Association of non-high-density lipoprotein cholesterol with psychosocial dysfunction in children and adolescents with obesity

Monica Serrano-Gonzalez, Charles McConnel, Mahmoud Bokhary, Jon Oden, Ximena Lopez

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Background: Children with obesity have worse psychosocial functioning compared to their nonoverweight peers. Adult studies suggest that several metabolic factors may participate in the etiology of depression in obesity. Methods: We evaluated the association of several metabolic parameters with psychosocial dysfunction in children with obesity, through a retrospective review of electronic medical records in patients ages 6-17. All parents were asked to complete the Pediatric Symptom Checklist (PSC) questionnaire, a validated measurement of psychosocial dysfunction in children. Results: PSC scores were available in 618 patients. Overall, 11.2% of patients had a PSC score ≥28, suggestive of psychosocial dysfunction. Non-high-density lipoprotein (HDL) cholesterol was associated with a higher PSC score (p=0.02), after adjusting for age, sex, race, socioeconomic status, and BMI z-score. Conclusions: Consistent with adult studies, in children and adolescents with obesity, non-HDL cholesterol may play a role in the etiology of psychosocial dysfunction. Further studies are warranted.

Original languageEnglish (US)
Pages (from-to)647-649
Number of pages3
JournalChildhood Obesity
Volume11
Issue number5
DOIs
StatePublished - Oct 1 2015

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Endocrinology, Diabetes and Metabolism
  • Nutrition and Dietetics

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