Biochemistry of Development: Striated Muscle

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Striated muscles are the cardiac and skeletal muscles that have distinct bands when viewed by a microscope. Although cardiac and skeletal muscles appear similar, they originate from different progenitor cells and use different evolutionarily conserved networks of transcription factors and microRNAs to regulate the programs controlling cell differentiation and morphogenesis during development. Elucidating the genetic networks that govern striated muscle development not only yields insights into general principles of organogenesis, but also facilitates therapies for cardiac and skeletal muscle diseases.

Original languageEnglish (US)
Title of host publicationEncyclopedia of Biological Chemistry
Subtitle of host publicationSecond Edition
PublisherElsevier Inc.
Pages179-186
Number of pages8
ISBN (Electronic)9780123786319
ISBN (Print)9780123786302
DOIs
StatePublished - Feb 15 2013

Keywords

  • Cardiac muscle
  • Cardiogenesis
  • Heart field
  • MicroRNA
  • Myogenesis
  • Sarcomere
  • Skeletal muscle
  • Somite
  • Transcription factor

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Biochemistry of Development: Striated Muscle'. Together they form a unique fingerprint.

  • Cite this

    Bassel-Duby, R., & Olson, E. N. (2013). Biochemistry of Development: Striated Muscle. In Encyclopedia of Biological Chemistry: Second Edition (pp. 179-186). Elsevier Inc.. https://doi.org/10.1016/B978-0-12-378630-2.00091-8