Arteries engineered from vascular cells

L. E. Niklason, Jinming Gao, William Abbott, Karen Hirschi, Stuart Houser, Robert Marini, Robert Langer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. A `biomimetic' pulsatile perfusion system was developed which mimicked some of the physical forces experienced by native arteries in vivo. Tissue engineered arteries were also made from porcine vascular cells, and were implanted in miniature swine, with patency documented up to 24 days by digital angiography.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Place of PublicationPiscataway, NJ, United States
PublisherIEEE
Pages747
Number of pages1
Volume2
ISBN (Print)0780356756
StatePublished - 1999
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

Fingerprint

Tissue
Angiography
Biopsy
Endothelial cells
Biomimetics
Tissue engineering
Grafts
Muscle

ASJC Scopus subject areas

  • Bioengineering

Cite this

Niklason, L. E., Gao, J., Abbott, W., Hirschi, K., Houser, S., Marini, R., & Langer, R. (1999). Arteries engineered from vascular cells. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Vol. 2, pp. 747). Piscataway, NJ, United States: IEEE.

Arteries engineered from vascular cells. / Niklason, L. E.; Gao, Jinming; Abbott, William; Hirschi, Karen; Houser, Stuart; Marini, Robert; Langer, Robert.

Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 Piscataway, NJ, United States : IEEE, 1999. p. 747.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Niklason, LE, Gao, J, Abbott, W, Hirschi, K, Houser, S, Marini, R & Langer, R 1999, Arteries engineered from vascular cells. in Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. vol. 2, IEEE, Piscataway, NJ, United States, pp. 747, Proceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS), Atlanta, GA, USA, 10/13/99.
Niklason LE, Gao J, Abbott W, Hirschi K, Houser S, Marini R et al. Arteries engineered from vascular cells. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2. Piscataway, NJ, United States: IEEE. 1999. p. 747
Niklason, L. E. ; Gao, Jinming ; Abbott, William ; Hirschi, Karen ; Houser, Stuart ; Marini, Robert ; Langer, Robert. / Arteries engineered from vascular cells. Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings. Vol. 2 Piscataway, NJ, United States : IEEE, 1999. pp. 747
@inproceedings{6a4233301d00471ca3a38822c8627ddb,
title = "Arteries engineered from vascular cells",
abstract = "A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. A `biomimetic' pulsatile perfusion system was developed which mimicked some of the physical forces experienced by native arteries in vivo. Tissue engineered arteries were also made from porcine vascular cells, and were implanted in miniature swine, with patency documented up to 24 days by digital angiography.",
author = "Niklason, {L. E.} and Jinming Gao and William Abbott and Karen Hirschi and Stuart Houser and Robert Marini and Robert Langer",
year = "1999",
language = "English (US)",
isbn = "0780356756",
volume = "2",
pages = "747",
booktitle = "Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings",
publisher = "IEEE",

}

TY - GEN

T1 - Arteries engineered from vascular cells

AU - Niklason, L. E.

AU - Gao, Jinming

AU - Abbott, William

AU - Hirschi, Karen

AU - Houser, Stuart

AU - Marini, Robert

AU - Langer, Robert

PY - 1999

Y1 - 1999

N2 - A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. A `biomimetic' pulsatile perfusion system was developed which mimicked some of the physical forces experienced by native arteries in vivo. Tissue engineered arteries were also made from porcine vascular cells, and were implanted in miniature swine, with patency documented up to 24 days by digital angiography.

AB - A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. A `biomimetic' pulsatile perfusion system was developed which mimicked some of the physical forces experienced by native arteries in vivo. Tissue engineered arteries were also made from porcine vascular cells, and were implanted in miniature swine, with patency documented up to 24 days by digital angiography.

UR - http://www.scopus.com/inward/record.url?scp=0033353988&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0033353988&partnerID=8YFLogxK

M3 - Conference contribution

SN - 0780356756

VL - 2

SP - 747

BT - Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings

PB - IEEE

CY - Piscataway, NJ, United States

ER -