An investigation of simultaneous variations in cerebral blood flow velocity and arterial blood pressure during Sleep Apnea

Raichel Alex, Gauri Bhave, Mohammad A. Al-Abed, Aditya Bashaboyina, Swathi Iyer, Donald E. Watenpaugh, Rong Zhang, Khosrow Behbehani

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations

Abstract

Obstructive Sleep Apnea (OSA) is a major sleep disorder with a prevalence of about 15 % among US adult population and can lead to cardiovascular diseases and stroke. In this study, we have investigated the OSA-induced concurrent rise in cerebral blood flow velocity and blood pressure in 5 positively diagnosed sleep apnea subjects. The subject population had a mean AHI of 57.94±25.73 and BMI of 33.66±7.27 kg/m2. The results of this preliminary study yielded a relatively high correlation between rise in blood pressure and rise in cerebral blood flow velocity during apnea episodes (r=0.61±0.16) compared to normal breathing (r=0.28±0.26). These findings suggest that cerebral autoregulation may be less effective during apnea episodes.

Original languageEnglish (US)
Title of host publicationProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
Pages5634-5637
Number of pages4
DOIs
Publication statusPublished - 2012
Event34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012 - San Diego, CA, United States
Duration: Aug 28 2012Sep 1 2012

Other

Other34th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS 2012
CountryUnited States
CitySan Diego, CA
Period8/28/129/1/12

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ASJC Scopus subject areas

  • Computer Vision and Pattern Recognition
  • Signal Processing
  • Biomedical Engineering
  • Health Informatics

Cite this

Alex, R., Bhave, G., Al-Abed, M. A., Bashaboyina, A., Iyer, S., Watenpaugh, D. E., ... Behbehani, K. (2012). An investigation of simultaneous variations in cerebral blood flow velocity and arterial blood pressure during Sleep Apnea. In Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS (pp. 5634-5637). [6347272] https://doi.org/10.1109/EMBC.2012.6347272