Brain elasticity changes with ventriculomegaly

F. H. Sklar, J. T. Diehl, C. W. Beyer, W. Kemp Clark

Research output: Contribution to journalArticle

42 Citations (Scopus)

Abstract

The pressure-volume relationship of brain elasticity was determined in 32 patients during servo-controlled variable-rate lumbar infusions to measure net cerebrospinal fluid (CSF) absorptive capacity. Several indices were used to estimate ventricular size from computerized tomography scans. The results show a linear relationship between ventricular size and the elasticity slope which relates the natural logarithm of pressure to volume. It follows that a hydrocephalic patient should show a greater intracranial pulse amplitude at a given pressure than does a patient with normal-sized ventricles. Although these elasticity changes may simply be the result of the ventriculomegaly, it seems possible that the pressure-volume elasticity relationship may be of etiological importance in disorders of the CSF system.

Original languageEnglish (US)
Pages (from-to)173-179
Number of pages7
JournalJournal of Neurosurgery
Volume53
Issue number2
StatePublished - 1980

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Elasticity
Pressure
Brain
Cerebrospinal Fluid
Tomography

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Sklar, F. H., Diehl, J. T., Beyer, C. W., & Kemp Clark, W. (1980). Brain elasticity changes with ventriculomegaly. Journal of Neurosurgery, 53(2), 173-179.

Brain elasticity changes with ventriculomegaly. / Sklar, F. H.; Diehl, J. T.; Beyer, C. W.; Kemp Clark, W.

In: Journal of Neurosurgery, Vol. 53, No. 2, 1980, p. 173-179.

Research output: Contribution to journalArticle

Sklar, FH, Diehl, JT, Beyer, CW & Kemp Clark, W 1980, 'Brain elasticity changes with ventriculomegaly', Journal of Neurosurgery, vol. 53, no. 2, pp. 173-179.
Sklar FH, Diehl JT, Beyer CW, Kemp Clark W. Brain elasticity changes with ventriculomegaly. Journal of Neurosurgery. 1980;53(2):173-179.
Sklar, F. H. ; Diehl, J. T. ; Beyer, C. W. ; Kemp Clark, W. / Brain elasticity changes with ventriculomegaly. In: Journal of Neurosurgery. 1980 ; Vol. 53, No. 2. pp. 173-179.
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