Arterial spin-labeling in routine clinical practice, part 3

Hyperperfusion patterns

A. R. Deibler, J. M. Pollock, R. A. Kraft, H. Tan, J. H. Burdette, Joseph A. Maldjian

Research output: Contribution to journalReview article

97 Citations (Scopus)

Abstract

Arterial spin-labeled (ASL) perfusion imaging can be implemented successfully into a routine clinical neuroimaging protocol and can accurately demonstrate alterations in brain perfusion. We have observed patterns of focal, regional, and global hyperperfusion in a wide variety of disease processes. The causes of hyperperfusion at clinical ASL have not been previously characterized. Focal lesions such as brain tumors and vascular malformations with increased perfusion can be well depicted by ASL. More global causes of hyperperfusion, including postanoxia vasodilation and hypercapnia, may go undetected on conventional MR images, whereas the regional hyperperfusion, which may occur in reversible encephalopathies and luxury perfusion, has been consistently illustrated on ASL cerebral blood flow maps at our institution.

Original languageEnglish (US)
Pages (from-to)1428-1435
Number of pages8
JournalAmerican Journal of Neuroradiology
Volume29
Issue number8
DOIs
StatePublished - Sep 1 2008

Fingerprint

Perfusion
Cerebrovascular Circulation
Central Nervous System Vascular Malformations
Perfusion Imaging
Hypercapnia
Brain Diseases
Clinical Protocols
Neuroimaging
Vasodilation
Brain Neoplasms
Brain

ASJC Scopus subject areas

  • Clinical Neurology
  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Arterial spin-labeling in routine clinical practice, part 3 : Hyperperfusion patterns. / Deibler, A. R.; Pollock, J. M.; Kraft, R. A.; Tan, H.; Burdette, J. H.; Maldjian, Joseph A.

In: American Journal of Neuroradiology, Vol. 29, No. 8, 01.09.2008, p. 1428-1435.

Research output: Contribution to journalReview article

Deibler, A. R. ; Pollock, J. M. ; Kraft, R. A. ; Tan, H. ; Burdette, J. H. ; Maldjian, Joseph A. / Arterial spin-labeling in routine clinical practice, part 3 : Hyperperfusion patterns. In: American Journal of Neuroradiology. 2008 ; Vol. 29, No. 8. pp. 1428-1435.
@article{d85997f43f0a405f8e10a231589831ca,
title = "Arterial spin-labeling in routine clinical practice, part 3: Hyperperfusion patterns",
abstract = "Arterial spin-labeled (ASL) perfusion imaging can be implemented successfully into a routine clinical neuroimaging protocol and can accurately demonstrate alterations in brain perfusion. We have observed patterns of focal, regional, and global hyperperfusion in a wide variety of disease processes. The causes of hyperperfusion at clinical ASL have not been previously characterized. Focal lesions such as brain tumors and vascular malformations with increased perfusion can be well depicted by ASL. More global causes of hyperperfusion, including postanoxia vasodilation and hypercapnia, may go undetected on conventional MR images, whereas the regional hyperperfusion, which may occur in reversible encephalopathies and luxury perfusion, has been consistently illustrated on ASL cerebral blood flow maps at our institution.",
author = "Deibler, {A. R.} and Pollock, {J. M.} and Kraft, {R. A.} and H. Tan and Burdette, {J. H.} and Maldjian, {Joseph A.}",
year = "2008",
month = "9",
day = "1",
doi = "10.3174/ajnr.A1034",
language = "English (US)",
volume = "29",
pages = "1428--1435",
journal = "American Journal of Neuroradiology",
issn = "0195-6108",
publisher = "American Society of Neuroradiology",
number = "8",

}

TY - JOUR

T1 - Arterial spin-labeling in routine clinical practice, part 3

T2 - Hyperperfusion patterns

AU - Deibler, A. R.

AU - Pollock, J. M.

AU - Kraft, R. A.

AU - Tan, H.

AU - Burdette, J. H.

AU - Maldjian, Joseph A.

PY - 2008/9/1

Y1 - 2008/9/1

N2 - Arterial spin-labeled (ASL) perfusion imaging can be implemented successfully into a routine clinical neuroimaging protocol and can accurately demonstrate alterations in brain perfusion. We have observed patterns of focal, regional, and global hyperperfusion in a wide variety of disease processes. The causes of hyperperfusion at clinical ASL have not been previously characterized. Focal lesions such as brain tumors and vascular malformations with increased perfusion can be well depicted by ASL. More global causes of hyperperfusion, including postanoxia vasodilation and hypercapnia, may go undetected on conventional MR images, whereas the regional hyperperfusion, which may occur in reversible encephalopathies and luxury perfusion, has been consistently illustrated on ASL cerebral blood flow maps at our institution.

AB - Arterial spin-labeled (ASL) perfusion imaging can be implemented successfully into a routine clinical neuroimaging protocol and can accurately demonstrate alterations in brain perfusion. We have observed patterns of focal, regional, and global hyperperfusion in a wide variety of disease processes. The causes of hyperperfusion at clinical ASL have not been previously characterized. Focal lesions such as brain tumors and vascular malformations with increased perfusion can be well depicted by ASL. More global causes of hyperperfusion, including postanoxia vasodilation and hypercapnia, may go undetected on conventional MR images, whereas the regional hyperperfusion, which may occur in reversible encephalopathies and luxury perfusion, has been consistently illustrated on ASL cerebral blood flow maps at our institution.

UR - http://www.scopus.com/inward/record.url?scp=51649119606&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=51649119606&partnerID=8YFLogxK

U2 - 10.3174/ajnr.A1034

DO - 10.3174/ajnr.A1034

M3 - Review article

VL - 29

SP - 1428

EP - 1435

JO - American Journal of Neuroradiology

JF - American Journal of Neuroradiology

SN - 0195-6108

IS - 8

ER -