TY - JOUR
T1 - Association of non-high-density lipoprotein cholesterol with psychosocial dysfunction in children and adolescents with obesity
AU - Serrano-Gonzalez, Monica
AU - McConnel, Charles
AU - Bokhary, Mahmoud
AU - Oden, Jon
AU - Lopez, Ximena
N1 - Publisher Copyright:
© Mary Ann Liebert, Inc.
PY - 2015/10/1
Y1 - 2015/10/1
N2 - Background: Children with obesity have worse psychosocial functioning compared to their nonoverweight peers. Adult studies suggest that several metabolic factors may participate in the etiology of depression in obesity. Methods: We evaluated the association of several metabolic parameters with psychosocial dysfunction in children with obesity, through a retrospective review of electronic medical records in patients ages 6-17. All parents were asked to complete the Pediatric Symptom Checklist (PSC) questionnaire, a validated measurement of psychosocial dysfunction in children. Results: PSC scores were available in 618 patients. Overall, 11.2% of patients had a PSC score ≥28, suggestive of psychosocial dysfunction. Non-high-density lipoprotein (HDL) cholesterol was associated with a higher PSC score (p=0.02), after adjusting for age, sex, race, socioeconomic status, and BMI z-score. Conclusions: Consistent with adult studies, in children and adolescents with obesity, non-HDL cholesterol may play a role in the etiology of psychosocial dysfunction. Further studies are warranted.
AB - Background: Children with obesity have worse psychosocial functioning compared to their nonoverweight peers. Adult studies suggest that several metabolic factors may participate in the etiology of depression in obesity. Methods: We evaluated the association of several metabolic parameters with psychosocial dysfunction in children with obesity, through a retrospective review of electronic medical records in patients ages 6-17. All parents were asked to complete the Pediatric Symptom Checklist (PSC) questionnaire, a validated measurement of psychosocial dysfunction in children. Results: PSC scores were available in 618 patients. Overall, 11.2% of patients had a PSC score ≥28, suggestive of psychosocial dysfunction. Non-high-density lipoprotein (HDL) cholesterol was associated with a higher PSC score (p=0.02), after adjusting for age, sex, race, socioeconomic status, and BMI z-score. Conclusions: Consistent with adult studies, in children and adolescents with obesity, non-HDL cholesterol may play a role in the etiology of psychosocial dysfunction. Further studies are warranted.
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U2 - 10.1089/chi.2015.0043
DO - 10.1089/chi.2015.0043
M3 - Article
C2 - 26382177
AN - SCOPUS:84943401411
SN - 2153-2168
VL - 11
SP - 647
EP - 649
JO - Childhood Obesity
JF - Childhood Obesity
IS - 5
ER -