Bilateral tubulocystic renal cell carcinomas in diabetic end-stage renal disease: First case report with cytogenetic and ultrastructural studies

Max Xiangtian Kong; Christopher Hale; Antonio Subietas-Mayol; Peng Lee; Nicholas D. Cassai; Gerald McRae; David S. Goldfarb; Ming Zhou; Rosemary Wieczorek

doi:10.4081/rt.2013.e57

Bilateral tubulocystic renal cell carcinomas in diabetic end-stage renal disease: First case report with cytogenetic and ultrastructural studies

Max Xiangtian Kong, Christopher Hale, Antonio Subietas-Mayol, Peng Lee, Nicholas D. Cassai, Gerald McRae, David S. Goldfarb, Ming Zhou, Rosemary Wieczorek

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Tubulocystic renal cell carcinoma (TC-RCC) is a rare renal tumor composed of well-differentiated tubules and cysts lined by neoplastic cells with eosinophilic cytoplasm and prominent nucleoli. The origin of the tumor cells is still controversial. TC-RCC typically arises unilaterally. Involvement of both kidneys by multifocal TC-RCC has not been reported. In this study we report the first case of bilateral and multifocal TC-RCC. Immunohistochemical, cytogenetic and ultrastructural studies suggest TC-RCC is closely related to papillary RCC.

Original language	English (US)
Article number	e57
Pages (from-to)	185-188
Number of pages	4
Journal	Rare Tumors
Volume	5
Issue number	4
DOIs	https://doi.org/10.4081/rt.2013.e57
State	Published - Nov 7 2013

Keywords

Cytogenetics
Immunohistochemistry
Renal cell carcinoma
Tubulocystic car-cinoma

ASJC Scopus subject areas

Histology
Oncology

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10.4081/rt.2013.e57

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title = "Bilateral tubulocystic renal cell carcinomas in diabetic end-stage renal disease: First case report with cytogenetic and ultrastructural studies",

abstract = "Tubulocystic renal cell carcinoma (TC-RCC) is a rare renal tumor composed of well-differentiated tubules and cysts lined by neoplastic cells with eosinophilic cytoplasm and prominent nucleoli. The origin of the tumor cells is still controversial. TC-RCC typically arises unilaterally. Involvement of both kidneys by multifocal TC-RCC has not been reported. In this study we report the first case of bilateral and multifocal TC-RCC. Immunohistochemical, cytogenetic and ultrastructural studies suggest TC-RCC is closely related to papillary RCC.",

keywords = "Cytogenetics, Immunohistochemistry, Renal cell carcinoma, Tubulocystic car-cinoma",

author = "Kong, {Max Xiangtian} and Christopher Hale and Antonio Subietas-Mayol and Peng Lee and Cassai, {Nicholas D.} and Gerald McRae and Goldfarb, {David S.} and Ming Zhou and Rosemary Wieczorek",

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T1 - Bilateral tubulocystic renal cell carcinomas in diabetic end-stage renal disease

T2 - First case report with cytogenetic and ultrastructural studies

AU - Kong, Max Xiangtian

AU - Hale, Christopher

AU - Subietas-Mayol, Antonio

AU - Lee, Peng

AU - Cassai, Nicholas D.

AU - McRae, Gerald

AU - Goldfarb, David S.

AU - Zhou, Ming

AU - Wieczorek, Rosemary

PY - 2013/11/7

Y1 - 2013/11/7

N2 - Tubulocystic renal cell carcinoma (TC-RCC) is a rare renal tumor composed of well-differentiated tubules and cysts lined by neoplastic cells with eosinophilic cytoplasm and prominent nucleoli. The origin of the tumor cells is still controversial. TC-RCC typically arises unilaterally. Involvement of both kidneys by multifocal TC-RCC has not been reported. In this study we report the first case of bilateral and multifocal TC-RCC. Immunohistochemical, cytogenetic and ultrastructural studies suggest TC-RCC is closely related to papillary RCC.

AB - Tubulocystic renal cell carcinoma (TC-RCC) is a rare renal tumor composed of well-differentiated tubules and cysts lined by neoplastic cells with eosinophilic cytoplasm and prominent nucleoli. The origin of the tumor cells is still controversial. TC-RCC typically arises unilaterally. Involvement of both kidneys by multifocal TC-RCC has not been reported. In this study we report the first case of bilateral and multifocal TC-RCC. Immunohistochemical, cytogenetic and ultrastructural studies suggest TC-RCC is closely related to papillary RCC.

KW - Cytogenetics

KW - Immunohistochemistry

KW - Renal cell carcinoma

KW - Tubulocystic car-cinoma

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Bilateral tubulocystic renal cell carcinomas in diabetic end-stage renal disease: First case report with cytogenetic and ultrastructural studies

Abstract

Keywords

ASJC Scopus subject areas

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