Assessing the current role of platelet function testing

Eugene Braunwald; Dominick Angiolillo; Eric Bates; Peter B. Berger; Deepak Bhatt; Christopher P. Cannon; Mark I. Furman; Paul Gurbel; Alan D. Michelson; Eric Peterson; Stephen Wiviott

doi:10.1002/clc.20361

Assessing the current role of platelet function testing

Eugene Braunwald, Dominick Angiolillo, Eric Bates, Peter B. Berger, Deepak Bhatt, Christopher P. Cannon, Mark I. Furman, Paul Gurbel, Alan D. Michelson, Eric Peterson, Stephen Wiviott

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

In vitro platelet function tests are commonly applied in research and offer justification for using antiplatelet therapy. However, studies assessing the ability of standardized platelet function tests to predict patients' clinical response to aspirin or clopidogrel have generated contradictory results. At this time, there is no standardized definition for resistance to antiplatelet therapy, and the appropriate treatment of patients who are hyporesponsive to these agents is not known. Although such tests have a role in research, their place in guiding therapy remains to be established, and prospective trials are urgently needed. The ideal platelet function test for clinical practice would be rapid, easy-to-use, inexpensive, and reliable.

Original language	English (US)
Pages (from-to)	I10-I16
Journal	Clinical Cardiology
Volume	31
Issue number	3 SUUPL. 1
DOIs	https://doi.org/10.1002/clc.20361
State	Published - Mar 2008
Externally published	Yes

Keywords

Acute coronary syndromes <ischemic heart disease
Catheterization/diagnostic interventional <cardiac
Platelets
Thrombosis/hypercoagulable states

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine

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10.1002/clc.20361

Cite this

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AU - Angiolillo, Dominick

AU - Bates, Eric

AU - Berger, Peter B.

AU - Bhatt, Deepak

AU - Cannon, Christopher P.

AU - Furman, Mark I.

AU - Gurbel, Paul

AU - Michelson, Alan D.

AU - Peterson, Eric

AU - Wiviott, Stephen

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Assessing the current role of platelet function testing

Abstract

Keywords

ASJC Scopus subject areas

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