Bath salt intoxication causing acute kidney injury requiring hemodialysis

Hariharan Regunath, Venkatesh Kumar Ariyamuthu, Pranavkumar Dalal, Madhukar Misra

Research output: Contribution to journalArticle

24 Citations (Scopus)

Abstract

Traditional bath salts contain a combination of inorganic salts like Epsom salts, table salt, baking soda, sodium metaphosphate, and borax that have cleansing properties. Since 2010, there have been rising concerns about a new type of substance abuse in the name of "bath salts." They are beta-ketone amphetamine analogs and are derivates of cathinone, a naturally occurring amphetamine analog found in the "khat" plant (Catha edulis). Effects reported with intake included increased energy, empathy, openness, and increased libido. Serious adverse effects reported with intoxication included cardiac, psychiatric, and neurological signs and symptoms. Not much is known about the toxicology and metabolism of these compounds. They inhibit monoamine reuptake (dopamine, nor epinephrine, etc.) and act as central nervous system stimulants with high additive and abuse potential because of their clinical and biochemical similarities to effects from use of cocaine, amphetamine, and 3,4-methylenedioxy-N-methylamphetamine. Deaths associated with use of these compounds have also been reported. We report a case of acute kidney injury associated with the use of "bath salt" pills that improved with hemodialysis.

Original languageEnglish (US)
JournalHemodialysis International
Volume16
Issue numberSUPPL. 1
DOIs
StatePublished - Oct 1 2012

Fingerprint

Baths
Acute Kidney Injury
Renal Dialysis
Salts
Amphetamine
Catha
Dietary Sodium Chloride
Central Nervous System Stimulants
Libido
Sodium Bicarbonate
Methamphetamine
Ketones
Cocaine
Toxicology
Epinephrine
Signs and Symptoms
Substance-Related Disorders
Psychiatry
Dopamine
Sodium

Keywords

  • Bath salts
  • Hemodialysis
  • Recreational drugs
  • Renal failure

ASJC Scopus subject areas

  • Hematology
  • Nephrology

Cite this

Bath salt intoxication causing acute kidney injury requiring hemodialysis. / Regunath, Hariharan; Ariyamuthu, Venkatesh Kumar; Dalal, Pranavkumar; Misra, Madhukar.

In: Hemodialysis International, Vol. 16, No. SUPPL. 1, 01.10.2012.

Research output: Contribution to journalArticle

Regunath, Hariharan ; Ariyamuthu, Venkatesh Kumar ; Dalal, Pranavkumar ; Misra, Madhukar. / Bath salt intoxication causing acute kidney injury requiring hemodialysis. In: Hemodialysis International. 2012 ; Vol. 16, No. SUPPL. 1.
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