Arteries engineered from vascular cells

L. E. Niklason, Jinming Gao, William Abbott, Karen Hirschi, Stuart Houser, Robert Marini, Robert Langer

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

A tissue engineering approach was developed to produce arbitrary lengths of vascular graft material from smooth muscle and endothelial cells that were derived from a biopsy of vascular tissue. A `biomimetic' pulsatile perfusion system was developed which mimicked some of the physical forces experienced by native arteries in vivo. Tissue engineered arteries were also made from porcine vascular cells, and were implanted in miniature swine, with patency documented up to 24 days by digital angiography.

Original languageEnglish (US)
Title of host publicationAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
PublisherIEEE
Number of pages1
ISBN (Print)0780356756
StatePublished - Dec 1 1999
EventProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS) - Atlanta, GA, USA
Duration: Oct 13 1999Oct 16 1999

Publication series

NameAnnual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings
Volume2
ISSN (Print)0589-1019

Other

OtherProceedings of the 1999 IEEE Engineering in Medicine and Biology 21st Annual Conference and the 1999 Fall Meeting of the Biomedical Engineering Society (1st Joint BMES / EMBS)
CityAtlanta, GA, USA
Period10/13/9910/16/99

ASJC Scopus subject areas

  • Signal Processing
  • Biomedical Engineering
  • Computer Vision and Pattern Recognition
  • Health Informatics

Fingerprint Dive into the research topics of 'Arteries engineered from vascular cells'. Together they form a unique fingerprint.

  • Cite this

    Niklason, L. E., Gao, J., Abbott, W., Hirschi, K., Houser, S., Marini, R., & Langer, R. (1999). Arteries engineered from vascular cells. In Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings (Annual International Conference of the IEEE Engineering in Medicine and Biology - Proceedings; Vol. 2). IEEE.