TY - JOUR
T1 - Brain lesions in patients with multiple sclerosis
T2 - Detection with echo-planar imaging
AU - Siewert, Bettina
AU - Patel, Mahesh R.
AU - Mueller, Markus F.
AU - Gaa, Jochen
AU - Darby, David G.
AU - Poser, Charles M.
AU - Wielopolski, Piotr A.
AU - Edelman, Robert R.
AU - Warach, Steven
N1 - Copyright:
Copyright 2017 Elsevier B.V., All rights reserved.
PY - 1995/9
Y1 - 1995/9
N2 - PURPOSE: To evaluate the detection of brain lesions with echo-planar imaging relative to conventional spinecho (SE) imaging. MATERIALS AND METHODS: In 17 patients (three men, 14 women; mean age, 31 years) with multiple sclerosis, the following were compared: single-shot proton-density- and T2-weighted and thin-section T2-weighted echo-planar, proton-density- and T2-weighted multishot echo-planar, and conventional SE sequences. Quantitative and qualitative criteria as well as lesion detectability were evaluated. The proton-density-weighted SE sequence was used as the standard of reference. RESULTS: Multishot sequences were superior to single-shot sequences in image quality and lesion detectability. With the multishot proton-density-weighted sequence, 53 of 54 large lesions and 23 of 30 small lesions were detected; with the single-shot proton-density-weighted sequence, 38 of 54 large lesions and five of 30 small lesions were detected. CONCLUSION: With multishot echoplanar sequences, detectability of large lesions is similar to that with conventional SE imaging. Susceptibility artifact is diminished in comparison to single-shot echo-planar sequences.
AB - PURPOSE: To evaluate the detection of brain lesions with echo-planar imaging relative to conventional spinecho (SE) imaging. MATERIALS AND METHODS: In 17 patients (three men, 14 women; mean age, 31 years) with multiple sclerosis, the following were compared: single-shot proton-density- and T2-weighted and thin-section T2-weighted echo-planar, proton-density- and T2-weighted multishot echo-planar, and conventional SE sequences. Quantitative and qualitative criteria as well as lesion detectability were evaluated. The proton-density-weighted SE sequence was used as the standard of reference. RESULTS: Multishot sequences were superior to single-shot sequences in image quality and lesion detectability. With the multishot proton-density-weighted sequence, 53 of 54 large lesions and 23 of 30 small lesions were detected; with the single-shot proton-density-weighted sequence, 38 of 54 large lesions and five of 30 small lesions were detected. CONCLUSION: With multishot echoplanar sequences, detectability of large lesions is similar to that with conventional SE imaging. Susceptibility artifact is diminished in comparison to single-shot echo-planar sequences.
KW - Brain neoplasms, MR, 10.121411, 10.121416
KW - Magnetic resonance (MR), comparative studies, 10.121411, 10.121416
KW - Magnetic resonance (MR), echo planar, 10.121416
KW - Sclerosis, multiple, 10.871
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M3 - Article
C2 - 7644641
AN - SCOPUS:0029125911
SN - 0033-8419
VL - 196
SP - 765
EP - 771
JO - RADIOLOGY
JF - RADIOLOGY
IS - 3
ER -