Bioresorbable polymeric stents: Current status and future promise

Robert C. Eberhart, Shih Horng Su, Kytai Truong Nguyen, Meital Zilberman, Liping Tang, Kevin D. Nelson, Peter Frenkel

Research output: Contribution to journalReview article

64 Scopus citations

Abstract

Metal stents and, more recently, polymer-coated metal stents are used to stabilize dissections, eliminate vessel recoil, and guide remodeling after balloon angioplasty and other treatments for arterial disease. Bioresorbable polymeric stents are being developed to improve the biocompatibility and the drug reservoir capacity of metal stents, and to offer a transient alternative to the permanent metallic stent implant. Following a brief review of metal stent technology, the emerging class of expandable, bioresorbable polymeric stents is described, with emphasis on developments in the authors' laboratory.

Original languageEnglish (US)
Pages (from-to)299-312
Number of pages14
JournalJournal of Biomaterials Science, Polymer Edition
Volume14
Issue number4
DOIs
StatePublished - May 19 2003

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Keywords

  • Bioresorbable polymeric
  • Drug delivery
  • Gene therapy
  • In-stent restenosis
  • Stent

ASJC Scopus subject areas

  • Biophysics
  • Bioengineering
  • Biomaterials
  • Biomedical Engineering

Cite this

Eberhart, R. C., Su, S. H., Nguyen, K. T., Zilberman, M., Tang, L., Nelson, K. D., & Frenkel, P. (2003). Bioresorbable polymeric stents: Current status and future promise. Journal of Biomaterials Science, Polymer Edition, 14(4), 299-312. https://doi.org/10.1163/156856203321478838