An International Atherosclerosis Society Position Paper: Global recommendations for the management of dyslipidemia - Full report

Scott M Grundy, Hidenori Arai, Philip Barter, Thomas P. Bersot, D. John Betteridge, Rafael Carmena, Ada Cuevas, Michael H. Davidson, Jacques Genest, Y. Antero Kesäniemi, Shaukat Sadikot, Raul D. Santos, Andrey V. Susekov, Rody G. Sy, S. LaleTokgözoglu, Gerald F. Watts, Dong Zhao

Research output: Contribution to journalArticle

216 Scopus citations

Abstract

An international panel of the International Atherosclerosis Society has developed a new set of recommendations for the management of dyslipidemia. The panel identifies non - high-density lipoprotein cholesterol as the major atherogenic lipoprotein. Primary and secondary prevention are considered separately. Optimal levels for atherogenic lipoproteins are derived for the two forms of prevention. For primary prevention, the recommendations emphasize lifestyle therapies to reduce atherogenic lipoproteins; drug therapy is reserved for subjects at greater risk. Risk assessment is based on estimation of lifetime risk according to differences in baseline population risk in different nations or regions. Secondary prevention emphasizes use of cholesterol-lowering drugs to attain optimal levels of atherogenic lipoproteins.

Original languageEnglish (US)
Pages (from-to)29-60
Number of pages32
JournalJournal of Clinical Lipidology
Volume8
Issue number1
DOIs
StatePublished - Jan 2014

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Keywords

  • Cholesterol
  • Dyslipidemia
  • Lifestyle therapies
  • Lifetime risk
  • Metabolic syndrome
  • Statins

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism
  • Internal Medicine
  • Nutrition and Dietetics

Cite this

Grundy, S. M., Arai, H., Barter, P., Bersot, T. P., Betteridge, D. J., Carmena, R., Cuevas, A., Davidson, M. H., Genest, J., Kesäniemi, Y. A., Sadikot, S., Santos, R. D., Susekov, A. V., Sy, R. G., LaleTokgözoglu, S., Watts, G. F., & Zhao, D. (2014). An International Atherosclerosis Society Position Paper: Global recommendations for the management of dyslipidemia - Full report. Journal of Clinical Lipidology, 8(1), 29-60. https://doi.org/10.1016/j.jacl.2013.12.005