Bone Mineral Density Is Negatively Associated With Arterial Stiffness in Men With Hypertension

Xue Song Li, Hui He, Yi Lin Zhao, Ying Li, Zhi Ping Liu, Tiemin Liu, Yong Zhang, Kai Jiang Yu, Rui Tao Wang

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Hypertension (HTN) and osteoporosis are associated with the development and progress of atherosclerosis. However, little research has been conducted to examine the relationship between arterial stiffness and bone mineral density (BMD) in men with HTN. This cross-sectional study recruited 355 men with HTN and 353 control patients without HTN. Brachial-ankle pulse wave velocity (baPWV) and BMD measurements were performed. BMD was decreased and baPWV was elevated in patients with HTN compared with control patients (femoral neck [FN] BMD in the HTN and control groups were 0.662±0.195 g/cm2 and 0.713±0.204 g/cm2, respectively [P=.001], and baPWV in the HTN and control groups were 1403.3±156.8 cm/s and 1354.8±136.0 cm/s, respectively [P<.001]). Multiple linear regression analysis demonstrated that FN BMD was negatively associated with increased baPWV in HTN. Reduced FN BMD may be an independent factor for baPWV in patients with HTN.

Original languageEnglish (US)
Pages (from-to)1106-1111
Number of pages6
JournalJournal of Clinical Hypertension
Volume18
Issue number11
DOIs
StatePublished - Nov 1 2016

ASJC Scopus subject areas

  • Internal Medicine
  • Endocrinology, Diabetes and Metabolism
  • Cardiology and Cardiovascular Medicine

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    Li, X. S., He, H., Zhao, Y. L., Li, Y., Liu, Z. P., Liu, T., Zhang, Y., Yu, K. J., & Wang, R. T. (2016). Bone Mineral Density Is Negatively Associated With Arterial Stiffness in Men With Hypertension. Journal of Clinical Hypertension, 18(11), 1106-1111. https://doi.org/10.1111/jch.12848