Bilateral tubulocystic renal cell carcinomas in diabetic end-stage renal disease: First case report with cytogenetic and ultrastructural studies

Max Xiangtian Kong, Christopher Hale, Antonio Subietas-Mayol, Peng Lee, Nicholas D. Cassai, Gerald McRae, David S. Goldfarb, Ming Zhou, Rosemary Wieczorek

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

Tubulocystic renal cell carcinoma (TC-RCC) is a rare renal tumor composed of well-differentiated tubules and cysts lined by neoplastic cells with eosinophilic cytoplasm and prominent nucleoli. The origin of the tumor cells is still controversial. TC-RCC typically arises unilaterally. Involvement of both kidneys by multifocal TC-RCC has not been reported. In this study we report the first case of bilateral and multifocal TC-RCC. Immunohistochemical, cytogenetic and ultrastructural studies suggest TC-RCC is closely related to papillary RCC.

Original languageEnglish (US)
Article numbere57
Pages (from-to)185-188
Number of pages4
JournalRare Tumors
Volume5
Issue number4
DOIs
StatePublished - Nov 7 2013

Keywords

  • Cytogenetics
  • Immunohistochemistry
  • Renal cell carcinoma
  • Tubulocystic car-cinoma

ASJC Scopus subject areas

  • Histology
  • Oncology

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