Association between low ankle-brachial index and accelerometer-derived sedentary and exercise time in the asymptomatic general population

Research output: Contribution to journalArticle

9 Scopus citations

Abstract

Sedentary behavior is an adverse health risk factor that is independent of physical activity. The relationship between sedentary behavior, exercise activity and the ankle-brachial index (ABI) is not well understood. We analyzed data from the National Health and Nutrition Examination Survey (NHANES) 2003-2004. Accelerometer data were used to quantify exercise and sedentary time for each participant. A low ABI was defined as a value <1.0 (including borderline values). Multi-variable adjusted logistic regression analyses were performed with sedentary and exercise times as independent variables, adjusting for important confounders. There were 1443 asymptomatic participants (mean age 61 years, 49% female, 55% current/prior smokers) with mean daily sedentary and exercise times of 454±144 and 18±20 minutes, respectively. Of the participants, 23% had an ABI <1.0 (8.7% with ABI <0.9). Sedentary time was positively associated with a low ABI (odds ratio [OR] 1.22 per 1 standard deviation [SD], [95% confidence interval (CI), 1.03-1.43]; p=0.02) while exercise time was inversely associated with a low ABI (OR 0.71 per 1 SD, [95% CI, 0.57-0.89]; p=0.003). Sedentary time is associated with low ABI values in the asymptomatic population. This association appears to be independent of exercise time and warrants further investigation.

Original languageEnglish (US)
Pages (from-to)332-338
Number of pages7
JournalVascular Medicine (United Kingdom)
Volume20
Issue number4
DOIs
StatePublished - Aug 10 2015

Keywords

  • accelerometer
  • ankle-brachial index
  • National Health and Nutrition Examination Survey (NHANES)
  • peripheral arterial disease
  • physical activity
  • sedentary

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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