang, J., Chen, W., & Wang, J. (2014). An experimental study on the noise correlation properties of CBCT projection data. In Medical Imaging 2014: Physics of Medical Imaging [90332R] (Progress in Biomedical Optics and Imaging - Proceedings of SPIE; Vol. 9033). SPIE. https://doi.org/10.1117/12.2043151