Caenorhabditis elegans as an emerging model for virus-host interactions

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Since 1999, Caenorhabditis elegans has been extensively used to study microbe-host interactions due to its simple culture, genetic tractability, and susceptibility to numerous bacterial and fungal pathogens. In contrast, virus studies have been hampered by a lack of convenient virus infection models in nematodes. The recent discovery of a natural viral pathogen of C. elegans and development of diverse artificial infection models are providing new opportunities to explore virushost interplay in this powerful model organism.

Original languageEnglish (US)
Article numbere00509-17
JournalJournal of Virology
Volume91
Issue number23
DOIs
StatePublished - Dec 1 2017

Fingerprint

Caenorhabditis elegans
Viruses
viruses
Virus Diseases
Genetic Predisposition to Disease
pathogens
infection
Infection
Nematoda
microorganisms
organisms

Keywords

  • Caenorhabditis elegans
  • Flock House virus
  • Innate immunity
  • Orsay virus
  • RNA interference
  • Vesicular stomatitis virus
  • Virus-host interactions

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

Cite this

Caenorhabditis elegans as an emerging model for virus-host interactions. / Gammon, Don B.

In: Journal of Virology, Vol. 91, No. 23, e00509-17, 01.12.2017.

Research output: Contribution to journalArticle

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