Aquaporin-4 neuromyelitis optica spectrum disorder in a 2-year-old girl: Diagnostic and treatment considerations

Tuba Rashid Khan, Cynthia Wang

Research output: Contribution to journalArticle

Abstract

We describe a case of an unusually early and severe manifestation of Aquaporin-4 (AQP-4) positive Neuromyelitis Optica Spectrum Disorder (NMOSD) in a two-year-old girl. We discuss learning points from her clinical presentation and highlight differences between pediatric and adult presentations of the disease. We argue that AQP-4 NMOSD should always be considered in the differential diagnosis for any child presenting with an acute neuroimmunological process given the morbidity associated with the condition and the importance of early diagnosis and treatment.

Original languageEnglish (US)
Article number102030
JournalMultiple Sclerosis and Related Disorders
Volume41
DOIs
StatePublished - Jun 2020

Keywords

  • Aquaporin-4
  • Autoimmune neurology
  • Neuroimmunology
  • Neuromyelitis optica

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

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