Analysis of the sources of uncertainty for EDR2 film-based IMRT quality assurance

Chengyu Shi, Nikos Papanikolaou, Yulong Yan, Xuejun Weng, Hongyu Jiang

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

In our institution, patient-specific quality assurance (QA) for intensity-modulated radiation therapy (IMRT) is usually performed by measuring the dose to a point using an ion chamber and by measuring the dose to a plane using film. In order to perform absolute dose comparison measurements using film, an accurate calibration curve should be used. In this paper, we investigate the film response curve uncertainty factors, including film batch differences, film processor temperature effect, film digitization, and treatment unit. In addition, we reviewed 50 patient-specific IMRT QA procedures performed in our institution in order to quantify the sources of error in film-based dosimetry. Our study showed that the EDR2 film dosimetry can be done with less than 3% uncertainty. The EDR2 film response was not affected by the choice of treatment unit provided the nominal energy was the same. This investigation of the different sources of uncertainties in the film calibration procedure can provide a better understanding of the film-based dosimetry and can improve quality control for IMRT QA.

Original languageEnglish (US)
Pages (from-to)1-8
Number of pages8
JournalJournal of Applied Clinical Medical Physics
Volume7
Issue number2
StatePublished - Mar 2006

Fingerprint

Film Dosimetry
Radiotherapy
assurance
Quality assurance
Uncertainty
radiation therapy
Calibration
Dosimetry
Quality Control
Research Design
dosimeters
Ions
Temperature
Therapeutics
dosage
Ionization chambers
Analog to digital conversion
ionization chambers
curves
quality control

Keywords

  • Calibration curve
  • EDR2
  • Film dosimetry
  • IMRT
  • Uncertainty

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiation
  • Instrumentation

Cite this

Analysis of the sources of uncertainty for EDR2 film-based IMRT quality assurance. / Shi, Chengyu; Papanikolaou, Nikos; Yan, Yulong; Weng, Xuejun; Jiang, Hongyu.

In: Journal of Applied Clinical Medical Physics, Vol. 7, No. 2, 03.2006, p. 1-8.

Research output: Contribution to journalArticle

Shi, Chengyu ; Papanikolaou, Nikos ; Yan, Yulong ; Weng, Xuejun ; Jiang, Hongyu. / Analysis of the sources of uncertainty for EDR2 film-based IMRT quality assurance. In: Journal of Applied Clinical Medical Physics. 2006 ; Vol. 7, No. 2. pp. 1-8.
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